BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 38605168)

  • 1. OTUD5 promotes the inflammatory immune response by enhancing MyD88 oligomerization and Myddosome formation.
    Liu Y; Yuan J; Zhang Y; Qin F; Bai X; Sun W; Chen T; Liu F; Zheng Y; Qi X; Zhao W; Liu B; Gao C
    Cell Death Differ; 2024 Jun; 31(6):753-767. PubMed ID: 38605168
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MyD88 oligomer size functions as a physical threshold to trigger IL1R Myddosome signaling.
    Deliz-Aguirre R; Cao F; Gerpott FHU; Auevechanichkul N; Chupanova M; Mun Y; Ziska E; Taylor MJ
    J Cell Biol; 2021 Jul; 220(7):. PubMed ID: 33956941
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling.
    De Nardo D; Balka KR; Cardona Gloria Y; Rao VR; Latz E; Masters SL
    J Biol Chem; 2018 Sep; 293(39):15195-15207. PubMed ID: 30076215
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling.
    Moncrieffe MC; Bollschweiler D; Li B; Penczek PA; Hopkins L; Bryant CE; Klenerman D; Gay NJ
    Structure; 2020 Mar; 28(3):281-289.e3. PubMed ID: 31995744
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Small Molecule Mimetics of α-Helical Domain of IRAK2 Attenuate the Proinflammatory Effects of IL-33 in Asthma-like Mouse Models.
    Li J; Saruta K; Dumouchel JP; Magat JM; Thomas JL; Ajami D; Rebek M; Rebek J; Bigby TD
    J Immunol; 2018 Jun; 200(12):4036-4043. PubMed ID: 29728508
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Data-Driven Modeling Identifies TIRAP-Independent MyD88 Activation Complex and Myddosome Assembly Strategy in LPS/TLR4 Signaling.
    Li X; Zhong CQ; Yin Z; Qi H; Xu F; He Q; Shuai J
    Int J Mol Sci; 2020 Apr; 21(9):. PubMed ID: 32357531
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Two human MYD88 variants, S34Y and R98C, interfere with MyD88-IRAK4-myddosome assembly.
    George J; Motshwene PG; Wang H; Kubarenko AV; Rautanen A; Mills TC; Hill AV; Gay NJ; Weber AN
    J Biol Chem; 2011 Jan; 286(2):1341-53. PubMed ID: 20966070
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling.
    Lin SC; Lo YC; Wu H
    Nature; 2010 Jun; 465(7300):885-90. PubMed ID: 20485341
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interleukin-1 Receptor-Associated Kinase (IRAK) Signaling in Kaposi Sarcoma-Associated Herpesvirus-Induced Primary Effusion Lymphoma.
    Seltzer J; Moorad R; Schifano JM; Landis JT; Dittmer DP
    J Virol; 2020 May; 94(10):. PubMed ID: 32161170
    [TBL] [Abstract][Full Text] [Related]  

  • 10. IRAK4 dimerization and trans-autophosphorylation are induced by Myddosome assembly.
    Ferrao R; Zhou H; Shan Y; Liu Q; Li Q; Shaw DE; Li X; Wu H
    Mol Cell; 2014 Sep; 55(6):891-903. PubMed ID: 25201411
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The N-terminal loop of IRAK-4 death domain regulates ordered assembly of the Myddosome signalling scaffold.
    Dossang AC; Motshwene PG; Yang Y; Symmons MF; Bryant CE; Borman S; George J; Weber AN; Gay NJ
    Sci Rep; 2016 Nov; 6():37267. PubMed ID: 27876844
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Examining Myddosome Formation by Luminescence-Based Mammalian Interactome Mapping (LUMIER).
    Wolz OO; Koegl M; Weber ANR
    Methods Mol Biol; 2018; 1714():119-130. PubMed ID: 29177859
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IinQ attenuates systemic inflammatory responses via selectively impairing the Myddosome complex formation upon TLR4 ligation.
    Kang K; Won M; Yuk JM; Park CY; Byun HS; Park KA; Lee SR; Kang YG; Shen HM; Lee IY; Hur GM
    Biochem Pharmacol; 2016 Dec; 121():52-66. PubMed ID: 27664853
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional assessment of the mutational effects of human IRAK4 and MyD88 genes.
    Yamamoto T; Tsutsumi N; Tochio H; Ohnishi H; Kubota K; Kato Z; Shirakawa M; Kondo N
    Mol Immunol; 2014 Mar; 58(1):66-76. PubMed ID: 24316379
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of optineurin as an interleukin-1 receptor-associated kinase 1-binding protein and its role in regulation of MyD88-dependent signaling.
    Tanishima M; Takashima S; Honda A; Yasuda D; Tanikawa T; Ishii S; MaruYama T
    J Biol Chem; 2017 Oct; 292(42):17250-17257. PubMed ID: 28882891
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutational analysis identifies residues crucial for homodimerization of myeloid differentiation factor 88 (MyD88) and for its function in immune cells.
    Loiarro M; Volpe E; Ruggiero V; Gallo G; Furlan R; Maiorino C; Battistini L; Sette C
    J Biol Chem; 2013 Oct; 288(42):30210-30222. PubMed ID: 24019529
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IRAK4 kinase activity is not required for induction of endotoxin tolerance but contributes to TLR2-mediated tolerance.
    Xiong Y; Pennini M; Vogel SN; Medvedev AE
    J Leukoc Biol; 2013 Aug; 94(2):291-300. PubMed ID: 23695305
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Clinical IRAK4 deficiency caused by homozygosity for the novel
    Jia A; James E; Lu HY; Sharma M; Modi BP; Biggs CM; Hildebrand KJ; Chomyn A; Erdle S; Kular H; Turvey SE
    Cold Spring Harb Mol Case Stud; 2020 Jun; 6(3):. PubMed ID: 32532880
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Understanding early TLR signaling through the Myddosome.
    Balka KR; De Nardo D
    J Leukoc Biol; 2019 Feb; 105(2):339-351. PubMed ID: 30256449
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical Isolation of the Myddosome from Murine Macrophages.
    Tan Y; Kagan JC
    Methods Mol Biol; 2018; 1714():79-95. PubMed ID: 29177857
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.