BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 38520407)

  • 1. APLF facilitates interstrand DNA crosslink repair and replication fork protection to confer cisplatin resistance.
    Wu CK; Shiu JL; Wu CL; Hung CF; Ho YC; Chen YT; Tung SY; Yeh CF; Shen CH; Liaw H; Su WP
    Nucleic Acids Res; 2024 Jun; 52(10):5676-5697. PubMed ID: 38520407
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Replication fork stability confers chemoresistance in BRCA-deficient cells.
    Ray Chaudhuri A; Callen E; Ding X; Gogola E; Duarte AA; Lee JE; Wong N; Lafarga V; Calvo JA; Panzarino NJ; John S; Day A; Crespo AV; Shen B; Starnes LM; de Ruiter JR; Daniel JA; Konstantinopoulos PA; Cortez D; Cantor SB; Fernandez-Capetillo O; Ge K; Jonkers J; Rottenberg S; Sharan SK; Nussenzweig A
    Nature; 2016 Jul; 535(7612):382-7. PubMed ID: 27443740
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Preventing over-resection by DNA2 helicase/nuclease suppresses repair defects in Fanconi anemia cells.
    Karanja KK; Lee EH; Hendrickson EA; Campbell JL
    Cell Cycle; 2014; 13(10):1540-50. PubMed ID: 24626199
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CtIP mediates replication fork recovery in a FANCD2-regulated manner.
    Yeo JE; Lee EH; Hendrickson EA; Sobeck A
    Hum Mol Genet; 2014 Jul; 23(14):3695-705. PubMed ID: 24556218
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FANCD2-controlled chromatin access of the Fanconi-associated nuclease FAN1 is crucial for the recovery of stalled replication forks.
    Chaudhury I; Stroik DR; Sobeck A
    Mol Cell Biol; 2014 Nov; 34(21):3939-54. PubMed ID: 25135477
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness.
    Richter C; Marquardt S; Li F; Spitschak A; Murr N; Edelhäuser BAH; Iliakis G; Pützer BM; Logotheti S
    J Exp Clin Cancer Res; 2019 Jul; 38(1):292. PubMed ID: 31287003
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair.
    Fenton AL; Shirodkar P; Macrae CJ; Meng L; Koch CA
    Nucleic Acids Res; 2013 Apr; 41(7):4080-92. PubMed ID: 23449221
    [TBL] [Abstract][Full Text] [Related]  

  • 8. APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks.
    Iles N; Rulten S; El-Khamisy SF; Caldecott KW
    Mol Cell Biol; 2007 May; 27(10):3793-803. PubMed ID: 17353262
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability.
    Liu W; Polaczek P; Roubal I; Meng Y; Choe WC; Caron MC; Sedgeman CA; Xi Y; Liu C; Wu Q; Zheng L; Masson JY; Shen B; Campbell JL
    Nucleic Acids Res; 2023 Sep; 51(17):9144-9165. PubMed ID: 37526271
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.
    Hammel M; Yu Y; Radhakrishnan SK; Chokshi C; Tsai MS; Matsumoto Y; Kuzdovich M; Remesh SG; Fang S; Tomkinson AE; Lees-Miller SP; Tainer JA
    J Biol Chem; 2016 Dec; 291(53):26987-27006. PubMed ID: 27875301
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links.
    Rickman KA; Noonan RJ; Lach FP; Sridhar S; Wang AT; Abhyankar A; Huang A; Kelly M; Auerbach AD; Smogorzewska A
    Genes Dev; 2020 Jun; 34(11-12):832-846. PubMed ID: 32354836
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells.
    Batenburg NL; Mersaoui SY; Walker JR; Coulombe Y; Hammond-Martel I; Wurtele H; Masson JY; Zhu XD
    Nucleic Acids Res; 2021 Dec; 49(22):12836-12854. PubMed ID: 34871413
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells.
    Okamoto Y; Abe M; Mu A; Tempaku Y; Rogers CB; Mochizuki AL; Katsuki Y; Kanemaki MT; Takaori-Kondo A; Sobeck A; Bielinsky AK; Takata M
    Blood; 2021 Jan; 137(3):336-348. PubMed ID: 32735670
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2'-deoxycytidine and 5-hydroxymethyl-2'-deoxyuridine.
    Peña-Gómez MJ; Moreno-Gordillo P; Narmontė M; García-Calderón CB; Rukšėnaitė A; Klimašauskas S; Rosado IV
    Cell Death Dis; 2022 May; 13(5):503. PubMed ID: 35624090
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RADX Modulates RAD51 Activity to Control Replication Fork Protection.
    Bhat KP; Krishnamoorthy A; Dungrawala H; Garcin EB; Modesti M; Cortez D
    Cell Rep; 2018 Jul; 24(3):538-545. PubMed ID: 30021152
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response.
    Li GY; McCulloch RD; Fenton AL; Cheung M; Meng L; Ikura M; Koch CA
    Proc Natl Acad Sci U S A; 2010 May; 107(20):9129-34. PubMed ID: 20439749
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification and functional characterization of a Ku-binding motif in aprataxin polynucleotide kinase/phosphatase-like factor (APLF).
    Shirodkar P; Fenton AL; Meng L; Koch CA
    J Biol Chem; 2013 Jul; 288(27):19604-13. PubMed ID: 23689425
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RADX prevents genome instability by confining replication fork reversal to stalled forks.
    Krishnamoorthy A; Jackson J; Mohamed T; Adolph M; Vindigni A; Cortez D
    Mol Cell; 2021 Jul; 81(14):3007-3017.e5. PubMed ID: 34107305
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest.
    Singh M; Hunt CR; Pandita RK; Kumar R; Yang CR; Horikoshi N; Bachoo R; Serag S; Story MD; Shay JW; Powell SN; Gupta A; Jeffery J; Pandita S; Chen BP; Deckbar D; Löbrich M; Yang Q; Khanna KK; Worman HJ; Pandita TK
    Mol Cell Biol; 2013 Mar; 33(6):1210-22. PubMed ID: 23319047
    [TBL] [Abstract][Full Text] [Related]  

  • 20. APLF promotes the assembly and activity of non-homologous end joining protein complexes.
    Grundy GJ; Rulten SL; Zeng Z; Arribas-Bosacoma R; Iles N; Manley K; Oliver A; Caldecott KW
    EMBO J; 2013 Jan; 32(1):112-25. PubMed ID: 23178593
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.