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5. PARG is essential for Polθ-mediated DNA end-joining by removing repressive poly-ADP-ribose marks. Vekariya U; Minakhin L; Chandramouly G; Tyagi M; Kent T; Sullivan-Reed K; Atkins J; Ralph D; Nieborowska-Skorska M; Kukuyan AM; Tang HY; Pomerantz RT; Skorski T Nat Commun; 2024 Jul; 15(1):5822. PubMed ID: 38987289 [TBL] [Abstract][Full Text] [Related]
6. Polymerase theta is a synthetic lethal target for killing Epstein-Barr virus lymphomas. Willman GH; Xu H; Zeigler TM; McIntosh MT; Bhaduri-McIntosh S J Virol; 2024 Jul; 98(7):e0057224. PubMed ID: 38860782 [TBL] [Abstract][Full Text] [Related]
7. Template and primer requirements for DNA Pol θ-mediated end joining. He P; Yang W Proc Natl Acad Sci U S A; 2018 Jul; 115(30):7747-7752. PubMed ID: 29987024 [TBL] [Abstract][Full Text] [Related]
8. Structural Basis for Polθ-Helicase DNA Binding and Microhomology-Mediated End-Joining. Ito F; Li Z; Minakhin L; Khant HA; Pomerantz RT; Chen XS bioRxiv; 2024 Jun; ():. PubMed ID: 38895274 [TBL] [Abstract][Full Text] [Related]
9. Poly(ADP) ribose polymerase promotes DNA polymerase theta-mediated end joining by activation of end resection. Luedeman ME; Stroik S; Feng W; Luthman AJ; Gupta GP; Ramsden DA Nat Commun; 2022 Aug; 13(1):4547. PubMed ID: 35927262 [TBL] [Abstract][Full Text] [Related]
10. Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ. Kent T; Chandramouly G; McDevitt SM; Ozdemir AY; Pomerantz RT Nat Struct Mol Biol; 2015 Mar; 22(3):230-7. PubMed ID: 25643323 [TBL] [Abstract][Full Text] [Related]
11. Targeting Polymerase Theta (POLθ) for Cancer Therapy. Patterson-Fortin J; D'Andrea AD Cancer Treat Res; 2023; 186():285-298. PubMed ID: 37978141 [TBL] [Abstract][Full Text] [Related]
12. Dynamic stem-loop extension by Pol θ and templated insertion during DNA repair. Carvajal-Maldonado D; Li Y; Returan M; Averill AM; Doublié S; Wood RD J Biol Chem; 2024 Jul; 300(7):107461. PubMed ID: 38876299 [TBL] [Abstract][Full Text] [Related]
13. Polθ Inhibition: An Anticancer Therapy for HR-Deficient Tumours. Barszczewska-Pietraszek G; Drzewiecka M; Czarny P; Skorski T; Śliwiński T Int J Mol Sci; 2022 Dec; 24(1):. PubMed ID: 36613762 [TBL] [Abstract][Full Text] [Related]
14. Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway. Newman JA; Cooper CDO; Aitkenhead H; Gileadi O Structure; 2015 Dec; 23(12):2319-2330. PubMed ID: 26636256 [TBL] [Abstract][Full Text] [Related]
15. DNA polymerase theta (Polθ) - an error-prone polymerase necessary for genome stability. Brambati A; Barry RM; Sfeir A Curr Opin Genet Dev; 2020 Feb; 60():119-126. PubMed ID: 32302896 [TBL] [Abstract][Full Text] [Related]
16. Mechanism, cellular functions and cancer roles of polymerase-theta-mediated DNA end joining. Ramsden DA; Carvajal-Garcia J; Gupta GP Nat Rev Mol Cell Biol; 2022 Feb; 23(2):125-140. PubMed ID: 34522048 [TBL] [Abstract][Full Text] [Related]
18. Polθ promotes the repair of 5'-DNA-protein crosslinks by microhomology-mediated end-joining. Chandramouly G; Liao S; Rusanov T; Borisonnik N; Calbert ML; Kent T; Sullivan-Reed K; Vekariya U; Kashkina E; Skorski T; Yan H; Pomerantz RT Cell Rep; 2021 Mar; 34(10):108820. PubMed ID: 33691100 [TBL] [Abstract][Full Text] [Related]
19. Mechanistic basis for microhomology identification and genome scarring by polymerase theta. Carvajal-Garcia J; Cho JE; Carvajal-Garcia P; Feng W; Wood RD; Sekelsky J; Gupta GP; Roberts SA; Ramsden DA Proc Natl Acad Sci U S A; 2020 Apr; 117(15):8476-8485. PubMed ID: 32234782 [TBL] [Abstract][Full Text] [Related]
20. POLθ-mediated end joining is restricted by RAD52 and BRCA2 until the onset of mitosis. Llorens-Agost M; Ensminger M; Le HP; Gawai A; Liu J; Cruz-García A; Bhetawal S; Wood RD; Heyer WD; Löbrich M Nat Cell Biol; 2021 Oct; 23(10):1095-1104. PubMed ID: 34616022 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]