BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 38570351)

  • 21. In-Depth Characterization of mAb Charge Variants by On-Line Multidimensional Liquid Chromatography-Mass Spectrometry.
    Liu Z; Cao Y; Zhang L; Xu Y; Zhang Z
    Anal Chem; 2023 May; 95(20):7977-7984. PubMed ID: 37170561
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structural and Functional Analysis of CEX Fractions Collected from a Novel Avastin
    Gurel B; Berksoz M; Capkin E; Parlar A; Pala MC; Ozkan A; Capan Y; Daglikoca DE; Yuce M
    Pharmaceutics; 2022 Jul; 14(8):. PubMed ID: 36015197
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Characterization of recombinant monoclonal antibody charge variants using WCX chromatography, icIEF and LC-MS/MS.
    Liu H; Ren W; Zong L; Zhang J; Wang Y
    Anal Biochem; 2019 Jan; 564-565():1-12. PubMed ID: 30291836
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Characterization of a unique IgG1 mAb CEX profile by limited Lys-C proteolysis/CEX separation coupled with mass spectrometry and structural analysis.
    Kim J; Jones L; Taylor L; Kannan G; Jackson F; Lau H; Latypov RF; Bailey B
    J Chromatogr B Analyt Technol Biomed Life Sci; 2010 Jul; 878(22):1973-81. PubMed ID: 20554483
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Bridging size and charge variants of a therapeutic monoclonal antibody by two-dimensional liquid chromatography.
    Chen Z; Zeng M; Park SJ; Balakrishnan G; Zhou K; Pan D; Das TK
    J Pharm Biomed Anal; 2020 May; 183():113178. PubMed ID: 32086124
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Charge variants characterization of a monoclonal antibody by ion exchange chromatography coupled on-line to native mass spectrometry: Case study after a long-term storage at +5°C.
    Leblanc Y; Ramon C; Bihoreau N; Chevreux G
    J Chromatogr B Analyt Technol Biomed Life Sci; 2017 Mar; 1048():130-139. PubMed ID: 28242492
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Insights into the generation of monoclonal antibody acidic charge variants during Chinese hamster ovary cell cultures.
    Tang H; Miao S; Zhang X; Fan L; Liu X; Tan WS; Zhao L
    Appl Microbiol Biotechnol; 2018 Feb; 102(3):1203-1214. PubMed ID: 29238873
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Multidimensional LC-MS with
    Verscheure L; Detremmerie S; Stals H; De Vos J; Sandra P; Lynen F; Borgions F; Sandra K
    J Chromatogr A; 2024 Jul; 1726():464947. PubMed ID: 38724406
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Change of charge variant composition of trastuzumab upon stressing at physiological conditions.
    Spanov B; Olaleye O; Lingg N; Bentlage AEH; Govorukhina N; Hermans J; van de Merbel N; Vidarsson G; Jungbauer A; Bischoff R
    J Chromatogr A; 2021 Oct; 1655():462506. PubMed ID: 34492576
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Investigation of anomalous charge variant profile reveals discrete pH-dependent conformations and conformation-dependent charge states within the CDR3 loop of a therapeutic mAb.
    Lan W; Valente JJ; Ilott A; Chennamsetty N; Liu Z; Rizzo JM; Yamniuk AP; Qiu D; Shackman HM; Bolgar MS
    MAbs; 2020; 12(1):1763138. PubMed ID: 32432964
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Identification of multiple sources of the acidic charge variants in an IgG1 monoclonal antibody.
    Miao S; Xie P; Zou M; Fan L; Liu X; Zhou Y; Zhao L; Ding D; Wang H; Tan WS
    Appl Microbiol Biotechnol; 2017 Jul; 101(14):5627-5638. PubMed ID: 28439623
    [TBL] [Abstract][Full Text] [Related]  

  • 32. LC-MS Approach to Decipher a Light Chain Chromatographic Peak Splitting of a Monoclonal Antibody.
    Liu Y; VanAernum Z; Zhang Y; Gao X; Vlad M; Feng B; Cross R; Kilgore B; Newman A; Wang D; Schuessler HA; Richardson DD; Chadwick JS
    Pharm Res; 2023 Dec; 40(12):3087-3098. PubMed ID: 37936013
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Effects of carboxypeptidase B treatment and elevated temperature on recombinant monoclonal antibody charge variants in cation-exchange chromatography analysis.
    Kim DG; Kim HJ; Kim HJ
    Arch Pharm Res; 2016 Oct; 39(10):1472-1481. PubMed ID: 27522657
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Charge variant native mass spectrometry benefits mass precision and dynamic range of monoclonal antibody intact mass analysis.
    Bailey AO; Han G; Phung W; Gazis P; Sutton J; Josephs JL; Sandoval W
    MAbs; 2018; 10(8):1214-1225. PubMed ID: 30339478
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A competitive binding-mass spectrometry strategy for high-throughput evaluation of potential critical quality attributes of therapeutic monoclonal antibodies.
    Zhang Z; Yan Y; Wang S; Li N
    MAbs; 2022; 14(1):2133674. PubMed ID: 36224723
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Two-dimensional capillary zone electrophoresis-mass spectrometry for the characterization of intact monoclonal antibody charge variants, including deamidation products.
    Jooß K; Hühner J; Kiessig S; Moritz B; Neusüß C
    Anal Bioanal Chem; 2017 Oct; 409(26):6057-6067. PubMed ID: 28801824
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Characterization of the acidic species of a monoclonal antibody using weak cation exchange chromatography and LC-MS.
    Ponniah G; Kita A; Nowak C; Neill A; Kori Y; Rajendran S; Liu H
    Anal Chem; 2015 Sep; 87(17):9084-92. PubMed ID: 26222016
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Characterization of therapeutic proteins by cation exchange chromatography-mass spectrometry and top-down analysis.
    Shi RL; Xiao G; Dillon TM; Ricci MS; Bondarenko PV
    MAbs; 2020; 12(1):1739825. PubMed ID: 32292112
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Characterization of drug-product-related impurities and variants of a therapeutic monoclonal antibody by higher energy C-trap dissociation mass spectrometry.
    Wang D; Wynne C; Gu F; Becker C; Zhao J; Mueller HM; Li H; Shameem M; Liu YH
    Anal Chem; 2015 Jan; 87(2):914-21. PubMed ID: 25513708
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Pertuzumab Charge Variant Analysis and Complementarity-Determining Region Stability Assessment to Deamidation.
    Spanov B; Olaleye O; Mesurado T; Govorukhina N; Jungbauer A; van de Merbel NC; Lingg N; Bischoff R
    Anal Chem; 2023 Feb; 95(8):3951-3958. PubMed ID: 36795375
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.