175 related articles for article (PubMed ID: 38637616)
1. Genetic modifiers of rare variants in monogenic developmental disorder loci.
Kingdom R; Beaumont RN; Wood AR; Weedon MN; Wright CF
Nat Genet; 2024 May; 56(5):861-868. PubMed ID: 38637616
[TBL] [Abstract][Full Text] [Related]
2. Rare genetic variants in genes and loci linked to dominant monogenic developmental disorders cause milder related phenotypes in the general population.
Kingdom R; Tuke M; Wood A; Beaumont RN; Frayling TM; Weedon MN; Wright CF
Am J Hum Genet; 2022 Jul; 109(7):1308-1316. PubMed ID: 35700724
[TBL] [Abstract][Full Text] [Related]
3. Common genetic variants contribute to risk of rare severe neurodevelopmental disorders.
Niemi MEK; Martin HC; Rice DL; Gallone G; Gordon S; Kelemen M; McAloney K; McRae J; Radford EJ; Yu S; Gecz J; Martin NG; Wright CF; Fitzpatrick DR; Firth HV; Hurles ME; Barrett JC
Nature; 2018 Oct; 562(7726):268-271. PubMed ID: 30258228
[TBL] [Abstract][Full Text] [Related]
4. Analysis of common genetic variation and rare CNVs in the Australian Autism Biobank.
Yap CX; Alvares GA; Henders AK; Lin T; Wallace L; Farrelly A; McLaren T; Berry J; Vinkhuyzen AAE; Trzaskowski M; Zeng J; Yang Y; Cleary D; Grove R; Hafekost C; Harun A; Holdsworth H; Jellett R; Khan F; Lawson L; Leslie J; Levis Frenk M; Masi A; Mathew NE; Muniandy M; Nothard M; Visscher PM; Dawson PA; Dissanayake C; Eapen V; Heussler HS; Whitehouse AJO; Wray NR; Gratten J
Mol Autism; 2021 Feb; 12(1):12. PubMed ID: 33568206
[TBL] [Abstract][Full Text] [Related]
5. Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment.
Shadrin AA; Smeland OB; Zayats T; Schork AJ; Frei O; Bettella F; Witoelar A; Li W; Eriksen JA; Krull F; Djurovic S; Faraone SV; Reichborn-Kjennerud T; Thompson WK; Johansson S; Haavik J; Dale AM; Wang Y; Andreassen OA
J Am Acad Child Adolesc Psychiatry; 2018 Feb; 57(2):86-95. PubMed ID: 29413154
[TBL] [Abstract][Full Text] [Related]
6. Polygenic architecture of rare coding variation across 394,783 exomes.
Weiner DJ; Nadig A; Jagadeesh KA; Dey KK; Neale BM; Robinson EB; Karczewski KJ; O'Connor LJ
Nature; 2023 Feb; 614(7948):492-499. PubMed ID: 36755099
[TBL] [Abstract][Full Text] [Related]
7. Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants.
Saarentaus EC; Havulinna AS; Mars N; Ahola-Olli A; Kiiskinen TTJ; Partanen J; Ruotsalainen S; Kurki M; Urpa LM; Chen L; Perola M; Salomaa V; Veijola J; Männikkö M; Hall IM; Pietiläinen O; Kaprio J; Ripatti S; Daly M; Palotie A
Mol Psychiatry; 2021 Sep; 26(9):4884-4895. PubMed ID: 33526825
[TBL] [Abstract][Full Text] [Related]
8. Common genetic variants with fetal effects on birth weight are enriched for proximity to genes implicated in rare developmental disorders.
Beaumont RN; Mayne IK; Freathy RM; Wright CF
Hum Mol Genet; 2021 May; 30(11):1057-1066. PubMed ID: 33682876
[TBL] [Abstract][Full Text] [Related]
9. Non-additive (dominance) effects of genetic variants associated with refractive error and myopia.
Pozarickij A; Williams C; Guggenheim JA;
Mol Genet Genomics; 2020 Jul; 295(4):843-853. PubMed ID: 32227305
[TBL] [Abstract][Full Text] [Related]
10. Genome-wide association study of multisite chronic pain in UK Biobank.
Johnston KJA; Adams MJ; Nicholl BI; Ward J; Strawbridge RJ; Ferguson A; McIntosh AM; Bailey MES; Smith DJ
PLoS Genet; 2019 Jun; 15(6):e1008164. PubMed ID: 31194737
[TBL] [Abstract][Full Text] [Related]
