127 related articles for article (PubMed ID: 38518638)
1. Emodin-8-O-β-D-glucopyranoside-induced hepatotoxicity and gender differences in zebrafish as revealed by integration of metabolomics and transcriptomics.
Han T; Xu W; Wang X; Gao J; Zhang S; Yang L; Wang M; Li C; Li X
Phytomedicine; 2024 Jun; 128():155411. PubMed ID: 38518638
[TBL] [Abstract][Full Text] [Related]
2. In vivo hepatotoxicity screening of different extracts, components, and constituents of Polygoni Multiflori Thunb. in zebrafish (Danio rerio) larvae.
Li HY; Yang JB; Li WF; Qiu CX; Hu G; Wang ST; Song YF; Gao HY; Liu Y; Wang Q; Wang Y; Cheng XL; Wei F; Jin HT; Ma SC
Biomed Pharmacother; 2020 Nov; 131():110524. PubMed ID: 33152900
[TBL] [Abstract][Full Text] [Related]
3. Pharmacokinetic studies unveiled the drug-drug interaction between trans-2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucopyranoside and emodin that may contribute to the idiosyncratic hepatotoxicity of Polygoni Multiflori Radix.
Xing Y; Wang L; Wang C; Zhang Y; Zhang Y; Hu L; Gao X; Han L; Yang W
J Pharm Biomed Anal; 2019 Feb; 164():672-680. PubMed ID: 30472586
[TBL] [Abstract][Full Text] [Related]
4. Hepatotoxicity or hepatoprotection of emodin? Two sides of the same coin by
Ruan L; Jiang L; Zhao W; Meng H; Zheng Q; Wang J
Toxicol Appl Pharmacol; 2021 Nov; 431():115734. PubMed ID: 34606778
[TBL] [Abstract][Full Text] [Related]
5. Components synergy between stilbenes and emodin derivatives contributes to hepatotoxicity induced by
Zhang L; Liu X; Tu C; Li C; Song D; Zhu J; Zhou Y; Wang X; Li R; Xiao X; Liu Y; Wang J
Xenobiotica; 2020 May; 50(5):515-525. PubMed ID: 31424332
[No Abstract] [Full Text] [Related]
6. Discovery of Hepatotoxic Equivalent Markers and Mechanism of
Zhang Y; Liu L; Feng M; Wu H; Dai Y; Jia Z; Fang C; Liu M; Yan X; Zhu M; Huang B; Qu B; Xiao H
Molecules; 2022 Dec; 28(1):. PubMed ID: 36615221
[No Abstract] [Full Text] [Related]
7. [Study on potential hepatotoxicity of main monomers of Polygonum multiflorum based on liver micro-tissue].
Wang Q; Zhang QH; Wen HR; Guo HX; Zhang LS; Ma SC
Zhongguo Zhong Yao Za Zhi; 2020 Jun; 45(12):2954-2959. PubMed ID: 32627472
[TBL] [Abstract][Full Text] [Related]
8. Integrated spatially resolved metabolomics and network toxicology to investigate the hepatotoxicity mechanisms of component D of Polygonum multiflorum Thunb.
Jiang HY; Gao HY; Li J; Zhou TY; Wang ST; Yang JB; Hao RR; Pang F; Wei F; Liu ZG; Kuang L; Ma SC; He JM; Jin HT
J Ethnopharmacol; 2022 Nov; 298():115630. PubMed ID: 35987407
[TBL] [Abstract][Full Text] [Related]
9. Polygonum multiflorum Thunb. Induces hepatotoxicity in SD rats and hepatocyte spheroids by Disrupting the metabolism of bilirubin and bile acid.
Wang Q; Wen H; Ma S; Zhang Y
J Ethnopharmacol; 2022 Oct; 296():115461. PubMed ID: 35728710
[TBL] [Abstract][Full Text] [Related]
10. Hepatoxicity of major constituents and extractions of Radix Polygoni Multiflori and Radix Polygoni Multiflori Praeparata.
