BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 38512030)

  • 1. [leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) inhibits proliferation and promotes apoptosis of human HEL cells with JAK2 V617F mutation by blocking the JAK/STAT and PI3K/AKT signaling pathways].
    Fan C; Zhang Y; Yang R; Wu X; Zhou J; Xue J
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2024 Mar; 40(3):207-214. PubMed ID: 38512030
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual PI3K/AKT/mTOR inhibitor BEZ235 synergistically enhances the activity of JAK2 inhibitor against cultured and primary human myeloproliferative neoplasm cells.
    Fiskus W; Verstovsek S; Manshouri T; Smith JE; Peth K; Abhyankar S; McGuirk J; Bhalla KN
    Mol Cancer Ther; 2013 May; 12(5):577-88. PubMed ID: 23445613
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Curcumin induces apoptosis in JAK2-mutated cells by the inhibition of JAK2/STAT and mTORC1 pathways.
    Petiti J; Rosso V; Lo Iacono M; Panuzzo C; Calabrese C; Signorino E; Pironi L; Cartellà A; Bracco E; Pergolizzi B; Beltramo T; Fava C; Cilloni D
    J Cell Mol Med; 2019 Jun; 23(6):4349-4357. PubMed ID: 31033209
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel Compound, ND-17, Regulates the JAK/STAT, PI3K/AKT, and MAPK Pathways and Restrains Human T-lymphoid Leukemia Development.
    Ma W; Liu Y; Lei P; Zhu M; Pan X
    Curr Cancer Drug Targets; 2022; 22(5):404-413. PubMed ID: 35249489
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis.
    Winter PS; Sarosiek KA; Lin KH; Meggendorfer M; Schnittger S; Letai A; Wood KC
    Sci Signal; 2014 Dec; 7(357):ra122. PubMed ID: 25538080
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery and evaluation of ZT55, a novel highly-selective tyrosine kinase inhibitor of JAK2
    Hu M; Xu C; Yang C; Zuo H; Chen C; Zhang D; Shi G; Wang W; Shi J; Zhang T
    J Exp Clin Cancer Res; 2019 Feb; 38(1):49. PubMed ID: 30717771
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Akt activation through the phosphorylation of erythropoietin receptor at tyrosine 479 is required for myeloproliferative disorder-associated JAK2 V617F mutant-induced cellular transformation.
    Kamishimoto J; Tago K; Kasahara T; Funakoshi-Tago M
    Cell Signal; 2011 May; 23(5):849-56. PubMed ID: 21255641
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The JAK kinase inhibitor CP-690,550 suppresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation.
    Manshouri T; Quintás-Cardama A; Nussenzveig RH; Gaikwad A; Estrov Z; Prchal J; Cortes JE; Kantarjian HM; Verstovsek S
    Cancer Sci; 2008 Jun; 99(6):1265-73. PubMed ID: 18482053
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The multi-site docking protein Gab1 is constitutively phosphorylated independent from its recruitment to the plasma membrane in Jak2-V617F-positive cells and mediates proliferation of human erythroleukaemia cells.
    Bongartz H; Hessenkemper W; Müller C; Fensky M; Fritsch J; Mandel K; Behrmann I; Haan C; Fischer T; Feller SM; Schaper F
    Cell Signal; 2017 Jul; 35():37-47. PubMed ID: 28365441
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Convallatoxin promotes apoptosis and inhibits proliferation and angiogenesis through crosstalk between JAK2/STAT3 (T705) and mTOR/STAT3 (S727) signaling pathways in colorectal cancer.
    Zhang ZH; Li MY; Wang Z; Zuo HX; Wang JY; Xing Y; Jin C; Xu G; Piao L; Piao H; Ma J; Jin X
    Phytomedicine; 2020 Mar; 68():153172. PubMed ID: 32004989
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combined treatment with ruxolitinib and MK-2206 inhibits the JAK2/STAT5 and PI3K/AKT pathways via apoptosis in MDA-MB-231 breast cancer cell line.
    Guvenir Celik E; Eroglu O
    Mol Biol Rep; 2023 Jan; 50(1):319-329. PubMed ID: 36331743
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera.
    Nagao T; Kurosu T; Umezawa Y; Nogami A; Oshikawa G; Tohda S; Yamamoto M; Miura O
    PLoS One; 2014; 9(1):e84746. PubMed ID: 24404189
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Homoharringtonine affects the JAK2-STAT5 signal pathway through alteration of protein tyrosine kinase phosphorylation in acute myeloid leukemia cells.
    Tong H; Ren Y; Zhang F; Jin J
    Eur J Haematol; 2008 Oct; 81(4):259-66. PubMed ID: 18616510
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Naringin inhibits the proliferation and invasion of Eca109 esophageal cancer cells and promotes its apoptosis by blocking JAK/STAT signal pathway].
    Yang F; Jiang T; Zhang L; Qi Y; Yang Z
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2021 Dec; 37(12):1085-1091. PubMed ID: 34906296
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cardamomin protects from diabetes-induced kidney damage through modulating PI3K/AKT and JAK/STAT signaling pathways in rats.
    Gao C; Fei X; Wang M; Chen Q; Zhao N
    Int Immunopharmacol; 2022 Jun; 107():108610. PubMed ID: 35219163
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Concomitant inactivation of the epidermal growth factor receptor, phosphatidylinositol 3-kinase/Akt and Janus tyrosine kinase 2/signal transducer and activator of transcription 3 signalling pathways in cardiotoxin III-treated A549 cells.
    Su JC; Lin KL; Chien CM; Chuang PW; Chang LS; Lin SR
    Clin Exp Pharmacol Physiol; 2010 Aug; 37(8):833-40. PubMed ID: 20456425
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel mechanism of cannabidiol in suppressing ovarian cancer through LAIR-1 mediated mitochondrial dysfunction and apoptosis.
    Ma L; Zhang H; Liu C; Liu M; Shangguan F; Liu Y; Yang S; Li H; An J; Song S; Cao Q; Qu G
    Environ Toxicol; 2023 May; 38(5):1118-1132. PubMed ID: 36810933
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LAIR-1 suppresses cell growth of ovarian cancer cell via the PI3K-AKT-mTOR pathway.
    Liu Y; Ma L; Shangguan F; Zhao X; Wang W; Gao Z; Zhou H; Qu G; Huang Y; An J; Xue J; Yang S; Cao Q
    Aging (Albany NY); 2020 Sep; 12(16):16142-16154. PubMed ID: 32628130
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rationale for targeting the PI3K/Akt/mTOR pathway in myeloproliferative neoplasms.
    Bartalucci N; Guglielmelli P; Vannucchi AM
    Clin Lymphoma Myeloma Leuk; 2013 Sep; 13 Suppl 2():S307-9. PubMed ID: 24290217
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [The impact of autophagy on proliferation of HEL cells and hematopoietic cells of polycythemia vera patients with JAK2 V617F mutation].
    Dong L; Shen X; Wei W; Shi W; Zhang G; Cao W; Li D
    Zhonghua Xue Ye Xue Za Zhi; 2015 Jun; 36(6):520-5. PubMed ID: 26134021
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.