129 related articles for article (PubMed ID: 38640594)
1. Crystal structure of NRAS Q61K with a ligand-induced pocket near switch II.
Gebregiworgis T; Chan JY; Kuntz DA; Privé GG; Marshall CB; Ikura M
Eur J Cell Biol; 2024 Jun; 103(2):151414. PubMed ID: 38640594
[TBL] [Abstract][Full Text] [Related]
2. Blockade of mutant RAS oncogenic signaling with a special emphasis on KRAS.
Roskoski R
Pharmacol Res; 2021 Oct; 172():105806. PubMed ID: 34450320
[TBL] [Abstract][Full Text] [Related]
3. SP174 Antibody Lacks Specificity for NRAS Q61R and Cross-Reacts With HRAS and KRAS Q61R Mutant Proteins in Malignant Melanoma.
Felisiak-Goląbek A; Inaguma S; Kowalik A; Wasąg B; Wang ZF; Zięba S; Pięciak L; Ryś J; Kopczynski J; Sarlomo-Rikala M; Góźdź S; Lasota J; Miettinen M
Appl Immunohistochem Mol Morphol; 2018 Jan; 26(1):40-45. PubMed ID: 29206715
[TBL] [Abstract][Full Text] [Related]
4. Isomer-sourced structure iteration methods for
Hu Z; Martí J
Comput Struct Biotechnol J; 2024 Dec; 23():2418-2428. PubMed ID: 38882681
[TBL] [Abstract][Full Text] [Related]
5. Mechanisms of isoform-specific residue influence on GTP-bound HRas, KRas, and NRas.
Volmar AY; Guterres H; Zhou H; Reid D; Pavlopoulos S; Makowski L; Mattos C
Biophys J; 2022 Oct; 121(19):3616-3629. PubMed ID: 35794829
[TBL] [Abstract][Full Text] [Related]
6. Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D.
Johnson CW; Lin YJ; Reid D; Parker J; Pavlopoulos S; Dischinger P; Graveel C; Aguirre AJ; Steensma M; Haigis KM; Mattos C
Cell Rep; 2019 Aug; 28(6):1538-1550.e7. PubMed ID: 31390567
[TBL] [Abstract][Full Text] [Related]
7. High-throughput mutation profiling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/MEK signaling cascade.
Kiessling MK; Oberholzer PA; Mondal C; Karpova MB; Zipser MC; Lin WM; Girardi M; Macconaill LE; Kehoe SM; Hatton C; French LE; Garraway LA; Polier G; Süss D; Klemke CD; Krammer PH; Gülow K; Dummer R
Blood; 2011 Feb; 117(8):2433-40. PubMed ID: 21209378
[TBL] [Abstract][Full Text] [Related]
8. Silent mutations reveal therapeutic vulnerability in RAS Q61 cancers.
Kobayashi Y; Chhoeu C; Li J; Price KS; Kiedrowski LA; Hutchins JL; Hardin AI; Wei Z; Hong F; Bahcall M; Gokhale PC; Jänne PA
Nature; 2022 Mar; 603(7900):335-342. PubMed ID: 35236983
[TBL] [Abstract][Full Text] [Related]
9. Drugging all RAS isoforms with one pocket.
Kessler D; Bergner A; Böttcher J; Fischer G; Döbel S; Hinkel M; Müllauer B; Weiss-Puxbaum A; McConnell DB
Future Med Chem; 2020 Nov; 12(21):1911-1923. PubMed ID: 32779487
[TBL] [Abstract][Full Text] [Related]
10. Small molecular inhibitors for KRAS-mutant cancers.
Wu X; Song W; Cheng C; Liu Z; Li X; Cui Y; Gao Y; Li D
Front Immunol; 2023; 14():1223433. PubMed ID: 37662925
[TBL] [Abstract][Full Text] [Related]
