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22. Quantitative correlation of homogeneously stained regions on chromosome 10 with dihydrofolate reductase enzyme in human cells. Wolman SR; Craven ML; Grill SP; Domin BA; Cheng YC Proc Natl Acad Sci U S A; 1983 Feb; 80(3):807-9. PubMed ID: 6572370 [TBL] [Abstract][Full Text] [Related]
23. A study of chromosomal changes associated with amplified dihydrofolate reductase genes in rat hepatoma cells and their dedifferentiated variants. Fougere-Deschatrette C; Schimke RT; Weil D; Weiss MC J Cell Biol; 1984 Aug; 99(2):497-502. PubMed ID: 6746737 [TBL] [Abstract][Full Text] [Related]
24. Gene amplification and drug resistance in mammalian cells. Schimke RT; Brown PC; Kaufman RJ Natl Cancer Inst Monogr; 1982; 60():79-86. PubMed ID: 7121575 [TBL] [Abstract][Full Text] [Related]
25. Isolation and characterization of a variant dihydrofolate reductase cDNA from methotrexate-resistant murine L5178Y cells. McIvor RS; Simonsen CC Nucleic Acids Res; 1990 Dec; 18(23):7025-32. PubMed ID: 2263462 [TBL] [Abstract][Full Text] [Related]
26. Methotrexate resistance and double minutes in a cell line from the SEWA mouse ascites tumor. Martinsson T; Tenning P; Lundh L; Levan G Hereditas; 1982; 97(1):123-37. PubMed ID: 7129936 [No Abstract] [Full Text] [Related]
27. Correlation of double-minute chromosomes with unstable multidrug cross-resistance in uptake mutants of neuroblastoma cells. Baskin F; Rosenberg RN; Dev V Proc Natl Acad Sci U S A; 1981 Jun; 78(6):3654-8. PubMed ID: 6943568 [TBL] [Abstract][Full Text] [Related]
28. The mosquito dihydrofolate reductase gene functions as a dominant selectable marker in transfected cells. Shotkoski FA; Fallon AM Insect Biochem Mol Biol; 1993 Dec; 23(8):883-93. PubMed ID: 8220387 [TBL] [Abstract][Full Text] [Related]
29. Mathematical models of gene amplification with applications to cellular drug resistance and tumorigenicity. Kimmel M; Axelrod DE Genetics; 1990 Jul; 125(3):633-44. PubMed ID: 2379824 [TBL] [Abstract][Full Text] [Related]
30. Selective killing of methotrexate-resistant cells carrying amplified dihydrofolate reductase genes. Urlaub G; Landzberg M; Chasin LA Cancer Res; 1981 May; 41(5):1594-601. PubMed ID: 7194140 [TBL] [Abstract][Full Text] [Related]
31. Loss of unstably amplified dihydrofolate reductase genes from mouse cells is greatly accelerated by hydroxyurea. Snapka RM; Varshavsky A Proc Natl Acad Sci U S A; 1983 Dec; 80(24):7533-7. PubMed ID: 6584871 [TBL] [Abstract][Full Text] [Related]
32. Chromatin organization in the homogeneously staining regions of a methotrexate-resistant mouse cell line: interspersion of inactive and active chromatin domains distinguished by acetylation of histone H4. Nicol L; Jeppesen P J Cell Sci; 1996 Sep; 109 ( Pt 9)():2221-8. PubMed ID: 8886973 [TBL] [Abstract][Full Text] [Related]
33. Double minute chromosomes in mouse methotrexate-resistant cells studied by atomic force microscopy. Deng X; Zhang L; Zhang Y; Yan Y; Xu Z; Dong S; Fu S Biochem Biophys Res Commun; 2006 Aug; 346(4):1228-33. PubMed ID: 16806082 [TBL] [Abstract][Full Text] [Related]
34. Differential sensitivity of double minute chromosomes to hydroxyurea treatment in cultured methotrexate-resistant mouse cells. Nevaldine BH; Rizwana R; Hahn PJ Mutat Res; 1999 Aug; 406(2-4):55-62. PubMed ID: 10479722 [TBL] [Abstract][Full Text] [Related]
35. Human dihydrofolate reductase gene is located in chromosome 5 and is unlinked to the related pseudogenes. Maurer BJ; Barker PE; Masters JN; Ruddle FH; Attardi G Proc Natl Acad Sci U S A; 1984 Mar; 81(5):1484-8. PubMed ID: 6584893 [TBL] [Abstract][Full Text] [Related]
36. Transformation of mouse fibroblasts to methotrexate resistance by a recombinant plasmid expressing a prokaryotic dihydrofolate reductase. O'Hare K; Benoist C; Breathnach R Proc Natl Acad Sci U S A; 1981 Mar; 78(3):1527-31. PubMed ID: 6262811 [TBL] [Abstract][Full Text] [Related]
37. Early appearance and long-term persistence of the submicroscopic extrachromosomal elements (amplisomes) containing the amplified DHFR genes in human cell lines. Pauletti G; Lai E; Attardi G Proc Natl Acad Sci U S A; 1990 Apr; 87(8):2955-9. PubMed ID: 2326258 [TBL] [Abstract][Full Text] [Related]
38. Cytogenetic analysis of chimeric antibody-producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure. Kim SJ; Lee GM Biotechnol Bioeng; 1999 Sep; 64(6):741-9. PubMed ID: 10417224 [TBL] [Abstract][Full Text] [Related]
39. Systemic resistance to methotrexate in transgenic mice carrying a mutant dihydrofolate reductase gene. Isola LM; Gordon JW Proc Natl Acad Sci U S A; 1986 Dec; 83(24):9621-5. PubMed ID: 3467329 [TBL] [Abstract][Full Text] [Related]