212 related articles for article (PubMed ID: 38565249)
1. A germline point mutation in the MYC-FBW7 phosphodegron initiates hematopoietic malignancies.
Freie B; Carroll PA; Varnum-Finney BJ; Ramsey EL; Ramani V; Bernstein I; Eisenman RN
Genes Dev; 2024 Apr; 38(5-6):253-272. PubMed ID: 38565249
[TBL] [Abstract][Full Text] [Related]
2. A Germline Point Mutation in the MYC-FBW7 Phosphodegron Initiates Hematopoietic Malignancies.
Freie B; Carroll PA; Varnum-Finney BJ; Ramani V; Bernstein I; Eisenman RN
bioRxiv; 2023 Oct; ():. PubMed ID: 37961183
[TBL] [Abstract][Full Text] [Related]
3. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
Welcker M; Orian A; Jin J; Grim JE; Harper JW; Eisenman RN; Clurman BE
Proc Natl Acad Sci U S A; 2004 Jun; 101(24):9085-90. PubMed ID: 15150404
[TBL] [Abstract][Full Text] [Related]
4. Triggering Fbw7-mediated proteasomal degradation of c-Myc by oridonin induces cell growth inhibition and apoptosis.
Huang HL; Weng HY; Wang LQ; Yu CH; Huang QJ; Zhao PP; Wen JZ; Zhou H; Qu LH
Mol Cancer Ther; 2012 May; 11(5):1155-65. PubMed ID: 22389469
[TBL] [Abstract][Full Text] [Related]
5. T-cell Dysfunction upon Expression of MYC with Altered Phosphorylation at Threonine 58 and Serine 62.
Daniel CJ; Pelz C; Wang X; Munks MW; Ko A; Murugan D; Byers SA; Juarez E; Taylor KL; Fan G; Coussens LM; Link JM; Sears RC
Mol Cancer Res; 2022 Jul; 20(7):1151-1165. PubMed ID: 35380701
[TBL] [Abstract][Full Text] [Related]
6. Zinc finger protein 746 promotes colorectal cancer progression via c-Myc stability mediated by glycogen synthase kinase 3β and F-box and WD repeat domain-containing 7.
Jung JH; Jung DB; Kim H; Lee H; Kang SE; Srivastava SK; Yun M; Kim SH
Oncogene; 2018 Jul; 37(27):3715-3728. PubMed ID: 29628506
[TBL] [Abstract][Full Text] [Related]
7. Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7.
Thompson BJ; Jankovic V; Gao J; Buonamici S; Vest A; Lee JM; Zavadil J; Nimer SD; Aifantis I
J Exp Med; 2008 Jun; 205(6):1395-408. PubMed ID: 18474632
[TBL] [Abstract][Full Text] [Related]
8. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
Nakajima T; Kitagawa K; Ohhata T; Sakai S; Uchida C; Shibata K; Minegishi N; Yumimoto K; Nakayama KI; Masumoto K; Katou F; Niida H; Kitagawa M
J Biol Chem; 2015 Apr; 290(16):10368-81. PubMed ID: 25670854
[TBL] [Abstract][Full Text] [Related]
9. The F-box protein FBXL16 up-regulates the stability of C-MYC oncoprotein by antagonizing the activity of the F-box protein FBW7.
Morel M; Shah KN; Long W
J Biol Chem; 2020 Jun; 295(23):7970-7980. PubMed ID: 32345600
[TBL] [Abstract][Full Text] [Related]
10. The Tumor Suppressor FBW7 and the Vitamin D Receptor Are Mutual Cofactors in Protein Turnover and Transcriptional Regulation.
Salehi-Tabar R; Memari B; Wong H; Dimitrov V; Rochel N; White JH
Mol Cancer Res; 2019 Mar; 17(3):709-719. PubMed ID: 30606768
[TBL] [Abstract][Full Text] [Related]
11. FBW7 (F-box and WD Repeat Domain-Containing 7) Negatively Regulates Glucose Metabolism by Targeting the c-Myc/TXNIP (Thioredoxin-Binding Protein) Axis in Pancreatic Cancer.
Ji S; Qin Y; Liang C; Huang R; Shi S; Liu J; Jin K; Liang D; Xu W; Zhang B; Liu L; Liu C; Xu J; Ni Q; Chiao PJ; Li M; Yu X
Clin Cancer Res; 2016 Aug; 22(15):3950-60. PubMed ID: 26983463
[TBL] [Abstract][Full Text] [Related]
12. Inositol pyrophosphates promote MYC polyubiquitination by FBW7 to regulate cell survival.
Lolla P; Shah A; Unnikannan CP; Oddi V; Bhandari R
Biochem J; 2021 Apr; 478(8):1647-1661. PubMed ID: 33821962
[TBL] [Abstract][Full Text] [Related]
13. MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7.
Xu Y; Sengupta T; Kukreja L; Minella AC
J Biol Chem; 2010 Nov; 285(45):34439-46. PubMed ID: 20826802
[TBL] [Abstract][Full Text] [Related]
14. Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation.
Siu KT; Xu Y; Swartz KL; Bhattacharyya M; Gurbuxani S; Hua Y; Minella AC
Mol Cell Biol; 2014 Sep; 34(17):3244-58. PubMed ID: 24958101
[TBL] [Abstract][Full Text] [Related]
15. Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance.
Campbell KJ; Bath ML; Turner ML; Vandenberg CJ; Bouillet P; Metcalf D; Scott CL; Cory S
Blood; 2010 Oct; 116(17):3197-207. PubMed ID: 20631380
[TBL] [Abstract][Full Text] [Related]
16. Stat5-deficient hematopoiesis is permissive for Myc-induced B-cell leukemogenesis.
Wang Z; Medrzycki M; Bunting ST; Bunting KD
Oncotarget; 2015 Oct; 6(30):28961-72. PubMed ID: 26338970
[TBL] [Abstract][Full Text] [Related]
17. The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability.
King B; Trimarchi T; Reavie L; Xu L; Mullenders J; Ntziachristos P; Aranda-Orgilles B; Perez-Garcia A; Shi J; Vakoc C; Sandy P; Shen SS; Ferrando A; Aifantis I
Cell; 2013 Jun; 153(7):1552-66. PubMed ID: 23791182
[TBL] [Abstract][Full Text] [Related]
18. Phosphorylation regulates c-Myc's oncogenic activity in the mammary gland.
Wang X; Cunningham M; Zhang X; Tokarz S; Laraway B; Troxell M; Sears RC
Cancer Res; 2011 Feb; 71(3):925-36. PubMed ID: 21266350
[TBL] [Abstract][Full Text] [Related]
19. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
Yada M; Hatakeyama S; Kamura T; Nishiyama M; Tsunematsu R; Imaki H; Ishida N; Okumura F; Nakayama K; Nakayama KI
EMBO J; 2004 May; 23(10):2116-25. PubMed ID: 15103331
[TBL] [Abstract][Full Text] [Related]
20. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation.
Wilson A; Murphy MJ; Oskarsson T; Kaloulis K; Bettess MD; Oser GM; Pasche AC; Knabenhans C; Macdonald HR; Trumpp A
Genes Dev; 2004 Nov; 18(22):2747-63. PubMed ID: 15545632
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
