BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 38630184)

  • 1. Identification of small molecule inhibitors against Lin28/let-7 to suppress tumor progression and its alleviation role in LIN28-dependent glucose metabolism.
    Raja R; Sundararaj R; Kandasamy R
    Med Oncol; 2024 Apr; 41(5):118. PubMed ID: 38630184
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of small molecule inhibitors of the Lin28-mediated blockage of pre-let-7g processing.
    Lightfoot HL; Miska EA; Balasubramanian S
    Org Biomol Chem; 2016 Nov; 14(43):10208-10216. PubMed ID: 27731469
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Spirocyclic Chromenopyrazole Inhibitors Disrupting the Interaction between the RNA-Binding Protein LIN28 and Let-7.
    Borgelt L; Huang F; Hohnen L; Qiu X; Goebel GL; Hommen P; Wu P
    Chembiochem; 2023 Sep; 24(17):e202300168. PubMed ID: 37129525
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lin28/let-7/Bcl-xL pathway: the underlying mechanism of drug resistance in Hep3B cells.
    Tian N; Han Z; Li Z; Zhou M; Fan C
    Oncol Rep; 2014 Sep; 32(3):1050-6. PubMed ID: 24970027
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular Dynamics Simulations for Deciphering the Structural Basis of Recognition of Pre-let-7 miRNAs by LIN28.
    Sharma C; Mohanty D
    Biochemistry; 2017 Feb; 56(5):723-735. PubMed ID: 28076679
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chromenopyrazole-Peptide Conjugates as Small-Molecule Based Inhibitors Disrupting the Protein-RNA Interaction of LIN28-let-7.
    Hommen P; Hwang J; Huang F; Borgelt L; Hohnen L; Wu P
    Chembiochem; 2023 Sep; 24(17):e202300376. PubMed ID: 37224100
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small molecules with tetrahydroquinoline-containing Povarov scaffolds as inhibitors disrupting the Protein-RNA interaction of LIN28-let-7.
    Goebel GL; Hohnen L; Borgelt L; Hommen P; Qiu X; Lightfoot H; Wu P
    Eur J Med Chem; 2022 Jan; 228():114014. PubMed ID: 34883291
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28.
    Wang L; Rowe RG; Jaimes A; Yu C; Nam Y; Pearson DS; Zhang J; Xie X; Marion W; Heffron GJ; Daley GQ; Sliz P
    Cell Rep; 2018 Jun; 23(10):3091-3101. PubMed ID: 29874593
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Small-Molecule Inhibitor of Lin28.
    Roos M; Pradère U; Ngondo RP; Behera A; Allegrini S; Civenni G; Zagalak JA; Marchand JR; Menzi M; Towbin H; Scheuermann J; Neri D; Caflisch A; Catapano CV; Ciaudo C; Hall J
    ACS Chem Biol; 2016 Oct; 11(10):2773-2781. PubMed ID: 27548809
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of Novel Lin28 Inhibitors to Suppress Cancer Cell Stemness.
    Radaeva M; Ho CH; Xie N; Zhang S; Lee J; Liu L; Lallous N; Cherkasov A; Dong X
    Cancers (Basel); 2022 Nov; 14(22):. PubMed ID: 36428779
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Trisubstituted Pyrrolinones as Small-Molecule Inhibitors Disrupting the Protein-RNA Interaction of LIN28 and
    Borgelt L; Li F; Hommen P; Lampe P; Hwang J; Goebel GL; Sievers S; Wu P
    ACS Med Chem Lett; 2021 Jun; 12(6):893-898. PubMed ID: 34136077
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lin28a expression protects against streptozotocin-induced β-cell destruction and prevents diabetes in mice.
    Sung Y; Jeong J; Kang RJ; Choi M; Park S; Kwon W; Lee J; Jang S; Park SJ; Kim SH; Yi J; Choi SK; Lee MH; Liu K; Dong Z; Ryoo ZY; Kim MO
    Cell Biochem Funct; 2019 Apr; 37(3):139-147. PubMed ID: 30883865
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of a Small-Molecule Inhibitor of Protein-MicroRNA Interaction Using Binding Assay with a Site-Specifically Labeled Lin28.
    Lim D; Byun WG; Koo JY; Park H; Park SB
    J Am Chem Soc; 2016 Oct; 138(41):13630-13638. PubMed ID: 27668966
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting ornithine decarboxylase reverses the LIN28/Let-7 axis and inhibits glycolytic metabolism in neuroblastoma.
    Lozier AM; Rich ME; Grawe AP; Peck AS; Zhao P; Chang AT; Bond JP; Sholler GS
    Oncotarget; 2015 Jan; 6(1):196-206. PubMed ID: 25415050
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacological inhibition of Lin28 promotes ketogenesis and restores lipid homeostasis in models of non-alcoholic fatty liver disease.
    Lekka E; Kokanovic A; Mosole S; Civenni G; Schmidli S; Laski A; Ghidini A; Iyer P; Berk C; Behera A; Catapano CV; Hall J
    Nat Commun; 2022 Dec; 13(1):7940. PubMed ID: 36572670
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lin28 promotes dental pulp cell proliferation via upregulation of cyclin-dependent proteins and interaction with let-7a/IGF2BP2 pathways.
    Liu Y; Dong N; Miao J; Li C; Wang X; Ruan J
    Biomed Pharmacother; 2019 May; 113():108742. PubMed ID: 30851545
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Persistent TLR4 Activation Promotes Hepatocellular Carcinoma Growth through Positive Feedback Regulation by LIN28A/Let-7g miRNA.
    Chen IT; Cheng AC; Liu YT; Yan C; Cheng YC; Chang CF; Tseng PH
    Int J Mol Sci; 2022 Jul; 23(15):. PubMed ID: 35955552
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Lin28/let-7 axis regulates glucose metabolism.
    Zhu H; Shyh-Chang N; Segrè AV; Shinoda G; Shah SP; Einhorn WS; Takeuchi A; Engreitz JM; Hagan JP; Kharas MG; Urbach A; Thornton JE; Triboulet R; Gregory RI; ; ; Altshuler D; Daley GQ
    Cell; 2011 Sep; 147(1):81-94. PubMed ID: 21962509
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Peroxisome Proliferator-Activated Receptor γ Expression Is Inversely Associated with Macroscopic Vascular Invasion in Human Hepatocellular Carcinoma.
    Hsu HT; Sung MT; Lee CC; Kuo YJ; Chi CW; Lee HC; Hsia CY
    Int J Mol Sci; 2016 Jul; 17(8):. PubMed ID: 27483249
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of small molecule inhibitors of Zcchc11 TUTase activity.
    Lin S; Gregory RI
    RNA Biol; 2015; 12(8):792-800. PubMed ID: 26114892
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.