194 related articles for article (PubMed ID: 38589034)
1. Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype.
Nuechterlein N; Shelbourn A; Szulzewsky F; Arora S; Casad M; Pattwell S; Merino-Galan L; Sulman E; Arowa S; Alvinez N; Jung M; Brown D; Tang K; Jackson S; Stoica S; Chittaboina P; Banasavadi-Siddegowda YK; Wirsching HG; Stella N; Shapiro L; Paddison P; Patel AP; Gilbert MR; Abdullaev Z; Aldape K; Pratt D; Holland EC; Cimino PJ
Genes Dev; 2024 Apr; 38(5-6):273-288. PubMed ID: 38589034
[TBL] [Abstract][Full Text] [Related]
2. Implications for immunotherapy of tumor-mediated T-cell apoptosis associated with loss of the tumor suppressor PTEN in glioblastoma.
Waldron JS; Yang I; Han S; Tihan T; Sughrue ME; Mills SA; Pieper RO; Parsa AT
J Clin Neurosci; 2010 Dec; 17(12):1543-7. PubMed ID: 20822910
[TBL] [Abstract][Full Text] [Related]
3. RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN.
Park S; Zhao D; Hatanpaa KJ; Mickey BE; Saha D; Boothman DA; Story MD; Wong ET; Burma S; Georgescu MM; Rangnekar VM; Chauncey SS; Habib AA
Cancer Res; 2009 May; 69(10):4107-11. PubMed ID: 19435890
[TBL] [Abstract][Full Text] [Related]
4. Upregulation of PTEN in glioma cells by cord blood mesenchymal stem cells inhibits migration via downregulation of the PI3K/Akt pathway.
Dasari VR; Kaur K; Velpula KK; Gujrati M; Fassett D; Klopfenstein JD; Dinh DH; Rao JS
PLoS One; 2010 Apr; 5(4):e10350. PubMed ID: 20436671
[TBL] [Abstract][Full Text] [Related]
5. Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation.
Peterziel H; Müller J; Danner A; Barbus S; Liu HK; Radlwimmer B; Pietsch T; Lichter P; Schütz G; Hess J; Angel P
Neuro Oncol; 2012 Apr; 14(4):426-39. PubMed ID: 22394497
[TBL] [Abstract][Full Text] [Related]
6. Spinster homolog 2 reduces malignancies of glioblastoma via PTEN/PI3K/AKT pathway.
Liang W; Liu M; Su Y; Wen Y; Wang L; Shan J; Zhao J; Xie K; Wang J
IUBMB Life; 2024 Mar; 76(3):140-160. PubMed ID: 37728571
[TBL] [Abstract][Full Text] [Related]
7. Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma.
Koul D; Wang S; Wu S; Saito N; Zheng S; Gao F; Kaul I; Setoguchi M; Nakayama K; Koyama K; Shiose Y; Sulman EP; Hirota Y; Yung WKA
Oncotarget; 2017 Mar; 8(13):21741-21753. PubMed ID: 28423515
[TBL] [Abstract][Full Text] [Related]
8. MAGI3 Suppresses Glioma Cell Proliferation via Upregulation of PTEN Expression.
Ma Q; Zhang Y; Meng R; Xie KM; Xiong Y; Lin S; He ZL; Tao T; Yang Y; Zhao JZ; He JQ
Biomed Environ Sci; 2015 Jul; 28(7):502-9. PubMed ID: 26248734
[TBL] [Abstract][Full Text] [Related]
9. Combinatorial therapy with adenoviral-mediated PTEN and a PI3K inhibitor suppresses malignant glioma cell growth in vitro and in vivo by regulating the PI3K/AKT signaling pathway.
Nan Y; Guo L; Song Y; Wang L; Yu K; Huang Q; Zhong Y
J Cancer Res Clin Oncol; 2017 Aug; 143(8):1477-1487. PubMed ID: 28401302
[TBL] [Abstract][Full Text] [Related]
10. Common Genomic Aberrations in Mouse and Human Breast Cancers with Concurrent P53 Deficiency and Activated PTEN-PI3K-AKT Pathway.
