BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

80 related articles for article (PubMed ID: 38616962)

  • 1. The discovery of novel imidazo[1,2-
    Song Q; Zhang Q; Fan X; Kayaat F; Lv R; Li J; Wang Y
    Org Biomol Chem; 2024 Jun; ():. PubMed ID: 38869445
    [TBL] [Abstract][Full Text] [Related]  

  • 2. QM/MM simulations of EFGR with afatinib reveal the role of the
    Ma S; Patel H; Peeples CA; Shen J
    bioRxiv; 2024 May; ():. PubMed ID: 38766221
    [TBL] [Abstract][Full Text] [Related]  

  • 3. KRAS G12C Game of Thrones, which direct KRAS inhibitor will claim the iron throne?
    Nagasaka M; Li Y; Sukari A; Ou SI; Al-Hallak MN; Azmi AS
    Cancer Treat Rev; 2020 Mar; 84():101974. PubMed ID: 32014824
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Covalent inhibitor targets KRas
    Li HY; Qi WL; Wang YX; Meng LH
    Genes Dis; 2023 Mar; 10(2):403-414. PubMed ID: 37223497
    [No Abstract]   [Full Text] [Related]  

  • 5. Multiscale calculations reveal new insights into the reaction mechanism between KRAS
    Yan X; Qu C; Li Q; Zhu L; Tong HHY; Liu H; Ouyang Q; Yao X
    Comput Struct Biotechnol J; 2024 Dec; 23():1408-1417. PubMed ID: 38616962
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proof of concept for poor inhibitor binding and efficient formation of covalent adducts of KRAS
    Khrenova MG; Kulakova AM; Nemukhin AV
    Org Biomol Chem; 2020 Apr; 18(16):3069-3081. PubMed ID: 32101243
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of novel quinazoline-based covalent inhibitors of KRAS G12C with various cysteine-targeting warheads as potential anticancer agents.
    Li L; Zhao H; Liao H; Chen J; Liu J; Chen J
    Bioorg Chem; 2021 May; 110():104825. PubMed ID: 33774492
    [TBL] [Abstract][Full Text] [Related]  

  • 8. High-level QM/MM calculations support the concerted mechanism for Michael addition and covalent complex formation in thymidylate synthase.
    Kaiyawet N; Lonsdale R; Rungrotmongkol T; Mulholland AJ; Hannongbua S
    J Chem Theory Comput; 2015 Feb; 11(2):713-22. PubMed ID: 26579604
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oncogenic KRAS G12C: Kinetic and redox characterization of covalent inhibition.
    Huynh MV; Parsonage D; Forshaw TE; Chirasani VR; Hobbs GA; Wu H; Lee J; Furdui CM; Poole LB; Campbell SL
    J Biol Chem; 2022 Aug; 298(8):102186. PubMed ID: 35753348
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacophoric analogs of sotorasib-entrapped KRAS G12C in its inactive GDP-bound conformation: covalent docking and molecular dynamics investigations.
    Oyedele AK; Ogunlana AT; Boyenle ID; Ibrahim NO; Gbadebo IO; Owolabi NA; Ayoola AM; Francis AC; Eyinade OH; Adelusi TI
    Mol Divers; 2023 Aug; 27(4):1795-1807. PubMed ID: 36271195
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis for inhibition of a GH116 β-glucosidase and its missense mutants by GBA2 inhibitors: Crystallographic and quantum chemical study.
    Meelua W; Thinkumrob N; Saparpakorn P; Pengthaisong S; Hannongbua S; Ketudat Cairns JR; Jitonnom J
    Chem Biol Interact; 2023 Oct; 384():110717. PubMed ID: 37726065
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Multiscale QM/MM Simulations Identify the Roles of Asp239 and 1-OH···Nucleophile in Transition State Stabilization in
    Meelua W; Wanjai T; Thinkumrob N; Friedman R; Jitonnom J
    J Chem Inf Model; 2023 Aug; 63(15):4827-4838. PubMed ID: 37503869
    [No Abstract]   [Full Text] [Related]  

  • 13. Assessment of Reversibility for Covalent Cysteine Protease Inhibitors Using Quantum Mechanics/Molecular Mechanics Free Energy Surfaces.
    Dos Santos AM; Oliveira ARS; da Costa CHS; Kenny PW; Montanari CA; Varela JJG; Lameira J
    J Chem Inf Model; 2022 Sep; 62(17):4083-4094. PubMed ID: 36044342
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanistic Insights into Enzyme Catalysis from Explaining Machine-Learned Quantum Mechanical and Molecular Mechanical Minimum Energy Pathways.
    Song Z; Trozzi F; Tian H; Yin C; Tao P
    ACS Phys Chem Au; 2022 Jul; 2(4):316-330. PubMed ID: 35936506
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nitrogen-Centered Nucleophile Catalyzed Thiol-Vinylsulfone Addition, Another Thiol-ene "Click" Reaction.
    Xi W; Wang C; Kloxin CJ; Bowman CN
    ACS Macro Lett; 2012 Jul; 1(7):811-814. PubMed ID: 35607123
    [TBL] [Abstract][Full Text] [Related]  

  • 16.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 17.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 18.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 19.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 4.