11. Drugging an undruggable pocket on KRAS.
Kessler D; Gmachl M; Mantoulidis A; Martin LJ; Zoephel A; Mayer M; Gollner A; Covini D; Fischer S; Gerstberger T; Gmaschitz T; Goodwin C; Greb P; Häring D; Hela W; Hoffmann J; Karolyi-Oezguer J; Knesl P; Kornigg S; Koegl M; Kousek R; Lamarre L; Moser F; Munico-Martinez S; Peinsipp C; Phan J; Rinnenthal J; Sai J; Salamon C; Scherbantin Y; Schipany K; Schnitzer R; Schrenk A; Sharps B; Siszler G; Sun Q; Waterson A; Wolkerstorfer B; Zeeb M; Pearson M; Fesik SW; McConnell DB
Proc Natl Acad Sci U S A; 2019 Aug; 116(32):15823-15829. PubMed ID: 31332011
[TBL] [Abstract][Full Text] [Related]
12. Strategies for Targeting KRAS: A Challenging Drug Target.
Wadood A; Ajmal A; Rehman AU
Curr Pharm Des; 2022; 28(23):1897-1901. PubMed ID: 35524675
[TBL] [Abstract][Full Text] [Related]
13. SP174, NRAS Q61R Mutant-Specific Antibody, Cross-Reacts With KRAS Q61R Mutant Protein in Colorectal Carcinoma.
Lasota J; Kowalik A; Felisiak-Golabek A; Inaguma S; Wang ZF; Pięciak L; Zięba S; Pęksa R; Kopczynski J; Okoń K; Waloszczyk P; Gozdz S; Biernat W; Miettinen M
Arch Pathol Lab Med; 2017 Apr; 141(4):564-568. PubMed ID: 28353383
[TBL] [Abstract][Full Text] [Related]
14. Exploring switch II pocket conformation of KRAS(G12D) with mutant-selective monobody inhibitors.
Akkapeddi P; Hattori T; Khan I; Glasser E; Koide A; Ketavarapu G; Whaby M; Zuberi M; Teng KW; Lefler J; Maso L; Bang I; Ostrowski MC; O'Bryan JP; Koide S
Proc Natl Acad Sci U S A; 2023 Jul; 120(28):e2302485120. PubMed ID: 37399416
[TBL] [Abstract][Full Text] [Related]
15. Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases determined in parallel.
Killoran RC; Smith MJ
J Biol Chem; 2019 Jun; 294(25):9937-9948. PubMed ID: 31088913
[TBL] [Abstract][Full Text] [Related]
16. Transforming mutations of RAC guanosine triphosphatases in human cancers.
Kawazu M; Ueno T; Kontani K; Ogita Y; Ando M; Fukumura K; Yamato A; Soda M; Takeuchi K; Miki Y; Yamaguchi H; Yasuda T; Naoe T; Yamashita Y; Katada T; Choi YL; Mano H
Proc Natl Acad Sci U S A; 2013 Feb; 110(8):3029-34. PubMed ID: 23382236
[TBL] [Abstract][Full Text] [Related]
17. Calmodulin and IQGAP1 activation of PI3Kα and Akt in KRAS, HRAS and NRAS-driven cancers.
Nussinov R; Zhang M; Tsai CJ; Jang H
Biochim Biophys Acta Mol Basis Dis; 2018 Jun; 1864(6 Pt B):2304-2314. PubMed ID: 29097261
[TBL] [Abstract][Full Text] [Related]
18. NRAS mutant E132K identified in young-onset sporadic colorectal cancer and the canonical mutants G12D and Q61K affect distinct oncogenic phenotypes.
Yu RTD; Garcia RL
Sci Rep; 2020 Jul; 10(1):11028. PubMed ID: 32620824
[TBL] [Abstract][Full Text] [Related]
19. NRAS mutation causes a human autoimmune lymphoproliferative syndrome.
Oliveira JB; Bidère N; Niemela JE; Zheng L; Sakai K; Nix CP; Danner RL; Barb J; Munson PJ; Puck JM; Dale J; Straus SE; Fleisher TA; Lenardo MJ
Proc Natl Acad Sci U S A; 2007 May; 104(21):8953-8. PubMed ID: 17517660
[TBL] [Abstract][Full Text] [Related]
20. A Comparative Analysis of Individual RAS Mutations in Cancer Biology.
Muñoz-Maldonado C; Zimmer Y; Medová M
Front Oncol; 2019; 9():1088. PubMed ID: 31681616
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
