177 related articles for article (PubMed ID: 38559310)
1. Discovery of the Highly Selective and Potent STAT3 Inhibitor for Pancreatic Cancer Treatment.
Chen H; Bian A; Zhou W; Miao Y; Ye J; Li J; He P; Zhang Q; Sun Y; Sun Z; Ti C; Chen Y; Yi Z; Liu M
ACS Cent Sci; 2024 Mar; 10(3):579-594. PubMed ID: 38559310
[TBL] [Abstract][Full Text] [Related]
2. Selectively Targeting STAT3 Using a Small Molecule Inhibitor is a Potential Therapeutic Strategy for Pancreatic Cancer.
Chen H; Zhou W; Bian A; Zhang Q; Miao Y; Yin X; Ye J; Xu S; Ti C; Sun Z; Zheng J; Chen Y; Liu M; Yi Z
Clin Cancer Res; 2023 Feb; 29(4):815-830. PubMed ID: 36374556
[TBL] [Abstract][Full Text] [Related]
3. Phospho-Ser727 triggers a multistep inactivation of STAT3 by rapid dissociation of pY705-SH2 through C-terminal tail modulation.
Yang J; Kunimoto H; Katayama B; Zhao H; Shiromizu T; Wang L; Ozawa T; Tomonaga T; Tsuruta D; Nakajima K
Int Immunol; 2020 Feb; 32(2):73-88. PubMed ID: 31555812
[TBL] [Abstract][Full Text] [Related]
4. Preclinical characterization of WB737, a potent and selective STAT3 inhibitor, in natural killer/T-cell lymphoma.
Wang Y; Zhou W; Chen J; Chen J; Deng P; Chen H; Sun Y; Yu Z; Pang D; Liu L; Wang P; Hong JH; Teh BT; Huang H; Li W; Yi Z; Lim ST; Chen Y; Ong CK; Liu M; Tan J
MedComm (2020); 2023 Aug; 4(4):e284. PubMed ID: 37334274
[TBL] [Abstract][Full Text] [Related]
5. Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice.
Blaskovich MA; Sun J; Cantor A; Turkson J; Jove R; Sebti SM
Cancer Res; 2003 Mar; 63(6):1270-9. PubMed ID: 12649187
[TBL] [Abstract][Full Text] [Related]
6. Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells.
Shin DS; Kim HN; Shin KD; Yoon YJ; Kim SJ; Han DC; Kwon BM
Cancer Res; 2009 Jan; 69(1):193-202. PubMed ID: 19118003
[TBL] [Abstract][Full Text] [Related]
7. Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors.
Cai G; Yu W; Song D; Zhang W; Guo J; Zhu J; Ren Y; Kong L
Eur J Med Chem; 2019 Jul; 174():236-251. PubMed ID: 31048139
[TBL] [Abstract][Full Text] [Related]
8. Ethanol inhibition of angiotensin II-stimulated Tyr705 and Ser727 STAT3 phosphorylation in cultured rat hepatocytes: relevance to activation of p42/44 mitogen-activated protein kinase.
Weng YI; Aroor AR; Shukla SD
Alcohol; 2008 Aug; 42(5):397-406. PubMed ID: 18411006
[TBL] [Abstract][Full Text] [Related]
9. Role and regulation of STAT3 phosphorylation at Ser727 in melanocytes and melanoma cells.
Sakaguchi M; Oka M; Iwasaki T; Fukami Y; Nishigori C
J Invest Dermatol; 2012 Jul; 132(7):1877-85. PubMed ID: 22418867
[TBL] [Abstract][Full Text] [Related]
10. Potent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3.
Mandal PK; Gao F; Lu Z; Ren Z; Ramesh R; Birtwistle JS; Kaluarachchi KK; Chen X; Bast RC; Liao WS; McMurray JS
J Med Chem; 2011 May; 54(10):3549-63. PubMed ID: 21486047
[TBL] [Abstract][Full Text] [Related]
11. Structure-based discovery of potent and selective small-molecule inhibitors targeting signal transducer and activator of transcription 3 (STAT3).
