81 related articles for article (PubMed ID: 38579724)
41. Insulator dysfunction and oncogene activation in IDH mutant gliomas.
Flavahan WA; Drier Y; Liau BB; Gillespie SM; Venteicher AS; Stemmer-Rachamimov AO; Suvà ML; Bernstein BE
Nature; 2016 Jan; 529(7584):110-4. PubMed ID: 26700815
[TBL] [Abstract][Full Text] [Related]
42. Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion.
Tateishi K; Wakimoto H; Iafrate AJ; Tanaka S; Loebel F; Lelic N; Wiederschain D; Bedel O; Deng G; Zhang B; He T; Shi X; Gerszten RE; Zhang Y; Yeh JJ; Curry WT; Zhao D; Sundaram S; Nigim F; Koerner MVA; Ho Q; Fisher DE; Roider EM; Kemeny LV; Samuels Y; Flaherty KT; Batchelor TT; Chi AS; Cahill DP
Cancer Cell; 2015 Dec; 28(6):773-784. PubMed ID: 26678339
[TBL] [Abstract][Full Text] [Related]
43. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma.
Patel AP; Tirosh I; Trombetta JJ; Shalek AK; Gillespie SM; Wakimoto H; Cahill DP; Nahed BV; Curry WT; Martuza RL; Louis DN; Rozenblatt-Rosen O; Suvà ML; Regev A; Bernstein BE
Science; 2014 Jun; 344(6190):1396-401. PubMed ID: 24925914
[TBL] [Abstract][Full Text] [Related]
44. Full-length RNA-seq from single cells using Smart-seq2.
Picelli S; Faridani OR; Björklund AK; Winberg G; Sagasser S; Sandberg R
Nat Protoc; 2014 Jan; 9(1):171-81. PubMed ID: 24385147
[TBL] [Abstract][Full Text] [Related]
45. Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation.
Wang F; Travins J; DeLaBarre B; Penard-Lacronique V; Schalm S; Hansen E; Straley K; Kernytsky A; Liu W; Gliser C; Yang H; Gross S; Artin E; Saada V; Mylonas E; Quivoron C; Popovici-Muller J; Saunders JO; Salituro FG; Yan S; Murray S; Wei W; Gao Y; Dang L; Dorsch M; Agresta S; Schenkein DP; Biller SA; Su SM; de Botton S; Yen KE
Science; 2013 May; 340(6132):622-6. PubMed ID: 23558173
[TBL] [Abstract][Full Text] [Related]
46. An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.
Rohle D; Popovici-Muller J; Palaskas N; Turcan S; Grommes C; Campos C; Tsoi J; Clark O; Oldrini B; Komisopoulou E; Kunii K; Pedraza A; Schalm S; Silverman L; Miller A; Wang F; Yang H; Chen Y; Kernytsky A; Rosenblum MK; Liu W; Biller SA; Su SM; Brennan CW; Chan TA; Graeber TG; Yen KE; Mellinghoff IK
Science; 2013 May; 340(6132):626-30. PubMed ID: 23558169
[TBL] [Abstract][Full Text] [Related]
47. IDH mutation impairs histone demethylation and results in a block to cell differentiation.
Lu C; Ward PS; Kapoor GS; Rohle D; Turcan S; Abdel-Wahab O; Edwards CR; Khanin R; Figueroa ME; Melnick A; Wellen KE; O'Rourke DM; Berger SL; Chan TA; Levine RL; Mellinghoff IK; Thompson CB
Nature; 2012 Feb; 483(7390):474-8. PubMed ID: 22343901
[TBL] [Abstract][Full Text] [Related]
48. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype.
Turcan S; Rohle D; Goenka A; Walsh LA; Fang F; Yilmaz E; Campos C; Fabius AW; Lu C; Ward PS; Thompson CB; Kaufman A; Guryanova O; Levine R; Heguy A; Viale A; Morris LG; Huse JT; Mellinghoff IK; Chan TA
Nature; 2012 Feb; 483(7390):479-83. PubMed ID: 22343889
[TBL] [Abstract][Full Text] [Related]
49. Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping.
Borger DR; Tanabe KK; Fan KC; Lopez HU; Fantin VR; Straley KS; Schenkein DP; Hezel AF; Ancukiewicz M; Liebman HM; Kwak EL; Clark JW; Ryan DP; Deshpande V; Dias-Santagata D; Ellisen LW; Zhu AX; Iafrate AJ
Oncologist; 2012; 17(1):72-9. PubMed ID: 22180306
[TBL] [Abstract][Full Text] [Related]
50. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome.
Li B; Dewey CN
BMC Bioinformatics; 2011 Aug; 12():323. PubMed ID: 21816040
[TBL] [Abstract][Full Text] [Related]
51. The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.
Chowdhury R; Yeoh KK; Tian YM; Hillringhaus L; Bagg EA; Rose NR; Leung IK; Li XS; Woon EC; Yang M; McDonough MA; King ON; Clifton IJ; Klose RJ; Claridge TD; Ratcliffe PJ; Schofield CJ; Kawamura A
EMBO Rep; 2011 May; 12(5):463-9. PubMed ID: 21460794
[TBL] [Abstract][Full Text] [Related]
52. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.
