167 related articles for article (PubMed ID: 38565696)
1. Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ.
Chen CL; Syahirah R; Ravala SK; Yen YC; Klose T; Deng Q; Tesmer JJG
Nat Struct Mol Biol; 2024 Apr; ():. PubMed ID: 38565696
[TBL] [Abstract][Full Text] [Related]
2. Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ.
Chen CL; Syahirah R; Ravala SK; Yen YC; Klose T; Deng Q; Tesmer JJG
bioRxiv; 2023 May; ():. PubMed ID: 37205329
[TBL] [Abstract][Full Text] [Related]
3. Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity.
Shymanets A; Prajwal ; Vadas O; Czupalla C; LoPiccolo J; Brenowitz M; Ghigo A; Hirsch E; Krause E; Wetzker R; Williams RL; Harteneck C; Nürnberg B
Biochem J; 2015 Jul; 469(1):59-69. PubMed ID: 26173259
[TBL] [Abstract][Full Text] [Related]
4. Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs.
Rathinaswamy MK; Jenkins ML; Duewell BR; Zhang X; Harris NJ; Evans JT; Stariha JTB; Dalwadi U; Fleming KD; Ranga-Prasad H; Yip CK; Williams RL; Hansen SD; Burke JE
Cell Rep; 2023 Mar; 42(3):112172. PubMed ID: 36842083
[TBL] [Abstract][Full Text] [Related]
5. Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs).
Vadas O; Dbouk HA; Shymanets A; Perisic O; Burke JE; Abi Saab WF; Khalil BD; Harteneck C; Bresnick AR; Nürnberg B; Backer JM; Williams RL
Proc Natl Acad Sci U S A; 2013 Nov; 110(47):18862-7. PubMed ID: 24190998
[TBL] [Abstract][Full Text] [Related]
6. Gβγ is a direct regulator of endogenous p101/p110γ and p84/p110γ PI3Kγ complexes in mouse neutrophils.
Rynkiewicz NK; Anderson KE; Suire S; Collins DM; Karanasios E; Vadas O; Williams R; Oxley D; Clark J; Stephens LR; Hawkins PT
Sci Signal; 2020 Nov; 13(656):. PubMed ID: 33144519
[TBL] [Abstract][Full Text] [Related]
7. Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain.
Harris NJ; Jenkins ML; Nam SE; Rathinaswamy MK; Parson MAH; Ranga-Prasad H; Dalwadi U; Moeller BE; Sheeky E; Hansen SD; Yip CK; Burke JE
Elife; 2023 Jul; 12():. PubMed ID: 37417733
[TBL] [Abstract][Full Text] [Related]
8. Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain.
Harris NJ; Jenkins ML; Nam SE; Rathinaswamy MK; Parson MA; Ranga-Prasad H; Dalwadi U; Moeller BE; Sheekey E; Hansen SD; Yip CK; Burke JE
bioRxiv; 2023 May; ():. PubMed ID: 37090531
[TBL] [Abstract][Full Text] [Related]
9. Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation.
Rathinaswamy MK; Dalwadi U; Fleming KD; Adams C; Stariha JTB; Pardon E; Baek M; Vadas O; DiMaio F; Steyaert J; Hansen SD; Yip CK; Burke JE
Sci Adv; 2021 Aug; 7(35):. PubMed ID: 34452907
[TBL] [Abstract][Full Text] [Related]
10. Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gamma.
Kurig B; Shymanets A; Bohnacker T; Prajwal ; Brock C; Ahmadian MR; Schaefer M; Gohla A; Harteneck C; Wymann MP; Jeanclos E; Nürnberg B
Proc Natl Acad Sci U S A; 2009 Dec; 106(48):20312-7. PubMed ID: 19906996
[TBL] [Abstract][Full Text] [Related]
11. Roles of non-catalytic subunits in gbetagamma-induced activation of class I phosphoinositide 3-kinase isoforms beta and gamma.
Maier U; Babich A; Nürnberg B
J Biol Chem; 1999 Oct; 274(41):29311-7. PubMed ID: 10506190
[TBL] [Abstract][Full Text] [Related]
12. G protein βγ translocation to the Golgi apparatus activates MAPK via p110γ-p101 heterodimers.
Khater M; Wei Z; Xu X; Huang W; Lokeshwar BL; Lambert NA; Wu G
J Biol Chem; 2021; 296():100325. PubMed ID: 33493514
[TBL] [Abstract][Full Text] [Related]
13. p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma.
Suire S; Coadwell J; Ferguson GJ; Davidson K; Hawkins P; Stephens L
Curr Biol; 2005 Mar; 15(6):566-70. PubMed ID: 15797027
[TBL] [Abstract][Full Text] [Related]
14. Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma.
Voigt P; Brock C; Nürnberg B; Schaefer M
J Biol Chem; 2005 Feb; 280(6):5121-7. PubMed ID: 15611065
[TBL] [Abstract][Full Text] [Related]
15. The p101 subunit of PI3Kγ restores activation by Gβ mutants deficient in stimulating p110γ.
Shymanets A; Ahmadian MR; Kössmeier KT; Wetzker R; Harteneck C; Nürnberg B
Biochem J; 2012 Feb; 441(3):851-8. PubMed ID: 22054284
[TBL] [Abstract][Full Text] [Related]
16. Gbetagamma stimulates phosphoinositide 3-kinase-gamma by direct interaction with two domains of the catalytic p110 subunit.
Leopoldt D; Hanck T; Exner T; Maier U; Wetzker R; Nürnberg B
J Biol Chem; 1998 Mar; 273(12):7024-9. PubMed ID: 9507010
[TBL] [Abstract][Full Text] [Related]
17. Agonists cause nuclear translocation of phosphatidylinositol 3-kinase gamma. A Gbetagamma-dependent pathway that requires the p110gamma amino terminus.
Metjian A; Roll RL; Ma AD; Abrams CS
J Biol Chem; 1999 Sep; 274(39):27943-7. PubMed ID: 10488142
[TBL] [Abstract][Full Text] [Related]
18. p87 and p101 subunits are distinct regulators determining class IB phosphoinositide 3-kinase (PI3K) specificity.
Shymanets A; Prajwal ; Bucher K; Beer-Hammer S; Harteneck C; Nürnberg B
J Biol Chem; 2013 Oct; 288(43):31059-68. PubMed ID: 24014027
[TBL] [Abstract][Full Text] [Related]
19. Signal amplification between Gbetagamma release and PI3Kgamma-mediated PI(3,4,5)P3 formation monitored by a fluorescent Gbetagamma biosensor protein and repetitive two component total internal reflection/fluorescence redistribution after photobleaching analysis.
Tannert A; Voigt P; Burgold S; Tannert S; Schaefer M
Biochemistry; 2008 Oct; 47(43):11239-50. PubMed ID: 18831540
[TBL] [Abstract][Full Text] [Related]
20. PI3K
Jin JR; Gogvadze E; Xavier AR; Bohnacker T; Voelzmann J; Wymann MP
Front Immunol; 2020; 11():585070. PubMed ID: 33193405
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
