These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
152 related articles for article (PubMed ID: 38587937)
1. DeepP450: Predicting Human P450 Activities of Small Molecules by Integrating Pretrained Protein Language Model and Molecular Representation. Chang J; Fan X; Tian B J Chem Inf Model; 2024 Apr; 64(8):3149-3160. PubMed ID: 38587937 [TBL] [Abstract][Full Text] [Related]
2. CYPlebrity: Machine learning models for the prediction of inhibitors of cytochrome P450 enzymes. Plonka W; Stork C; Šícho M; Kirchmair J Bioorg Med Chem; 2021 Sep; 46():116388. PubMed ID: 34488021 [TBL] [Abstract][Full Text] [Related]
4. CYPstrate: A Set of Machine Learning Models for the Accurate Classification of Cytochrome P450 Enzyme Substrates and Non-Substrates. Holmer M; de Bruyn Kops C; Stork C; Kirchmair J Molecules; 2021 Aug; 26(15):. PubMed ID: 34361831 [TBL] [Abstract][Full Text] [Related]
5. Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries. Veith H; Southall N; Huang R; James T; Fayne D; Artemenko N; Shen M; Inglese J; Austin CP; Lloyd DG; Auld DS Nat Biotechnol; 2009 Nov; 27(11):1050-5. PubMed ID: 19855396 [TBL] [Abstract][Full Text] [Related]
6. Fluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug-Drug Interactions. He R; Dai Z; Finel M; Zhang F; Tu D; Yang L; Ge G Drug Metab Dispos; 2023 Oct; 51(10):1254-1272. PubMed ID: 37349113 [TBL] [Abstract][Full Text] [Related]
7. DR-predictor: incorporating flexible docking with specialized electronic reactivity and machine learning techniques to predict CYP-mediated sites of metabolism. Huang TW; Zaretzki J; Bergeron C; Bennett KP; Breneman CM J Chem Inf Model; 2013 Dec; 53(12):3352-66. PubMed ID: 24261543 [TBL] [Abstract][Full Text] [Related]
8. A Conserved Allosteric Site on Drug-Metabolizing CYPs: A Systematic Computational Assessment. Fischer A; Smieško M Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948012 [TBL] [Abstract][Full Text] [Related]
9. Classification Models for Predicting Cytochrome P450 Enzyme-Substrate Selectivity. Zhang T; Dai H; Liu LA; Lewis DF; Wei D Mol Inform; 2012 Jan; 31(1):53-62. PubMed ID: 27478177 [TBL] [Abstract][Full Text] [Related]
10. Inhibition and induction of cytochrome P450 and the clinical implications. Lin JH; Lu AY Clin Pharmacokinet; 1998 Nov; 35(5):361-90. PubMed ID: 9839089 [TBL] [Abstract][Full Text] [Related]
11. Cytochrome P450 enzymes and metabolism of drugs and neurotoxins within the mammalian brain. Stocco MR; Tyndale RF Adv Pharmacol; 2022; 95():73-106. PubMed ID: 35953164 [TBL] [Abstract][Full Text] [Related]
12. The impact of legacy and novel perfluoroalkyl substances on human cytochrome P450: An in vitro study on the inhibitory potential and underlying mechanisms. Amstutz VH; Cengo A; Sijm DTHM; Vrolijk MF Toxicology; 2022 Feb; 468():153116. PubMed ID: 35121066 [TBL] [Abstract][Full Text] [Related]
13. Structural insights into understudied human cytochrome P450 enzymes. Machalz D; Pach S; Bermudez M; Bureik M; Wolber G Drug Discov Today; 2021 Oct; 26(10):2456-2464. PubMed ID: 34161845 [TBL] [Abstract][Full Text] [Related]
14. Ferrous and ferric state of cytochromes P450 in intact Escherichia coli cells: a possible role of cytochrome P450-flavodoxin interactions. Culka M; Milichovsky J; Jerabek P; Stiborova M; Martinek V Neuro Endocrinol Lett; 2015; 36 Suppl 1():29-37. PubMed ID: 26757119 [TBL] [Abstract][Full Text] [Related]
15. Prediction of cytochrome P450-mediated drug clearance in humans based on the measured activities of selected CYPs. Gao J; Wang J; Gao N; Tian X; Zhou J; Fang Y; Zhang HF; Wen Q; Jia LJ; Zou D; Qiao HL Biosci Rep; 2017 Dec; 37(6):. PubMed ID: 29054967 [TBL] [Abstract][Full Text] [Related]