BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 38608634)

  • 1. SuFEx-based chemical diversification for the systematic discovery of CRBN molecular glues.
    Carter TR; Milosevich N; Dada L; Shaum JB; Barry Sharpless K; Kitamura S; Erb MA
    Bioorg Med Chem; 2024 Apr; 104():117699. PubMed ID: 38608634
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cereblon target validation using a covalent inhibitor of neosubstrate recruitment.
    Dann GP; Liu H; Nowak RP; Jones LH
    Methods Enzymol; 2023; 681():155-167. PubMed ID: 36764755
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A platform for the rapid synthesis of molecular glues (Rapid-Glue) under miniaturized conditions for direct biological screening.
    Li J; Li C; Zhang Z; Zhang Z; Wu Z; Liao J; Wang Z; McReynolds M; Xie H; Guo L; Fan Q; Peng J; Tang W
    Eur J Med Chem; 2023 Oct; 258():115567. PubMed ID: 37390512
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting cereblon in hematologic malignancies.
    Fuchs O
    Blood Rev; 2023 Jan; 57():100994. PubMed ID: 35933246
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular glues targeting GSPT1 in cancers: A potent therapy.
    Zhang D; Lin P; Lin J
    Bioorg Chem; 2024 Feb; 143():107000. PubMed ID: 38029571
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Degron Blocking Strategy Towards Improved CRL4
    Bouguenina H; Scarpino A; O'Hanlon JA; Warne J; Wang HZ; Wah Hak LC; Sadok A; McAndrew PC; Stubbs M; Pierrat OA; Hahner T; Cabry MP; Le Bihan YV; Mitsopoulos C; Sialana FJ; Roumeliotis TI; Burke R; van Montfort RLM; Choudhari J; Chopra R; Caldwell JJ; Collins I
    Chembiochem; 2023 Dec; 24(23):e202300351. PubMed ID: 37418539
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Advancing targeted protein degrader discovery by measuring cereblon engagement in cells.
    Zerfas BL; Huerta F; Liu H; Du G; Gray NS; Jones LH; Nowak RP
    Methods Enzymol; 2023; 681():169-188. PubMed ID: 36764756
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of Phenyl-substituted Isoindolinone- and Benzimidazole-type Cereblon Ligands for Targeted Protein Degradation.
    Nie X; Zhao Y; Tang H; Zhang Z; Liao J; Almodovar-Rivera CM; Sundaresan R; Xie H; Guo L; Wang B; Guan H; Xing Y; Tang W
    Chembiochem; 2024 Feb; 25(4):e202300685. PubMed ID: 38116854
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crbn-based molecular Glues: Breakthroughs and perspectives.
    An J; Zhang X
    Bioorg Med Chem; 2024 Apr; 104():117683. PubMed ID: 38552596
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of Substituted Phenyl Dihydrouracil as the Novel Achiral Cereblon Ligands for Targeted Protein Degradation.
    Xie H; Li C; Tang H; Tandon I; Liao J; Roberts BL; Zhao Y; Tang W
    J Med Chem; 2023 Feb; 66(4):2904-2917. PubMed ID: 36749666
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Modular Chemistry Platform for the Development of a Cereblon E3 Ligase-Based Partial PROTAC Library.
    Almodóvar-Rivera CM; Zhang Z; Li J; Xie H; Zhao Y; Guo L; Mannhardt MG; Tang W
    Chembiochem; 2023 Oct; 24(20):e202300482. PubMed ID: 37418320
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of Highly Potent CRBN Ligands and Insight into Their Binding Mode through Molecular Docking and Molecular Dynamics Simulations.
    Yan J; Zheng Z
    ChemMedChem; 2023 Mar; 18(5):e202200573. PubMed ID: 36750890
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library.
    Powell CE; Du G; Che J; He Z; Donovan KA; Yue H; Wang ES; Nowak RP; Zhang T; Fischer ES; Gray NS
    ACS Chem Biol; 2020 Oct; 15(10):2722-2730. PubMed ID: 32865967
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues.
    Yamanaka S; Horiuchi Y; Matsuoka S; Kido K; Nishino K; Maeno M; Shibata N; Kosako H; Sawasaki T
    Nat Commun; 2022 Jan; 13(1):183. PubMed ID: 35013300
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of novel BCR-ABL PROTACs based on the cereblon E3 ligase design, synthesis, and biological evaluation.
    Liu H; Ding X; Liu L; Mi Q; Zhao Q; Shao Y; Ren C; Chen J; Kong Y; Qiu X; Elvassore N; Yang X; Yin Q; Jiang B
    Eur J Med Chem; 2021 Nov; 223():113645. PubMed ID: 34217059
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology.
    Ito T; Yamaguchi Y; Handa H
    Cell Chem Biol; 2021 Jul; 28(7):987-999. PubMed ID: 34033753
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Trends in Neosubstrate Degradation by Cereblon-Based Molecular Glues and the Development of Novel Multiparameter Optimization Scores.
    Szewczyk SM; Verma I; Edwards JT; Weiss DR; Chekler ELP
    J Med Chem; 2024 Jan; 67(2):1327-1335. PubMed ID: 38170610
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs.
    Lindner S; Steinebach C; Kehm H; Mangold M; Gütschow M; Krönke J
    J Vis Exp; 2019 May; (147):. PubMed ID: 31157769
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ligands for cereblon: 2017-2021 patent overview.
    Kazantsev A; Krasavin M
    Expert Opin Ther Pat; 2022 Feb; 32(2):171-190. PubMed ID: 34704527
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery.
    Wang Z; Shaabani S; Gao X; Ng YLD; Sapozhnikova V; Mertins P; Krönke J; Dömling A
    Nat Commun; 2023 Dec; 14(1):8437. PubMed ID: 38114468
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.