Huang Q; Zhong Y; Li B; Ouyang S; Deng L; Mo J; Shi S; Lv N; Wu R; Liu P; Hu W; Zhang X; Wang Y
Eur J Med Chem; 2021 Oct; 221():113525. PubMed ID: 34000483
[TBL] [Abstract][Full Text] [Related]
12. A cell-permeable Stat3 SH2 domain mimetic inhibits Stat3 activation and induces antitumor cell effects in vitro.
Zhao W; Jaganathan S; Turkson J
J Biol Chem; 2010 Nov; 285(46):35855-65. PubMed ID: 20807764
[TBL] [Abstract][Full Text] [Related]
13. Farnesyl transferase inhibitor (R115777)-induced inhibition of STAT3(Tyr705) phosphorylation in human pancreatic cancer cell lines require extracellular signal-regulated kinases.
Venkatasubbarao K; Choudary A; Freeman JW
Cancer Res; 2005 Apr; 65(7):2861-71. PubMed ID: 15805288
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of STAT3 Tyr705 phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells.
Zhao S; Venkatasubbarao K; Lazor JW; Sperry J; Jin C; Cao L; Freeman JW
Cancer Res; 2008 Jun; 68(11):4221-8. PubMed ID: 18519681
[TBL] [Abstract][Full Text] [Related]
15. Discovery of a Highly Potent and Orally Bioavailable STAT3 Dual Phosphorylation Inhibitor for Pancreatic Cancer Treatment.
He P; Bian A; Miao Y; Jin W; Chen H; He J; Li L; Sun Y; Ye J; Liu M; Yi Z; Zhou W; Chen Y
J Med Chem; 2022 Nov; 65(22):15487-15511. PubMed ID: 36282975
[TBL] [Abstract][Full Text] [Related]
16. Structure-Activity Studies of Phosphopeptidomimetic Prodrugs Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 3 (Stat3).
Mandal PK; Ren Z; Chen X; Kaluarachchi K; Liao WS; McMurray JS
Int J Pept Res Ther; 2013 Mar; 19(1):3-12. PubMed ID: 24707243
[TBL] [Abstract][Full Text] [Related]
17. Constitutively active Galpha16 stimulates STAT3 via a c-Src/JAK- and ERK-dependent mechanism.
Lo RK; Cheung H; Wong YH
J Biol Chem; 2003 Dec; 278(52):52154-65. PubMed ID: 14551213
[TBL] [Abstract][Full Text] [Related]
18. A phosphopeptide mimetic prodrug targeting the SH2 domain of Stat3 inhibits tumor growth and angiogenesis.
Auzenne EJ; Klostergaard J; Mandal PK; Liao WS; Lu Z; Gao F; Bast RC; Robertson FM; McMurray JS
J Exp Ther Oncol; 2012; 10(2):155-62. PubMed ID: 23350355
[TBL] [Abstract][Full Text] [Related]
19. Dual inhibition of MYC and SLC39A10 by a novel natural product STAT3 inhibitor derived from Chaetomium globosum suppresses tumor growth and metastasis in gastric cancer.
Guan X; Yang J; Wang W; Zhao B; Hu S; Yu D; Yuan L; Shi Y; Xu J; Dong J; Wang J; Cheng XD; Qin JJ
Pharmacol Res; 2023 Mar; 189():106703. PubMed ID: 36804016
[TBL] [Abstract][Full Text] [Related]
20. LL1, a novel and highly selective STAT3 inhibitor, displays anti-colorectal cancer activities in vitro and in vivo.
Liu Z; Wang H; Guan L; Lai C; Yu W; Lai M
Br J Pharmacol; 2020 Jan; 177(2):298-313. PubMed ID: 31499589
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
