BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 38608795)

  • 1. Transcriptomic profiling analysis of the effect of palmitic acid on 3D spheroids of β-like cells derived from induced pluripotent stem cells.
    Morisseau L; Tokito F; Lucas M; Poulain S; Kim SH; Plaisance V; Pawlowski V; Legallais C; Jellali R; Sakai Y; Abderrahmani A; Leclerc E
    Gene; 2024 Jul; 917():148441. PubMed ID: 38608795
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity.
    Oshima M; Pechberty S; Bellini L; Göpel SO; Campana M; Rouch C; Dairou J; Cosentino C; Fantuzzi F; Toivonen S; Marchetti P; Magnan C; Cnop M; Le Stunff H; Scharfmann R
    Diabetologia; 2020 Feb; 63(2):395-409. PubMed ID: 31796987
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analysis of the behavior of 2D monolayers and 3D spheroid human pancreatic beta cells derived from induced pluripotent stem cells in a microfluidic environment.
    Essaouiba A; Jellali R; Shinohara M; Scheidecker B; Legallais C; Sakai Y; Leclerc E
    J Biotechnol; 2021 Mar; 330():45-56. PubMed ID: 33617908
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Palmitate-Induced Insulin Hypersecretion and Later Secretory Decline Associated with Changes in Protein Expression Patterns in Human Pancreatic Islets.
    Groebe K; Cen J; Schvartz D; Sargsyan E; Chowdhury A; Roomp K; Schneider R; Alderborn A; Sanchez JC; Bergsten P
    J Proteome Res; 2018 Nov; 17(11):3824-3836. PubMed ID: 30183308
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fibroblast growth factor 21 protects against lipotoxicity-induced pancreatic β-cell dysfunction via regulation of AMPK signaling and lipid metabolism.
    Xie T; So WY; Li XY; Leung PS
    Clin Sci (Lond); 2019 Oct; 133(19):2029-2044. PubMed ID: 31654570
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity.
    Lytrivi M; Ghaddar K; Lopes M; Rosengren V; Piron A; Yi X; Johansson H; Lehtiö J; Igoillo-Esteve M; Cunha DA; Marselli L; Marchetti P; Ortsäter H; Eizirik DL; Cnop M
    BMC Genomics; 2020 Aug; 21(1):590. PubMed ID: 32847508
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Efficient generation of functional pancreatic β-cells from human induced pluripotent stem cells.
    Yabe SG; Fukuda S; Takeda F; Nashiro K; Shimoda M; Okochi H
    J Diabetes; 2017 Feb; 9(2):168-179. PubMed ID: 27038181
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of early biological changes in palmitate-treated isolated human islets.
    Sargsyan E; Cen J; Roomp K; Schneider R; Bergsten P
    BMC Genomics; 2018 Aug; 19(1):629. PubMed ID: 30134843
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The STING-IRF3 pathway is involved in lipotoxic injury of pancreatic β cells in type 2 diabetes.
    Hu HQ; Qiao JT; Liu FQ; Wang JB; Sha S; He Q; Cui C; Song J; Zang N; Wang LS; Sun Z; Chen L; Hou XG
    Mol Cell Endocrinol; 2020 Dec; 518():110890. PubMed ID: 32781250
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fetuin A promotes lipotoxicity in β cells through the TLR4 signaling pathway and the role of pioglitazone in anti-lipotoxicity.
    Shen X; Yang L; Yan S; Zheng H; Liang L; Cai X; Liao M
    Mol Cell Endocrinol; 2015 Sep; 412():1-11. PubMed ID: 25986658
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A simple, reliable method for high-throughput screening for diabetes drugs using 3D β-cell spheroids.
    Amin J; Ramachandran K; Williams SJ; Lee A; Novikova L; Stehno-Bittel L
    J Pharmacol Toxicol Methods; 2016; 82():83-89. PubMed ID: 27554916
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells.
    Marafie SK; Al-Shawaf EM; Abubaker J; Arefanian H
    Biol Res; 2019 Aug; 52(1):44. PubMed ID: 31426858
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oleic acid protects insulin-secreting INS-1E cells against palmitic acid-induced lipotoxicity along with an amelioration of ER stress.
    Liu X; Zeng X; Chen X; Luo R; Li L; Wang C; Liu J; Cheng J; Lu Y; Chen Y
    Endocrine; 2019 Jun; 64(3):512-524. PubMed ID: 30778898
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of PPARβ/δ protects pancreatic β cells from palmitate-induced apoptosis by upregulating the expression of GLP-1 receptor.
    Yang Y; Tong Y; Gong M; Lu Y; Wang C; Zhou M; Yang Q; Mao T; Tong N
    Cell Signal; 2014 Feb; 26(2):268-78. PubMed ID: 24269940
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In-vitro and in-vivo studies supporting the therapeutic potential of ZP3022 in diabetes.
    Skarbaliene J; Rigbolt KT; Fosgerau K; Billestrup N
    Eur J Pharmacol; 2017 Nov; 815():181-189. PubMed ID: 28928089
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TCF2 attenuates FFA-induced damage in islet β-cells by regulating production of insulin and ROS.
    Quan X; Zhang L; Li Y; Liang C
    Int J Mol Sci; 2014 Jul; 15(8):13317-32. PubMed ID: 25079440
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protection of palmitic acid-mediated lipotoxicity by arachidonic acid via channeling of palmitic acid into triglycerides in C2C12.
    Cheon HG; Cho YS
    J Biomed Sci; 2014 Feb; 21(1):13. PubMed ID: 24521082
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SIRT6 protects against palmitate-induced pancreatic β-cell dysfunction and apoptosis.
    Xiong X; Sun X; Wang Q; Qian X; Zhang Y; Pan X; Dong XC
    J Endocrinol; 2016 Nov; 231(2):159-165. PubMed ID: 27601447
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic β-cells by stearoyl-CoA desaturase and Elovl6.
    Green CD; Olson LK
    Am J Physiol Endocrinol Metab; 2011 Apr; 300(4):E640-9. PubMed ID: 21266672
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression.
    Mattis KK; Krentz NAJ; Metzendorf C; Abaitua F; Spigelman AF; Sun H; Ikle JM; Thaman S; Rottner AK; Bautista A; Mazzaferro E; Perez-Alcantara M; Manning Fox JE; Torres JM; Wesolowska-Andersen A; Yu GZ; Mahajan A; Larsson A; MacDonald PE; Davies B; den Hoed M; Gloyn AL
    Diabetologia; 2023 Apr; 66(4):674-694. PubMed ID: 36633628
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.