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3. Discovery and characterization of bromodomain 2-specific inhibitors of BRDT. Yu Z; Ku AF; Anglin JL; Sharma R; Ucisik MN; Faver JC; Li F; Nyshadham P; Simmons N; Sharma KL; Nagarajan S; Riehle K; Kaur G; Sankaran B; Storl-Desmond M; Palmer SS; Young DW; Kim C; Matzuk MM Proc Natl Acad Sci U S A; 2021 Mar; 118(9):. PubMed ID: 33637650 [TBL] [Abstract][Full Text] [Related]
4. BET Bromodomain Blockade Mitigates Intimal Hyperplasia in Rat Carotid Arteries. Wang B; Zhang M; Takayama T; Shi X; Roenneburg DA; Kent KC; Guo LW EBioMedicine; 2015 Nov; 2(11):1650-61. PubMed ID: 26870791 [TBL] [Abstract][Full Text] [Related]
5. Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer. Yamamoto K; Tateishi K; Kudo Y; Hoshikawa M; Tanaka M; Nakatsuka T; Fujiwara H; Miyabayashi K; Takahashi R; Tanaka Y; Ijichi H; Nakai Y; Isayama H; Morishita Y; Aoki T; Sakamoto Y; Hasegawa K; Kokudo N; Fukayama M; Koike K Oncotarget; 2016 Sep; 7(38):61469-61484. PubMed ID: 27528027 [TBL] [Abstract][Full Text] [Related]
7. Targeting BRD4 proteins suppresses the growth of NSCLC through downregulation of eIF4E expression. Gao Z; Yuan T; Zhou X; Ni P; Sun G; Li P; Cheng Z; Wang X Cancer Biol Ther; 2018 May; 19(5):407-415. PubMed ID: 29333921 [TBL] [Abstract][Full Text] [Related]
8. BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses. Belkina AC; Nikolajczyk BS; Denis GV J Immunol; 2013 Apr; 190(7):3670-8. PubMed ID: 23420887 [TBL] [Abstract][Full Text] [Related]
9. Nord JA; Wynia-Smith SL; Gehant AL; Jones Lipinski RA; Naatz A; Rioja I; Prinjha RK; Corbett JA; Smith BC Front Endocrinol (Lausanne); 2022; 13():923925. PubMed ID: 36176467 [TBL] [Abstract][Full Text] [Related]
10. Chemical biology. A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes. Baud MGJ; Lin-Shiao E; Cardote T; Tallant C; Pschibul A; Chan KH; Zengerle M; Garcia JR; Kwan TT; Ferguson FM; Ciulli A Science; 2014 Oct; 346(6209):638-641. PubMed ID: 25323695 [TBL] [Abstract][Full Text] [Related]
11. Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer. Leal AS; Williams CR; Royce DB; Pioli PA; Sporn MB; Liby KT Cancer Lett; 2017 May; 394():76-87. PubMed ID: 28254412 [TBL] [Abstract][Full Text] [Related]
12. Design and characterization of bivalent BET inhibitors. Tanaka M; Roberts JM; Seo HS; Souza A; Paulk J; Scott TG; DeAngelo SL; Dhe-Paganon S; Bradner JE Nat Chem Biol; 2016 Dec; 12(12):1089-1096. PubMed ID: 27775715 [TBL] [Abstract][Full Text] [Related]
13. Efficacy of BET bromodomain inhibition in Kras-mutant non-small cell lung cancer. Shimamura T; Chen Z; Soucheray M; Carretero J; Kikuchi E; Tchaicha JH; Gao Y; Cheng KA; Cohoon TJ; Qi J; Akbay E; Kimmelman AC; Kung AL; Bradner JE; Wong KK Clin Cancer Res; 2013 Nov; 19(22):6183-92. PubMed ID: 24045185 [TBL] [Abstract][Full Text] [Related]
14. BET inhibitor nanotherapy halts kidney damage and reduces chronic kidney disease progression after ischemia-reperfusion injury. Saiz ML; Lozano-Chamizo L; Florez AB; Marciello M; Diaz-Bulnes P; Corte-Iglesias V; Bernet CR; Rodrigues-Diez RR; Martin-Martin C; Rodriguez-Santamaria M; Fernandez-Vega I; Rodriguez RM; Diaz-Corte C; Suarez-Alvarez B; Filice M; Lopez-Larrea C Biomed Pharmacother; 2024 May; 174():116492. PubMed ID: 38537579 [TBL] [Abstract][Full Text] [Related]
15. Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains. Lambert JP; Picaud S; Fujisawa T; Hou H; Savitsky P; Uusküla-Reimand L; Gupta GD; Abdouni H; Lin ZY; Tucholska M; Knight JDR; Gonzalez-Badillo B; St-Denis N; Newman JA; Stucki M; Pelletier L; Bandeira N; Wilson MD; Filippakopoulos P; Gingras AC Mol Cell; 2019 Feb; 73(3):621-638.e17. PubMed ID: 30554943 [TBL] [Abstract][Full Text] [Related]
16. BET bromodomain-containing epigenetic reader proteins regulate vascular smooth muscle cell proliferation and neointima formation. Dutzmann J; Haertlé M; Daniel JM; Kloss F; Musmann RJ; Kalies K; Knöpp K; Pilowski C; Sirisko M; Sieweke JT; Bauersachs J; Sedding DG; Gegel S Cardiovasc Res; 2021 Feb; 117(3):850-862. PubMed ID: 32353113 [TBL] [Abstract][Full Text] [Related]
17. Targeting Hippo coactivator YAP1 through BET bromodomain inhibition in esophageal adenocarcinoma. Song S; Li Y; Xu Y; Ma L; Pool Pizzi M; Jin J; Scott AW; Huo L; Wang Y; Lee JH; Bhutani MS; Weston B; Shanbhag ND; Johnson RL; Ajani JA Mol Oncol; 2020 Jun; 14(6):1410-1426. PubMed ID: 32175692 [TBL] [Abstract][Full Text] [Related]
18. Bromodomain and extraterminal inhibition blocks tumor progression and promotes differentiation in neuroblastoma. Lee S; Rellinger EJ; Kim KW; Craig BT; Romain CV; Qiao J; Chung DH Surgery; 2015 Sep; 158(3):819-26. PubMed ID: 26067464 [TBL] [Abstract][Full Text] [Related]
19. BET bromodomain inhibitor JQ1 decreases CD30 and CCR4 expression and proliferation of cutaneous T-cell lymphoma cell lines. Kamijo H; Sugaya M; Takahashi N; Oka T; Miyagaki T; Asano Y; Sato S Arch Dermatol Res; 2017 Aug; 309(6):491-497. PubMed ID: 28593508 [TBL] [Abstract][Full Text] [Related]
20. The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs. Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T Oncotarget; 2016 Nov; 7(48):79217-79232. PubMed ID: 27764794 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]