Xu W; Yang H; Liu Y; Yang Y; Wang P; Kim SH; Ito S; Yang C; Wang P; Xiao MT; Liu LX; Jiang WQ; Liu J; Zhang JY; Wang B; Frye S; Zhang Y; Xu YH; Lei QY; Guan KL; Zhao SM; Xiong Y
Cancer Cell; 2011 Jan; 19(1):17-30. PubMed ID: 21251613
[TBL] [Abstract][Full Text] [Related]
53. CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.
Zawadzka M; Rivers LE; Fancy SP; Zhao C; Tripathi R; Jamen F; Young K; Goncharevich A; Pohl H; Rizzi M; Rowitch DH; Kessaris N; Suter U; Richardson WD; Franklin RJ
Cell Stem Cell; 2010 Jun; 6(6):578-90. PubMed ID: 20569695
[TBL] [Abstract][Full Text] [Related]
54. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma.
Noushmehr H; Weisenberger DJ; Diefes K; Phillips HS; Pujara K; Berman BP; Pan F; Pelloski CE; Sulman EP; Bhat KP; Verhaak RG; Hoadley KA; Hayes DN; Perou CM; Schmidt HK; Ding L; Wilson RK; Van Den Berg D; Shen H; Bengtsson H; Neuvial P; Cope LM; Buckley J; Herman JG; Baylin SB; Laird PW; Aldape K;
Cancer Cell; 2010 May; 17(5):510-22. PubMed ID: 20399149
[TBL] [Abstract][Full Text] [Related]
55. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.
Ward PS; Patel J; Wise DR; Abdel-Wahab O; Bennett BD; Coller HA; Cross JR; Fantin VR; Hedvat CV; Perl AE; Rabinowitz JD; Carroll M; Su SM; Sharp KA; Levine RL; Thompson CB
Cancer Cell; 2010 Mar; 17(3):225-34. PubMed ID: 20171147
[TBL] [Abstract][Full Text] [Related]
56. Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations.
Gross S; Cairns RA; Minden MD; Driggers EM; Bittinger MA; Jang HG; Sasaki M; Jin S; Schenkein DP; Su SM; Dang L; Fantin VR; Mak TW
J Exp Med; 2010 Feb; 207(2):339-44. PubMed ID: 20142433
[TBL] [Abstract][Full Text] [Related]
57. Recurring mutations found by sequencing an acute myeloid leukemia genome.
Mardis ER; Ding L; Dooling DJ; Larson DE; McLellan MD; Chen K; Koboldt DC; Fulton RS; Delehaunty KD; McGrath SD; Fulton LA; Locke DP; Magrini VJ; Abbott RM; Vickery TL; Reed JS; Robinson JS; Wylie T; Smith SM; Carmichael L; Eldred JM; Harris CC; Walker J; Peck JB; Du F; Dukes AF; Sanderson GE; Brummett AM; Clark E; McMichael JF; Meyer RJ; Schindler JK; Pohl CS; Wallis JW; Shi X; Lin L; Schmidt H; Tang Y; Haipek C; Wiechert ME; Ivy JV; Kalicki J; Elliott G; Ries RE; Payton JE; Westervelt P; Tomasson MH; Watson MA; Baty J; Heath S; Shannon WD; Nagarajan R; Link DC; Walter MJ; Graubert TA; DiPersio JF; Wilson RK; Ley TJ
N Engl J Med; 2009 Sep; 361(11):1058-66. PubMed ID: 19657110
[TBL] [Abstract][Full Text] [Related]
58. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome.
Langmead B; Trapnell C; Pop M; Salzberg SL
Genome Biol; 2009; 10(3):R25. PubMed ID: 19261174
[TBL] [Abstract][Full Text] [Related]
59. IDH1 and IDH2 mutations in gliomas.
Yan H; Parsons DW; Jin G; McLendon R; Rasheed BA; Yuan W; Kos I; Batinic-Haberle I; Jones S; Riggins GJ; Friedman H; Friedman A; Reardon D; Herndon J; Kinzler KW; Velculescu VE; Vogelstein B; Bigner DD
N Engl J Med; 2009 Feb; 360(8):765-73. PubMed ID: 19228619
[TBL] [Abstract][Full Text] [Related]
60. An integrated genomic analysis of human glioblastoma multiforme.
Parsons DW; Jones S; Zhang X; Lin JC; Leary RJ; Angenendt P; Mankoo P; Carter H; Siu IM; Gallia GL; Olivi A; McLendon R; Rasheed BA; Keir S; Nikolskaya T; Nikolsky Y; Busam DA; Tekleab H; Diaz LA; Hartigan J; Smith DR; Strausberg RL; Marie SK; Shinjo SM; Yan H; Riggins GJ; Bigner DD; Karchin R; Papadopoulos N; Parmigiani G; Vogelstein B; Velculescu VE; Kinzler KW
Science; 2008 Sep; 321(5897):1807-12. PubMed ID: 18772396
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
