These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 38557779)

  • 21. An analog of glibenclamide selectively enhances autophagic degradation of misfolded α1-antitrypsin Z.
    Wang Y; Cobanoglu MC; Li J; Hidvegi T; Hale P; Ewing M; Chu AS; Gong Z; Muzumdar R; Pak SC; Silverman GA; Bahar I; Perlmutter DH
    PLoS One; 2019; 14(1):e0209748. PubMed ID: 30673724
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The multiple causes of alpha1-antitrypsin deficiency.
    Lieberman J
    Pathol Biol (Paris); 1975 Sep; 23(7):517-20. PubMed ID: 1101153
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The significance of the F variant of alpha-1-antitrypsin and unique case report of a PiFF homozygote.
    Sinden NJ; Koura F; Stockley RA
    BMC Pulm Med; 2014 Aug; 14():132. PubMed ID: 25098359
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Deficiency Mutations of Alpha-1 Antitrypsin. Effects on Folding, Function, and Polymerization.
    Haq I; Irving JA; Saleh AD; Dron L; Regan-Mochrie GL; Motamedi-Shad N; Hurst JR; Gooptu B; Lomas DA
    Am J Respir Cell Mol Biol; 2016 Jan; 54(1):71-80. PubMed ID: 26091018
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Alpha-1-antitrypsin deficiency in children: liver disease is not reflected by low serum levels of alpha-1-antitrypsin - a study on 48 pediatric patients.
    Lang T; Mühlbauer M; Strobelt M; Weidinger S; Hadorn HB
    Eur J Med Res; 2005 Dec; 10(12):509-14. PubMed ID: 16356865
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Antioxidant Responses are Crucial for Defense against Misfolded Human Z-Type α
    Im H; Lim J
    Protein Pept Lett; 2022; 29(5):384-391. PubMed ID: 35319354
    [TBL] [Abstract][Full Text] [Related]  

  • 27. FBG1 Is the Final Arbitrator of A1AT-Z Degradation.
    Wen JH; Wen H; Gibson-Corley KN; Glenn KA
    PLoS One; 2015; 10(8):e0135591. PubMed ID: 26295339
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A lag in intracellular degradation of mutant alpha 1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ alpha 1-antitrypsin deficiency.
    Wu Y; Whitman I; Molmenti E; Moore K; Hippenmeyer P; Perlmutter DH
    Proc Natl Acad Sci U S A; 1994 Sep; 91(19):9014-8. PubMed ID: 8090762
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Heteropolymerization of S, I, and Z alpha1-antitrypsin and liver cirrhosis.
    Mahadeva R; Chang WS; Dafforn TR; Oakley DJ; Foreman RC; Calvin J; Wight DG; Lomas DA
    J Clin Invest; 1999 Apr; 103(7):999-1006. PubMed ID: 10194472
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover.
    Long OS; Benson JA; Kwak JH; Luke CJ; Gosai SJ; O'Reilly LP; Wang Y; Li J; Vetica AC; Miedel MT; Stolz DB; Watkins SC; Züchner S; Perlmutter DH; Silverman GA; Pak SC
    Hum Mol Genet; 2014 Oct; 23(19):5109-22. PubMed ID: 24838286
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The mechanism of Z alpha 1-antitrypsin accumulation in the liver.
    Lomas DA; Evans DL; Finch JT; Carrell RW
    Nature; 1992 Jun; 357(6379):605-7. PubMed ID: 1608473
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency.
    Burrows JA; Willis LK; Perlmutter DH
    Proc Natl Acad Sci U S A; 2000 Feb; 97(4):1796-801. PubMed ID: 10677536
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A new deficient variant of alpha1-antitrypsin (MDUARTE). Inability to detect the heterozygous state by antitrypsin phenotyping.
    Lieberman J; Gaidulis L; Klotz SD
    Am Rev Respir Dis; 1976 Jan; 113(1):31-6. PubMed ID: 1082282
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Three new alpha1-antitrypsin deficiency variants help to define a C-terminal region regulating conformational change and polymerization.
    Fra AM; Gooptu B; Ferrarotti I; Miranda E; Scabini R; Ronzoni R; Benini F; Corda L; Medicina D; Luisetti M; Schiaffonati L
    PLoS One; 2012; 7(6):e38405. PubMed ID: 22723858
    [TBL] [Abstract][Full Text] [Related]  

  • 35. CHOP and c-JUN up-regulate the mutant Z α
    Attanasio S; Ferriero R; Gernoux G; De Cegli R; Carissimo A; Nusco E; Campione S; Teckman J; Mueller C; Piccolo P; Brunetti-Pierri N
    J Biol Chem; 2020 Sep; 295(38):13213-13223. PubMed ID: 32723872
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Grp78, Grp94, and Grp170 interact with alpha1-antitrypsin mutants that are retained in the endoplasmic reticulum.
    Schmidt BZ; Perlmutter DH
    Am J Physiol Gastrointest Liver Physiol; 2005 Sep; 289(3):G444-55. PubMed ID: 15845869
    [TBL] [Abstract][Full Text] [Related]  

  • 37. hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α
    Segeritz CP; Rashid ST; de Brito MC; Serra MP; Ordonez A; Morell CM; Kaserman JE; Madrigal P; Hannan NRF; Gatto L; Tan L; Wilson AA; Lilley K; Marciniak SJ; Gooptu B; Lomas DA; Vallier L
    J Hepatol; 2018 Oct; 69(4):851-860. PubMed ID: 29879455
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Rapid PCR real-time genotyping of M-Malton alpha1-antitrypsin deficiency alleles by molecular beacons.
    Orrù G; Faa G; Pillai S; Pilloni L; Montaldo C; Pusceddu G; Piras V; Coni P
    Diagn Mol Pathol; 2005 Dec; 14(4):237-42. PubMed ID: 16319694
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Hepatic fibrosis and carcinogenesis in α1-antitrypsin deficiency: a prototype for chronic tissue damage in gain-of-function disorders.
    Perlmutter DH; Silverman GA
    Cold Spring Harb Perspect Biol; 2011 Mar; 3(3):. PubMed ID: 21421920
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Protein Misfolding and Aggregation: The Relatedness between Parkinson's Disease and Hepatic Endoplasmic Reticulum Storage Disorders.
    Padilla-Godínez FJ; Ramos-Acevedo R; Martínez-Becerril HA; Bernal-Conde LD; Garrido-Figueroa JF; Hiriart M; Hernández-López A; Argüero-Sánchez R; Callea F; Guerra-Crespo M
    Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830348
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.