BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 38639818)

  • 1. Target-mediated drug disposition model for drugs with N > 2 binding sites that bind to a target with one binding site.
    Gibiansky L; Ng CM; Gibiansky E
    J Pharmacokinet Pharmacodyn; 2024 Apr; ():. PubMed ID: 38639818
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Target-mediated drug disposition model for drugs with two binding sites that bind to a target with one binding site.
    Gibiansky L; Gibiansky E
    J Pharmacokinet Pharmacodyn; 2017 Oct; 44(5):463-475. PubMed ID: 28725976
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Target-mediated drug disposition model for drugs that bind to more than one target.
    Gibiansky L; Gibiansky E
    J Pharmacokinet Pharmacodyn; 2010 Aug; 37(4):323-46. PubMed ID: 20669044
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Approximations of the target-mediated drug disposition model and identifiability of model parameters.
    Gibiansky L; Gibiansky E; Kakkar T; Ma P
    J Pharmacokinet Pharmacodyn; 2008 Oct; 35(5):573-91. PubMed ID: 19005743
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MPBPK-TMDD models for mAbs: alternative models, comparison, and identifiability issues.
    Lavezzi SM; Mezzalana E; Zamuner S; De Nicolao G; Ma P; Simeoni M
    J Pharmacokinet Pharmacodyn; 2018 Dec; 45(6):787-802. PubMed ID: 30415351
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mathematical description of drug-target interactions: application to biologics that bind to targets with two binding sites.
    Gibiansky L; Gibiansky E
    J Pharmacokinet Pharmacodyn; 2018 Feb; 45(1):23-34. PubMed ID: 28918570
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Target-mediated drug disposition with drug-drug interaction, Part I: single drug case in alternative formulations.
    Koch G; Jusko WJ; Schropp J
    J Pharmacokinet Pharmacodyn; 2017 Feb; 44(1):17-26. PubMed ID: 28074395
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Target mediated drug disposition with drug-drug interaction, Part II: competitive and uncompetitive cases.
    Koch G; Jusko WJ; Schropp J
    J Pharmacokinet Pharmacodyn; 2017 Feb; 44(1):27-42. PubMed ID: 28074396
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Validity conditions of approximations for a target-mediated drug disposition model: A novel first-order approximation and its comparison to other approximations.
    Byun JH; Jeon HS; Yun HY; Kim JK
    PLoS Comput Biol; 2024 Apr; 20(4):e1012066. PubMed ID: 38656966
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dose correction for the Michaelis-Menten approximation of the target-mediated drug disposition model.
    Yan X; Krzyzanski W
    J Pharmacokinet Pharmacodyn; 2012 Apr; 39(2):141-6. PubMed ID: 22215144
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Target-mediated exposure enhancement: a previously unexplored limit of TMDD.
    Glassman PM; Muzykantov VR
    J Pharmacokinet Pharmacodyn; 2020 Oct; 47(5):411-420. PubMed ID: 32488574
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dose Correction for a Michaelis-Menten Approximation of a Target-Mediated Drug Disposition Model with a Multiple Intravenous Dosing Regimens.
    Yan X; Ruixo JJP; Krzyzanski W
    AAPS J; 2020 Jan; 22(2):30. PubMed ID: 31950308
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Priori Identifiability of Target-Mediated Drug Disposition Models and Approximations.
    Eudy RJ; Riggs MM; Gastonguay MR
    AAPS J; 2015 Sep; 17(5):1280-4. PubMed ID: 26077506
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selection between Michaelis-Menten and target-mediated drug disposition pharmacokinetic models.
    Yan X; Mager DE; Krzyzanski W
    J Pharmacokinet Pharmacodyn; 2010 Feb; 37(1):25-47. PubMed ID: 20012173
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Incorporating target-mediated drug disposition in a minimal physiologically-based pharmacokinetic model for monoclonal antibodies.
    Cao Y; Jusko WJ
    J Pharmacokinet Pharmacodyn; 2014 Aug; 41(4):375-87. PubMed ID: 25077917
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Infliximab Efficacy May Be Linked to Full TNF-α Blockade in Peripheral Compartment-A Double Central-Peripheral Target-Mediated Drug Disposition (TMDD) Model.
    Ternant D; Le Tilly O; Picon L; Moussata D; Passot C; Bejan-Angoulvant T; Desvignes C; Mulleman D; Goupille P; Paintaud G
    Pharmaceutics; 2021 Nov; 13(11):. PubMed ID: 34834236
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Target-mediated drug disposition model: relationships with indirect response models and application to population PK-PD analysis.
    Gibiansky L; Gibiansky E
    J Pharmacokinet Pharmacodyn; 2009 Aug; 36(4):341-51. PubMed ID: 19578985
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Target-Mediated Drug Disposition Population Pharmacokinetics Model of Alirocumab in Healthy Volunteers and Patients: Pooled Analysis of Randomized Phase I/II/III Studies.
    Djebli N; Martinez JM; Lohan L; Khier S; Brunet A; Hurbin F; Fabre D
    Clin Pharmacokinet; 2017 Oct; 56(10):1155-1171. PubMed ID: 28063030
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tumor necrosis factor-mediated disposition of infliximab in ulcerative colitis patients.
    Berends SE; van Steeg TJ; Ahsman MJ; Singh S; Brandse JF; D'Haens GRAM; Mathôt RAA
    J Pharmacokinet Pharmacodyn; 2019 Dec; 46(6):543-551. PubMed ID: 31489538
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dynamics of target-mediated drug disposition.
    Peletier LA; Gabrielsson J
    Eur J Pharm Sci; 2009 Dec; 38(5):445-64. PubMed ID: 19786099
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.