Martinez JD; Mo Q; Xu Y; Qin L; Li Y; Xu J
Int J Biol Sci; 2022; 18(1):229-241. PubMed ID: 34975329
[TBL] [Abstract][Full Text] [Related]
11. Microrchidia family CW‑type zinc finger 2 promotes the proliferation, invasion, migration and epithelial‑mesenchymal transition of glioma by regulating PTEN/PI3K/AKT signaling via binding to N‑myc downstream regulated gene 1 promoter.
Zhang J; Yang Y; Dong Y; Liu C
Int J Mol Med; 2022 Feb; 49(2):. PubMed ID: 34913078
[TBL] [Abstract][Full Text] [Related]
12. The effect of miR-579 on the PI3K/AKT pathway in human glioblastoma PTEN mutant cell lines.
Kalhori MR; Irani S; Soleimani M; Arefian E; Kouhkan F
J Cell Biochem; 2019 Oct; 120(10):16760-16774. PubMed ID: 31243804
[TBL] [Abstract][Full Text] [Related]
13. Elevated ETV6 Expression in Glioma Promotes an Aggressive In Vitro Phenotype Associated with Shorter Patient Survival.
Xiong Z; Wu S; Li FJ; Luo C; Jin QY; Connolly ID; Hayden Gephart M; You L
Genes (Basel); 2022 Oct; 13(10):. PubMed ID: 36292767
[No Abstract] [Full Text] [Related]
14. MCL1 gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway.
Wu DM; Hong XW; Wen X; Han XR; Wang S; Wang YJ; Shen M; Fan SH; Zhuang J; Zhang ZF; Shan Q; Li MQ; Hu B; Sun CH; Lu J; Zheng YL
IUBMB Life; 2019 Jan; 71(1):81-92. PubMed ID: 30296359
[TBL] [Abstract][Full Text] [Related]
15. PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome.
Mueller S; Phillips J; Onar-Thomas A; Romero E; Zheng S; Wiencke JK; McBride SM; Cowdrey C; Prados MD; Weiss WA; Berger MS; Gupta N; Haas-Kogan DA
Neuro Oncol; 2012 Sep; 14(9):1146-52. PubMed ID: 22753230
[TBL] [Abstract][Full Text] [Related]
16. Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.
Jiang Z; Pore N; Cerniglia GJ; Mick R; Georgescu MM; Bernhard EJ; Hahn SM; Gupta AK; Maity A
Cancer Res; 2007 May; 67(9):4467-73. PubMed ID: 17483362
[TBL] [Abstract][Full Text] [Related]
17. Research on miR-126 in glioma targeted regulation of PTEN/PI3K/Akt and MDM2-p53 pathways.
Chen SR; Cai WP; Dai XJ; Guo AS; Chen HP; Lin GS; Lin RS
Eur Rev Med Pharmacol Sci; 2019 Apr; 23(8):3461-3470. PubMed ID: 31081101
[TBL] [Abstract][Full Text] [Related]
18. MicroRNA-146b promotes PI3K/AKT pathway hyperactivation and thyroid cancer progression by targeting PTEN.
Ramírez-Moya J; Wert-Lamas L; Santisteban P
Oncogene; 2018 Jun; 37(25):3369-3383. PubMed ID: 29353884
[TBL] [Abstract][Full Text] [Related]
19. Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions.
Hashemi M; Etemad S; Rezaei S; Ziaolhagh S; Rajabi R; Rahmanian P; Abdi S; Koohpar ZK; Rafiei R; Raei B; Ahmadi F; Salimimoghadam S; Aref AR; Zandieh MA; Entezari M; Taheriazam A; Hushmandi K
Biomed Pharmacother; 2023 Feb; 158():114204. PubMed ID: 36916430
[TBL] [Abstract][Full Text] [Related]
20. Murine models of IDH-wild-type glioblastoma exhibit spatial segregation of tumor initiation and manifestation during evolution.
Li Y; Li B; Li W; Wang Y; Akgül S; Treisman DM; Heist KA; Pierce BR; Hoff B; Ho CY; Ferguson DO; Rehemtulla A; Zheng S; Ross BD; Li JZ; Zhu Y
Nat Commun; 2020 Jul; 11(1):3669. PubMed ID: 32699356
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]