11. The Polygenic and Monogenic Basis of Blood Traits and Diseases.
Vuckovic D; Bao EL; Akbari P; Lareau CA; Mousas A; Jiang T; Chen MH; Raffield LM; Tardaguila M; Huffman JE; Ritchie SC; Megy K; Ponstingl H; Penkett CJ; Albers PK; Wigdor EM; Sakaue S; Moscati A; Manansala R; Lo KS; Qian H; Akiyama M; Bartz TM; Ben-Shlomo Y; Beswick A; Bork-Jensen J; Bottinger EP; Brody JA; van Rooij FJA; Chitrala KN; Wilson PWF; Choquet H; Danesh J; Di Angelantonio E; Dimou N; Ding J; Elliott P; Esko T; Evans MK; Felix SB; Floyd JS; Broer L; Grarup N; Guo MH; Guo Q; Greinacher A; Haessler J; Hansen T; Howson JMM; Huang W; Jorgenson E; Kacprowski T; Kähönen M; Kamatani Y; Kanai M; Karthikeyan S; Koskeridis F; Lange LA; Lehtimäki T; Linneberg A; Liu Y; Lyytikäinen LP; Manichaikul A; Matsuda K; Mohlke KL; Mononen N; Murakami Y; Nadkarni GN; Nikus K; Pankratz N; Pedersen O; Preuss M; Psaty BM; Raitakari OT; Rich SS; Rodriguez BAT; Rosen JD; Rotter JI; Schubert P; Spracklen CN; Surendran P; Tang H; Tardif JC; Ghanbari M; Völker U; Völzke H; Watkins NA; Weiss S; ; Cai N; Kundu K; Watt SB; Walter K; Zonderman AB; Cho K; Li Y; Loos RJF; Knight JC; Georges M; Stegle O; Evangelou E; Okada Y; Roberts DJ; Inouye M; Johnson AD; Auer PL; Astle WJ; Reiner AP; Butterworth AS; Ouwehand WH; Lettre G; Sankaran VG; Soranzo N
Cell; 2020 Sep; 182(5):1214-1231.e11. PubMed ID: 32888494
[TBL] [Abstract][Full Text] [Related]
12. Polygenic Scores for Cognitive Abilities and Their Association with Different Aspects of General Intelligence-A Deep Phenotyping Approach.
Genç E; Schlüter C; Fraenz C; Arning L; Metzen D; Nguyen HP; Voelkle MC; Streit F; Güntürkün O; Kumsta R; Ocklenburg S
Mol Neurobiol; 2021 Aug; 58(8):4145-4156. PubMed ID: 33954905
[TBL] [Abstract][Full Text] [Related]
13. Monogenic and Polygenic Contributions to QTc Prolongation in the Population.
Nauffal V; Morrill VN; Jurgens SJ; Choi SH; Hall AW; Weng LC; Halford JL; Austin-Tse C; Haggerty CM; Harris SL; Wong EK; Alonso A; Arking DE; Benjamin EJ; Boerwinkle E; Min YI; Correa A; Fornwalt BK; Heckbert SR; ; Kooperberg C; Lin HJ; J F Loos R; Rice KM; Gupta N; Blackwell TW; Mitchell BD; Morrison AC; Psaty BM; Post WS; Redline S; Rehm HL; Rich SS; Rotter JI; Soliman EZ; Sotoodehnia N; Lunetta KL; Ellinor PT; Lubitz SA;
Circulation; 2022 May; 145(20):1524-1533. PubMed ID: 35389749
[TBL] [Abstract][Full Text] [Related]
14. Association of Genetic Variation With Cirrhosis: A Multi-Trait Genome-Wide Association and Gene-Environment Interaction Study.
Emdin CA; Haas M; Ajmera V; Simon TG; Homburger J; Neben C; Jiang L; Wei WQ; Feng Q; Zhou A; Denny J; Corey K; Loomba R; Kathiresan S; Khera AV
Gastroenterology; 2021 Apr; 160(5):1620-1633.e13. PubMed ID: 33310085
[TBL] [Abstract][Full Text] [Related]
15. Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting.
Wright CF; West B; Tuke M; Jones SE; Patel K; Laver TW; Beaumont RN; Tyrrell J; Wood AR; Frayling TM; Hattersley AT; Weedon MN
Am J Hum Genet; 2019 Feb; 104(2):275-286. PubMed ID: 30665703
[TBL] [Abstract][Full Text] [Related]
16. Gene-based burden scores identify rare variant associations for 28 blood biomarkers.
Aldisi R; Hassanin E; Sivalingam S; Buness A; Klinkhammer H; Mayr A; Fröhlich H; Krawitz P; Maj C
BMC Genom Data; 2023 Sep; 24(1):50. PubMed ID: 37667186
[TBL] [Abstract][Full Text] [Related]
17. A phenome-wide association study of 26 mendelian genes reveals phenotypic expressivity of common and rare variants within the general population.
Tcheandjieu C; Aguirre M; Gustafsson S; Saha P; Potiny P; Haendel M; Ingelsson E; Rivas MA; Priest JR
PLoS Genet; 2020 Nov; 16(11):e1008802. PubMed ID: 33226994
[TBL] [Abstract][Full Text] [Related]
18. Monogenic and Polygenic Contributions to Atrial Fibrillation Risk: Results From a National Biobank.
Choi SH; Jurgens SJ; Weng LC; Pirruccello JP; Roselli C; Chaffin M; Lee CJ; Hall AW; Khera AV; Lunetta KL; Lubitz SA; Ellinor PT
Circ Res; 2020 Jan; 126(2):200-209. PubMed ID: 31691645
[TBL] [Abstract][Full Text] [Related]
19. Association of Polygenic Risk for Attention-Deficit/Hyperactivity Disorder With Co-occurring Traits and Disorders.
Du Rietz E; Coleman J; Glanville K; Choi SW; O'Reilly PF; Kuntsi J
Biol Psychiatry Cogn Neurosci Neuroimaging; 2018 Jul; 3(7):635-643. PubMed ID: 30047479
[TBL] [Abstract][Full Text] [Related]
20. Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits.
Zhao B; Luo T; Li T; Li Y; Zhang J; Shan Y; Wang X; Yang L; Zhou F; Zhu Z; ; ; Zhu H
Nat Genet; 2019 Nov; 51(11):1637-1644. PubMed ID: 31676860
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
