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3. Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry. Durbin AD; Zimmerman MW; Dharia NV; Abraham BJ; Iniguez AB; Weichert-Leahey N; He S; Krill-Burger JM; Root DE; Vazquez F; Tsherniak A; Hahn WC; Golub TR; Young RA; Look AT; Stegmaier K Nat Genet; 2018 Sep; 50(9):1240-1246. PubMed ID: 30127528 [TBL] [Abstract][Full Text] [Related]
4. KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma. D'Oto A; Fang J; Jin H; Xu B; Singh S; Mullasseril A; Jones V; Abu-Zaid A; von Buttlar X; Cooke B; Hu D; Shohet J; Murphy AJ; Davidoff AM; Yang J Nat Commun; 2021 Dec; 12(1):7204. PubMed ID: 34893606 [TBL] [Abstract][Full Text] [Related]
5. A Novel MYCN-Specific Antigene Oligonucleotide Deregulates Mitochondria and Inhibits Tumor Growth in MYCN-Amplified Neuroblastoma. Montemurro L; Raieli S; Angelucci S; Bartolucci D; Amadesi C; Lampis S; Scardovi AL; Venturelli L; Nieddu G; Cerisoli L; Fischer M; Teti G; Falconi M; Pession A; Hrelia P; Tonelli R Cancer Res; 2019 Dec; 79(24):6166-6177. PubMed ID: 31615807 [TBL] [Abstract][Full Text] [Related]
6. Druggable epigenetic suppression of interferon-induced chemokine expression linked to Seier JA; Reinhardt J; Saraf K; Ng SS; Layer JP; Corvino D; Althoff K; Giordano FA; Schramm A; Fischer M; Hölzel M J Immunother Cancer; 2021 May; 9(5):. PubMed ID: 34016720 [TBL] [Abstract][Full Text] [Related]
7. Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas. Westermann F; Muth D; Benner A; Bauer T; Henrich KO; Oberthuer A; Brors B; Beissbarth T; Vandesompele J; Pattyn F; Hero B; König R; Fischer M; Schwab M Genome Biol; 2008 Oct; 9(10):R150. PubMed ID: 18851746 [TBL] [Abstract][Full Text] [Related]
8. Combined IFN-gamma and retinoic acid treatment targets the N-Myc/Max/Mad1 network resulting in repression of N-Myc target genes in MYCN-amplified neuroblastoma cells. Cetinkaya C; Hultquist A; Su Y; Wu S; Bahram F; Påhlman S; Guzhova I; Larsson LG Mol Cancer Ther; 2007 Oct; 6(10):2634-41. PubMed ID: 17938259 [TBL] [Abstract][Full Text] [Related]
9. Identification and pharmacological inactivation of the MYCN gene network as a therapeutic strategy for neuroblastic tumor cells. Chayka O; D'Acunto CW; Middleton O; Arab M; Sala A J Biol Chem; 2015 Jan; 290(4):2198-212. PubMed ID: 25477524 [TBL] [Abstract][Full Text] [Related]
10. The super elongation complex drives transcriptional addiction in Wang D; Yin Z; Wang H; Wang L; Li T; Xiao R; Xie T; Han R; Dong R; Liu H; Liang K; Qing G Sci Adv; 2023 Mar; 9(13):eadf0005. PubMed ID: 36989355 [No Abstract] [Full Text] [Related]
11. The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastoma. Lampis S; Raieli S; Montemurro L; Bartolucci D; Amadesi C; Bortolotti S; Angelucci S; Scardovi AL; Nieddu G; Cerisoli L; Paganelli F; Valente S; Fischer M; Martelli AM; Pasquinelli G; Pession A; Hrelia P; Tonelli R J Exp Clin Cancer Res; 2022 Apr; 41(1):160. PubMed ID: 35490242 [TBL] [Abstract][Full Text] [Related]
12. Spliceosomal vulnerability of MYCN-amplified neuroblastoma is contingent on PRMT5-mediated regulation of epitranscriptomic and metabolomic pathways. Bojko J; Kollareddy M; Szemes M; Bellamy J; Poon E; Moukachar A; Legge D; Vincent EE; Jones N; Malik S; Greenhough A; Paterson A; Park JH; Gallacher K; Chesler L; Malik K Cancer Lett; 2024 Nov; 604():217263. PubMed ID: 39313128 [TBL] [Abstract][Full Text] [Related]
13. Outcome of the p53-mediated DNA damage response in neuroblastoma is determined by morphological subtype and MYCN expression. Carr-Wilkinson J; Griffiths R; Elston R; Gamble LD; Goranov B; Redfern CP; Lunec J; Tweddle DA Cell Cycle; 2011 Nov; 10(21):3778-87. PubMed ID: 22052359 [TBL] [Abstract][Full Text] [Related]
14. Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma. Mills CM; Turner J; Piña IC; Garrabrant KA; Geerts D; Bachmann AS; Peterson YK; Woster PM Eur J Med Chem; 2022 Dec; 244():114818. PubMed ID: 36223680 [TBL] [Abstract][Full Text] [Related]
15. Functional interplay between MYCN, NCYM, and OCT4 promotes aggressiveness of human neuroblastomas. Kaneko Y; Suenaga Y; Islam SM; Matsumoto D; Nakamura Y; Ohira M; Yokoi S; Nakagawara A Cancer Sci; 2015 Jul; 106(7):840-7. PubMed ID: 25880909 [TBL] [Abstract][Full Text] [Related]
16. Human embryonic stem cell-derived neural crest model unveils CD55 as a cancer stem cell regulator for therapeutic targeting in MYCN-amplified neuroblastoma. Weng Z; Lin J; He J; Gao L; Lin S; Tsang LL; Zhang H; He X; Wang G; Yang X; Zhou H; Zhao H; Li G; Zou L; Jiang X Neuro Oncol; 2022 Jun; 24(6):872-885. PubMed ID: 34655293 [TBL] [Abstract][Full Text] [Related]
17. Association of heterogeneous MYCN amplification with clinical features, biological characteristics and outcomes in neuroblastoma: A report from the Children's Oncology Group. Campbell K; Naranjo A; Hibbitts E; Gastier-Foster JM; Bagatell R; Irwin MS; Shimada H; Hogarty M; Park JR; DuBois SG Eur J Cancer; 2020 Jul; 133():112-119. PubMed ID: 32492633 [TBL] [Abstract][Full Text] [Related]
18. Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma. Henriksen JR; Haug BH; Buechner J; Tømte E; Løkke C; Flaegstad T; Einvik C BMC Dev Biol; 2011 Jan; 11():1. PubMed ID: 21194500 [TBL] [Abstract][Full Text] [Related]
19. Biological effects of induced MYCN hyper-expression in MYCN-amplified neuroblastomas. Torres J; Regan PL; Edo R; Leonhardt P; Jeng EI; Rappaport EF; Ikegaki N; Tang XX Int J Oncol; 2010 Oct; 37(4):983-91. PubMed ID: 20811720 [TBL] [Abstract][Full Text] [Related]
20. GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3. Fabian J; Lodrini M; Oehme I; Schier MC; Thole TM; Hielscher T; Kopp-Schneider A; Opitz L; Capper D; von Deimling A; Wiegand I; Milde T; Mahlknecht U; Westermann F; Popanda O; Roels F; Hero B; Berthold F; Fischer M; Kulozik AE; Witt O; Deubzer HE Cancer Res; 2014 May; 74(9):2604-16. PubMed ID: 24419085 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]