BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 38602289)

  • 1. Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatase Acts as a Tumor Suppressor in Oral Squamous Cell Carcinoma.
    Etemad-Moghadam S; Mohammadpour H; Emami Razavi A; Alaeddini M
    Appl Immunohistochem Mol Morphol; 2024 May-Jun 01; 32(5):249-253. PubMed ID: 38602289
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aberrant expression of PHLPP1 and PHLPP2 correlates with poor prognosis in patients with hypopharyngeal squamous cell carcinoma.
    Zhou J; Yu X; Wang J; Li T; Jin T; Lei D; Pan X
    PLoS One; 2015; 10(3):e0119405. PubMed ID: 25793736
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression and role of oncogenic miRNA-224 in esophageal squamous cell carcinoma.
    He X; Zhang Z; Li M; Li S; Ren L; Zhu H; Xiao B; Shi R
    BMC Cancer; 2015 Aug; 15():575. PubMed ID: 26245343
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP): a new player in cell signaling.
    Warfel NA; Newton AC
    J Biol Chem; 2012 Feb; 287(6):3610-6. PubMed ID: 22144674
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.
    Li X; Stevens PD; Liu J; Yang H; Wang W; Wang C; Zeng Z; Schmidt MD; Yang M; Lee EY; Gao T
    Gastroenterology; 2014 May; 146(5):1301-12.e1-10. PubMed ID: 24530606
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MARCH1 silencing suppresses growth of oral squamous cell carcinoma through regulation of PHLPP2.
    Liu L; Guo B; Han Y; Xu S; Liu S
    Clin Transl Oncol; 2022 Jul; 24(7):1311-1321. PubMed ID: 35122633
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Emerging roles of PHLPP phosphatases in the nervous system.
    Mallick A; Sharma M; Dey CS
    Mol Cell Neurosci; 2022 Dec; 123():103789. PubMed ID: 36343848
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PHLPPing through history: a decade in the life of PHLPP phosphatases.
    Grzechnik AT; Newton AC
    Biochem Soc Trans; 2016 Dec; 44(6):1675-1682. PubMed ID: 27913677
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms.
    Hirano I; Nakamura S; Yokota D; Ono T; Shigeno K; Fujisawa S; Shinjo K; Ohnishi K
    J Biol Chem; 2009 Aug; 284(33):22155-22165. PubMed ID: 19261608
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pleckstrin Homology (PH) Domain Leucine-rich Repeat Protein Phosphatase Controls Cell Polarity by Negatively Regulating the Activity of Atypical Protein Kinase C.
    Xiong X; Li X; Wen YA; Gao T
    J Biol Chem; 2016 Nov; 291(48):25167-25178. PubMed ID: 27760826
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MiR-141-3p is upregulated in esophageal squamous cell carcinoma and targets pleckstrin homology domain leucine-rich repeat protein phosphatase-2, a negative regulator of the PI3K/AKT pathway.
    Ishibashi O; Akagi I; Ogawa Y; Inui T
    Biochem Biophys Res Commun; 2018 Jun; 501(2):507-513. PubMed ID: 29738771
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Suppression of survival signalling pathways by the phosphatase PHLPP.
    O'Neill AK; Niederst MJ; Newton AC
    FEBS J; 2013 Jan; 280(2):572-83. PubMed ID: 22340730
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Turning off AKT: PHLPP as a drug target.
    Newton AC; Trotman LC
    Annu Rev Pharmacol Toxicol; 2014; 54():537-58. PubMed ID: 24392697
    [TBL] [Abstract][Full Text] [Related]  

  • 14. LDOC1 silenced by cigarette exposure and involved in oral neoplastic transformation.
    Lee CH; Pan KL; Tang YC; Tsai MH; Cheng AJ; Shen MY; Cheng YM; Huang TT; Lin P
    Oncotarget; 2015 Sep; 6(28):25188-201. PubMed ID: 26317789
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes.
    Jackson TC; Verrier JD; Drabek T; Janesko-Feldman K; Gillespie DG; Uray T; Dezfulian C; Clark RS; Bayir H; Jackson EK; Kochanek PM
    J Pharmacol Exp Ther; 2013 Nov; 347(2):516-28. PubMed ID: 24023368
    [TBL] [Abstract][Full Text] [Related]  

  • 16. On the PHLPPside: Emerging roles of PHLPP phosphatases in the heart.
    Lemoine KA; Fassas JM; Ohannesian SH; Purcell NH
    Cell Signal; 2021 Oct; 86():110097. PubMed ID: 34320369
    [TBL] [Abstract][Full Text] [Related]  

  • 17. WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1).
    Gangula NR; Maddika S
    J Biol Chem; 2013 Nov; 288(48):34545-54. PubMed ID: 24145035
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Relationship between polycomb-group protein BMI-1 and phosphatases regulating AKT phosphorylation level in endometrial cancer.
    Zaczek A; Jóźwiak P; Ciesielski P; Forma E; Wójcik-Krowiranda K; Cwonda Ł; Bieńkiewicz A; Bryś M; Krześlak A
    J Cell Mol Med; 2020 Jan; 24(2):1300-1310. PubMed ID: 31863623
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mislocalization of the E3 ligase, β-transducin repeat-containing protein 1 (β-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) and Akt.
    Warfel NA; Niederst M; Stevens MW; Brennan PM; Frame MC; Newton AC
    J Biol Chem; 2011 Jun; 286(22):19777-88. PubMed ID: 21454620
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PHLPP Signaling in Immune Cells.
    Lordén G; Lam AJ; Levings MK; Newton AC
    Curr Top Microbiol Immunol; 2022; 436():117-143. PubMed ID: 36243842
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.