These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 38519575)

  • 21. Mycolactone A vs. B: Multiscale Simulations Reveal the Roles of Localization and Association in Isomer-Specific Toxicity.
    Nguyen JDM; da Hora GCA; Swanson JMJ
    Toxins (Basel); 2023 Aug; 15(8):. PubMed ID: 37624243
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Mechanism of Protein Translocation by the Sec61 Translocon Complex.
    Itskanov S; Park E
    Cold Spring Harb Perspect Biol; 2023 Jan; 15(1):. PubMed ID: 35940906
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The signal peptide as a new target for drug design.
    Lumangtad LA; Bell TW
    Bioorg Med Chem Lett; 2020 May; 30(10):127115. PubMed ID: 32209293
    [TBL] [Abstract][Full Text] [Related]  

  • 24. TRAM1 protein may support ER protein import by modulating the phospholipid bilayer near the lateral gate of the Sec61-channel.
    Klein MC; Lerner M; Nguyen D; Pfeffer S; Dudek J; Förster F; Helms V; Lang S; Zimmermann R
    Channels (Austin); 2020 Dec; 14(1):28-44. PubMed ID: 32013668
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Identification of signal peptide features for substrate specificity in human Sec62/Sec63-dependent ER protein import.
    Schorr S; Nguyen D; Haßdenteufel S; Nagaraj N; Cavalié A; Greiner M; Weissgerber P; Loi M; Paton AW; Paton JC; Molinari M; Förster F; Dudek J; Lang S; Helms V; Zimmermann R
    FEBS J; 2020 Nov; 287(21):4612-4640. PubMed ID: 32133789
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon.
    von der Malsburg K; Shao S; Hegde RS
    Mol Biol Cell; 2015 Jun; 26(12):2168-80. PubMed ID: 25877867
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Diastereomers of Coibamide A Show Altered Sec61 Client Selectivity and Ligand-Dependent Activity against Patient-Derived Glioma Stem-like Cells.
    Mattos DR; Neves WD; Kitamura T; Pradhan R; Wan X; da Hora CC; Tranter D; Kazemi S; Yu X; Tripathy N; Paavilainen VO; McPhail KL; Oishi S; Badr CE; Ishmael JE
    ACS Pharmacol Transl Sci; 2024 Jun; 7(6):1823-1838. PubMed ID: 38898945
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Signal Peptide Features Determining the Substrate Specificities of Targeting and Translocation Components in Human ER Protein Import.
    Lang S; Nguyen D; Bhadra P; Jung M; Helms V; Zimmermann R
    Front Physiol; 2022; 13():833540. PubMed ID: 35899032
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Interaction mapping of the Sec61 translocon identifies two Sec61α regions interacting with hydrophobic segments in translocating chains.
    Kida Y; Sakaguchi M
    J Biol Chem; 2018 Nov; 293(44):17050-17060. PubMed ID: 30213864
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Structural and functional profiling of the lateral gate of the Sec61 translocon.
    Reithinger JH; Yim C; Kim S; Lee H; Kim H
    J Biol Chem; 2014 May; 289(22):15845-55. PubMed ID: 24753257
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Copper inhibits protein maturation in the secretory pathway by targeting the Sec61 translocon in Saccharomyces cerevisiae.
    Saha N; Tomar RS
    J Biol Chem; 2022 Aug; 298(8):102170. PubMed ID: 35738397
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Mechanistic insights into the inhibition of Sec61-dependent co- and post-translational translocation by mycolactone.
    McKenna M; Simmonds RE; High S
    J Cell Sci; 2016 Apr; 129(7):1404-15. PubMed ID: 26869228
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Defining a conformational consensus motif in cotransin-sensitive signal sequences: a proteomic and site-directed mutagenesis study.
    Klein W; Westendorf C; Schmidt A; Conill-Cortés M; Rutz C; Blohs M; Beyermann M; Protze J; Krause G; Krause E; Schülein R
    PLoS One; 2015; 10(3):e0120886. PubMed ID: 25806945
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The Sec61/SecY complex is inherently deficient in translocating intrinsically disordered proteins.
    Gonsberg A; Jung S; Ulbrich S; Origi A; Ziska A; Baier M; Koch HG; Zimmermann R; Winklhofer KF; Tatzelt J
    J Biol Chem; 2017 Dec; 292(52):21383-21396. PubMed ID: 29084847
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Inhibitors of the Sec61 Complex and Novel High Throughput Screening Strategies to Target the Protein Translocation Pathway.
    Pauwels E; Schülein R; Vermeire K
    Int J Mol Sci; 2021 Nov; 22(21):. PubMed ID: 34769437
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway.
    Klein W; Rutz C; Eckhard J; Provinciael B; Specker E; Neuenschwander M; Kleinau G; Scheerer P; von Kries JP; Nazaré M; Vermeire K; Schülein R
    PLoS One; 2018; 13(12):e0208641. PubMed ID: 30543669
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Conserved motifs on the cytoplasmic face of the protein translocation channel are critical for the transition between resting and active conformations.
    Mandon EC; Butova C; Lachapelle A; Gilmore R
    J Biol Chem; 2018 Aug; 293(35):13662-13672. PubMed ID: 29986881
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Structure of the native Sec61 protein-conducting channel.
    Pfeffer S; Burbaum L; Unverdorben P; Pech M; Chen Y; Zimmermann R; Beckmann R; Förster F
    Nat Commun; 2015 Sep; 6():8403. PubMed ID: 26411746
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Membrane translocation at the ER: with a little help from my friends.
    O'Keefe S; High S
    FEBS J; 2020 Nov; 287(21):4607-4611. PubMed ID: 32301242
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Active and passive displacement of transmembrane domains both occur during opsin biogenesis at the Sec61 translocon.
    Ismail N; Crawshaw SG; High S
    J Cell Sci; 2006 Jul; 119(Pt 13):2826-36. PubMed ID: 16787949
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.