122 related articles for article (PubMed ID: 38520049)
1. Pharmacological degradation of ATR induces antiproliferative DNA replication stress in leukemic cells.
Kansy AG; Ashry R; Mustafa AM; Alfayomy AM; Radsak MP; Zeyn Y; Bros M; Sippl W; Krämer OH
Mol Oncol; 2024 Mar; ():. PubMed ID: 38520049
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, and biological characterization of proteolysis targeting chimera (PROTACs) for the ataxia telangiectasia and RAD3-related (ATR) kinase.
Alfayomy AM; Ashry R; Kansy AG; Sarnow AC; Erdmann F; Schmidt M; Krämer OH; Sippl W
Eur J Med Chem; 2024 Mar; 267():116167. PubMed ID: 38308949
[TBL] [Abstract][Full Text] [Related]
3. Adefovir dipivoxil induces DNA replication stress and augments ATR inhibitor-related cytotoxicity.
Patel A; Seraia E; Ebner D; Ryan AJ
Int J Cancer; 2020 Sep; 147(5):1474-1484. PubMed ID: 32159854
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of Wee1 sensitizes AML cells to ATR inhibitor VE-822-induced DNA damage and apoptosis.
Qi W; Xu X; Wang M; Li X; Wang C; Sun L; Zhao D; Sun L
Biochem Pharmacol; 2019 Jun; 164():273-282. PubMed ID: 31014753
[TBL] [Abstract][Full Text] [Related]
5. Protein kinase ATR inhibits E3 ubiquitin ligase CRL4
Bao W; Zhang W; Huang Y; Zhao Y; Wu C; Duan L; Wang L; Yan S
Cell Rep; 2023 Jul; 42(7):112685. PubMed ID: 37354461
[TBL] [Abstract][Full Text] [Related]
6. S-phase-dependent p50/NF-кB1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability.
Crawley CD; Kang S; Bernal GM; Wahlstrom JS; Voce DJ; Cahill KE; Garofalo A; Raleigh DR; Weichselbaum RR; Yamini B
Cell Cycle; 2015; 14(4):566-76. PubMed ID: 25590437
[TBL] [Abstract][Full Text] [Related]
7. A
Xu YJ; Khan S; Didier AC; Wozniak M; Liu Y; Singh A; Nakamura TM
Mol Cell Biol; 2019 Oct; 39(20):. PubMed ID: 31332096
[TBL] [Abstract][Full Text] [Related]
8. ZEB1 inhibition sensitizes cells to the ATR inhibitor VE-821 by abrogating epithelial-mesenchymal transition and enhancing DNA damage.
Song N; Jing W; Li C; Bai M; Cheng Y; Li H; Hou K; Li Y; Wang K; Li Z; Liu Y; Qu X; Che X
Cell Cycle; 2018; 17(5):595-604. PubMed ID: 29157079
[TBL] [Abstract][Full Text] [Related]
9. SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.
Jo U; Murai Y; Chakka S; Chen L; Cheng K; Murai J; Saha LK; Miller Jenkins LM; Pommier Y
Proc Natl Acad Sci U S A; 2021 Feb; 118(6):. PubMed ID: 33536335
[TBL] [Abstract][Full Text] [Related]
10. The SUMO (Small Ubiquitin-like Modifier) Ligase PIAS3 Primes ATR for Checkpoint Activation.
Wu CS; Zou L
J Biol Chem; 2016 Jan; 291(1):279-90. PubMed ID: 26565033
[TBL] [Abstract][Full Text] [Related]
11. 3F-Box protein 32 degrades ataxia telangiectasia and Rad3-related and regulates DNA damage response induced by gemcitabine in pancreatic cancer.
Yang C; Fan P; Zhu S; Yang H; Jin X; Wu H
Oncol Lett; 2018 Jun; 15(6):8878-8884. PubMed ID: 29805624
[TBL] [Abstract][Full Text] [Related]
12. Synergistic lethality between auranofin-induced oxidative DNA damage and ATR inhibition in cancer cells.
Zhang S; Zhao Y; Wang X; Qi C; Tian J; Zou Z
Life Sci; 2023 Nov; 332():122131. PubMed ID: 37778414
[TBL] [Abstract][Full Text] [Related]
13. Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation.
Martin L; Rainey M; Santocanale C; Gardner LB
Oncogene; 2012 Sep; 31(36):4076-84. PubMed ID: 22179839
[TBL] [Abstract][Full Text] [Related]
14. Exploring the ATR-CHK1 pathway in the response of doxorubicin-induced DNA damages in acute lymphoblastic leukemia cells.
Ghelli Luserna Di Rorà A; Ghetti M; Ledda L; Ferrari A; Bocconcelli M; Padella A; Napolitano R; Fontana MC; Liverani C; Imbrogno E; Bochicchio MT; Paganelli M; Robustelli V; Sanogo S; Cerchione C; Fumagalli M; Rondoni M; Imovilli A; Musuraca G; Martinelli G; Simonetti G
Cell Biol Toxicol; 2023 Jun; 39(3):795-811. PubMed ID: 34519926
[TBL] [Abstract][Full Text] [Related]
15. ATR phosphorylates SMARCAL1 to prevent replication fork collapse.
Couch FB; Bansbach CE; Driscoll R; Luzwick JW; Glick GG; Bétous R; Carroll CM; Jung SY; Qin J; Cimprich KA; Cortez D
Genes Dev; 2013 Jul; 27(14):1610-23. PubMed ID: 23873943
[TBL] [Abstract][Full Text] [Related]
16. Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint.
Lee AY; Chiba T; Truong LN; Cheng AN; Do J; Cho MJ; Chen L; Wu X
J Biol Chem; 2012 Jan; 287(4):2531-43. PubMed ID: 22123827
[TBL] [Abstract][Full Text] [Related]
17. Phosphorylation of the BRCA1 C terminus (BRCT) repeat inhibitor of hTERT (BRIT1) protein coordinates TopBP1 protein recruitment and amplifies ataxia telangiectasia-mutated and Rad3-related (ATR) Signaling.
Zhang B; Wang E; Dai H; Shen J; Hsieh HJ; Lu X; Peng G
J Biol Chem; 2014 Dec; 289(49):34284-95. PubMed ID: 25301947
[TBL] [Abstract][Full Text] [Related]
18. UV-induced ataxia-telangiectasia-mutated and Rad3-related (ATR) activation requires replication stress.
Ward IM; Minn K; Chen J
J Biol Chem; 2004 Mar; 279(11):9677-80. PubMed ID: 14742437
[TBL] [Abstract][Full Text] [Related]
19. Marek's Disease Virus Disables the ATR-Chk1 Pathway by Activating STAT3.
Lian X; Bao C; Li X; Zhang X; Chen H; Jung YS; Qian Y
J Virol; 2019 May; 93(9):. PubMed ID: 30787154
[TBL] [Abstract][Full Text] [Related]
20. A clinically relevant heterozygous ATR mutation sensitizes colorectal cancer cells to replication stress.
Egger T; Bordignon B; Coquelle A
Sci Rep; 2022 Mar; 12(1):5422. PubMed ID: 35361811
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]