Yu J; Xie J; Mao XJ; Wang MJ; Li N; Wang J; Zhaori GT; Zhao RH
J Ethnopharmacol; 2011 Oct; 137(3):1291-9. PubMed ID: 21840387
[TBL] [Abstract][Full Text] [Related]
11. Hepatotoxic assessment of Polygoni Multiflori Radix extract and toxicokinetic study of stilbene glucoside and anthraquinones in rats.
Ma J; Zheng L; He YS; Li HJ
J Ethnopharmacol; 2015 Mar; 162():61-8. PubMed ID: 25557036
[TBL] [Abstract][Full Text] [Related]
12. 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside enhances the hepatotoxicity of emodin in vitro and in vivo.
Li D; Song Q; Ji X; Lyu Y; Lai YS; Zuo Z
Toxicol Lett; 2022 Jul; 365():74-85. PubMed ID: 35753641
[TBL] [Abstract][Full Text] [Related]
13. Reduction of emodin-8-O-ß-D-glucoside content participates in processing-based detoxification of polygoni multiflori radix.
Wang X; Zhao G; Ju C; Dong L; Liu Y; Ding Z; Li W; Peng Y; Zheng J
Phytomedicine; 2023 Jun; 114():154750. PubMed ID: 36990007
[TBL] [Abstract][Full Text] [Related]
14. Exploration of components and mechanisms of Polygoni Multiflori Radix-induced hepatotoxicity using siRNA -mediated CYP3A4 or UGT1A1 knockdown liver cells.
Hu YH; Li DK; Quan ZY; Wang CY; Zhou M; Sun ZX
J Ethnopharmacol; 2021 Apr; 270():113845. PubMed ID: 33485974
[TBL] [Abstract][Full Text] [Related]
15. Investigation of the idiosyncratic hepatotoxicity of Polygonum multiflorum Thunb. through metabolomics using GC-MS.
Lin Y; Xiao R; Xia BH; Zhang ZM; Li C; Wu P; Liao DF; Lin LM
BMC Complement Med Ther; 2021 Apr; 21(1):120. PubMed ID: 33845816
[TBL] [Abstract][Full Text] [Related]
16. Hepatotoxicity evaluation of Euphorbia kansui on zebrafish larvae in vivo.
Zhao C; Jia Z; Li E; Zhao X; Han T; Tian J; Li F; Zou D; Lin R
Phytomedicine; 2019 Sep; 62():152959. PubMed ID: 31132752
[TBL] [Abstract][Full Text] [Related]
17. [Exploration research on hepatotoxic constituents from Polygonum multiflorum root].
Yang M; Liu T; Feng WH; Hui LQ; Li RR; Liu XQ; Chen AJ; Li C; Wang ZM
Zhongguo Zhong Yao Za Zhi; 2016 Apr; 41(7):1289-1296. PubMed ID: 28879745
[TBL] [Abstract][Full Text] [Related]
18. Enhanced absorption and inhibited metabolism of emodin by 2, 3, 5, 4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside: Possible mechanisms for Polygoni Multiflori Radix-induced liver injury.
Yu Q; Jiang LL; Luo N; Fan YX; Ma J; Li P; Li HJ
Chin J Nat Med; 2017 Jun; 15(6):451-457. PubMed ID: 28629535
[TBL] [Abstract][Full Text] [Related]
19. Integration of transcriptomics and metabolomics profiling reveals the metabolic pathways affected in dictamnine-induced hepatotoxicity in mice.
Li ZQ; Wang LL; Zhou J; Zheng X; Jiang Y; Li P; Li HJ
J Proteomics; 2020 Feb; 213():103603. PubMed ID: 31812602
[TBL] [Abstract][Full Text] [Related]
20. Gender Differences in the Hepatotoxicity and Toxicokinetics of Emodin: The Potential Mechanisms Mediated by UGT2B7 and MRP2.
Wu L; Han W; Chen Y; Zhang T; Liu J; Zhong S; Liu H; Han C; Zhang Z; Liu S; Tang L
Mol Pharm; 2018 Sep; 15(9):3931-3945. PubMed ID: 30011215
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]