BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 38553134)

  • 1. Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells.
    Ma Y; Okuda S; Okanishi H; Xu M; Jin C; Endou H; Ohgaki R; Kanai Y
    J Pharmacol Sci; 2024 May; 155(1):14-20. PubMed ID: 38553134
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation.
    Quan L; Ohgaki R; Hara S; Okuda S; Wei L; Okanishi H; Nagamori S; Endou H; Kanai Y
    J Exp Clin Cancer Res; 2020 Nov; 39(1):266. PubMed ID: 33256804
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Relationship between LAT1 expression and resistance to chemotherapy in pancreatic ductal adenocarcinoma.
    Altan B; Kaira K; Watanabe A; Kubo N; Bao P; Dolgormaa G; Bilguun EO; Araki K; Kanai Y; Yokobori T; Oyama T; Nishiyama M; Kuwano H; Shirabe K
    Cancer Chemother Pharmacol; 2018 Jan; 81(1):141-153. PubMed ID: 29149426
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of the amino-acid transporter LAT1 demonstrates anti-neoplastic activity in medulloblastoma.
    Cormerais Y; Pagnuzzi-Boncompagni M; Schrötter S; Giuliano S; Tambutté E; Endou H; Wempe MF; Pagès G; Pouysségur J; Picco V
    J Cell Mol Med; 2019 Apr; 23(4):2711-2718. PubMed ID: 30784173
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells.
    Nishikubo K; Ohgaki R; Okanishi H; Okuda S; Xu M; Endou H; Kanai Y
    J Cell Mol Med; 2022 Oct; 26(20):5246-5256. PubMed ID: 36071551
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5).
    Cormerais Y; Massard PA; Vucetic M; Giuliano S; Tambutté E; Durivault J; Vial V; Endou H; Wempe MF; Parks SK; Pouyssegur J
    J Biol Chem; 2018 Feb; 293(8):2877-2887. PubMed ID: 29326164
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combination effects of amino acid transporter LAT1 inhibitor nanvuranlat and cytotoxic anticancer drug gemcitabine on pancreatic and biliary tract cancer cells.
    Nishikubo K; Ohgaki R; Liu X; Okanishi H; Xu M; Endou H; Kanai Y
    Cancer Cell Int; 2023 Jun; 23(1):116. PubMed ID: 37322479
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression.
    Wang Q; Bailey CG; Ng C; Tiffen J; Thoeng A; Minhas V; Lehman ML; Hendy SC; Buchanan G; Nelson CC; Rasko JE; Holst J
    Cancer Res; 2011 Dec; 71(24):7525-36. PubMed ID: 22007000
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective Inhibition of L-type Amino Acid Transporter 1 Suppresses Cell Proliferation in Ovarian Clear Cell Carcinoma.
    Sekine M; Koh I; Nakamoto K; Nosaka S; Tomono K; Sugimoto J; Kudo Y
    Anticancer Res; 2023 Jun; 43(6):2509-2517. PubMed ID: 37247931
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer.
    Martinez RS; Salji MJ; Rushworth L; Ntala C; Rodriguez Blanco G; Hedley A; Clark W; Peixoto P; Hervouet E; Renaude E; Kung SHY; Galbraith LCA; Nixon C; Lilla S; MacKay GM; Fazli L; Gaughan L; Sumpton D; Gleave ME; Zanivan S; Blomme A; Leung HY
    Cancer Res; 2021 Jul; 81(13):3664-3678. PubMed ID: 33985973
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GZD824 Inhibits GCN2 and Sensitizes Cancer Cells to Amino Acid Starvation Stress.
    Kato Y; Kunimasa K; Takahashi M; Harada A; Nagasawa I; Osawa M; Sugimoto Y; Tomida A
    Mol Pharmacol; 2020 Dec; 98(6):669-676. PubMed ID: 33033108
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High expression of L-type amino acid transporter 1 (LAT1) predicts poor prognosis in pancreatic ductal adenocarcinomas.
    Yanagisawa N; Ichinoe M; Mikami T; Nakada N; Hana K; Koizumi W; Endou H; Okayasu I
    J Clin Pathol; 2012 Nov; 65(11):1019-23. PubMed ID: 22813728
    [TBL] [Abstract][Full Text] [Related]  

  • 13. LAT1 acts as a crucial transporter of amino acids in human thymic carcinoma cells.
    Hayashi K; Jutabha P; Maeda S; Supak Y; Ouchi M; Endou H; Fujita T; Chida M; Anzai N
    J Pharmacol Sci; 2016 Nov; 132(3):201-204. PubMed ID: 27567475
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models.
    Shi Z; Kaneda-Nakashima K; Ohgaki R; Xu M; Okanishi H; Endou H; Nagamori S; Kanai Y
    Sci Rep; 2023 Aug; 13(1):13943. PubMed ID: 37626086
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prognostic significance of L-type amino-acid transporter 1 expression in surgically resected pancreatic cancer.
    Kaira K; Sunose Y; Arakawa K; Ogawa T; Sunaga N; Shimizu K; Tominaga H; Oriuchi N; Itoh H; Nagamori S; Kanai Y; Segawa A; Furuya M; Mori M; Oyama T; Takeyoshi I
    Br J Cancer; 2012 Aug; 107(4):632-8. PubMed ID: 22805328
    [TBL] [Abstract][Full Text] [Related]  

  • 16. GCN2- and eIF2α-phosphorylation-independent, but ATF4-dependent, induction of CARE-containing genes in methionine-deficient cells.
    Mazor KM; Stipanuk MH
    Amino Acids; 2016 Dec; 48(12):2831-2842. PubMed ID: 27613409
    [TBL] [Abstract][Full Text] [Related]  

  • 17. c-Myc is crucial for the expression of LAT1 in MIA Paca-2 human pancreatic cancer cells.
    Hayashi K; Jutabha P; Endou H; Anzai N
    Oncol Rep; 2012 Sep; 28(3):862-6. PubMed ID: 22736142
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor.
    Okanishi H; Ohgaki R; Okuda S; Endou H; Kanai Y
    Cancer Sci; 2021 Feb; 112(2):871-883. PubMed ID: 33264461
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Up-Regulation of LAT1 during Antiandrogen Therapy Contributes to Progression in Prostate Cancer Cells.
    Xu M; Sakamoto S; Matsushima J; Kimura T; Ueda T; Mizokami A; Kanai Y; Ichikawa T
    J Urol; 2016 May; 195(5):1588-1597. PubMed ID: 26682754
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma.
    Palam LR; Gore J; Craven KE; Wilson JL; Korc M
    Cell Death Dis; 2015 Oct; 6(10):e1913. PubMed ID: 26469962
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.