BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 38642795)

  • 1. Nanoparticle-mediated delivery of tetrahydrobiopterin restores endothelial function in diabetic rats.
    Kelly KA; Heaps CL; Wu G; Labhasetwar V; Meininger CJ
    Nitric Oxide; 2024 Apr; 148():13-22. PubMed ID: 38642795
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.
    Alp NJ; Mussa S; Khoo J; Cai S; Guzik T; Jefferson A; Goh N; Rockett KA; Channon KM
    J Clin Invest; 2003 Sep; 112(5):725-35. PubMed ID: 12952921
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Uncoupling of endothelial nitric oxide synthase in cerebral vasculature of Tg2576 mice.
    Santhanam AV; d'Uscio LV; He T; Das P; Younkin SG; Katusic ZS
    J Neurochem; 2015 Sep; 134(6):1129-38. PubMed ID: 26111938
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells.
    Sugiyama T; Levy BD; Michel T
    J Biol Chem; 2009 May; 284(19):12691-700. PubMed ID: 19286667
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice.
    Chuaiphichai S; Crabtree MJ; Mcneill E; Hale AB; Trelfa L; Channon KM; Douglas G
    Br J Pharmacol; 2017 Apr; 174(8):657-671. PubMed ID: 28128438
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase.
    Kuzkaya N; Weissmann N; Harrison DG; Dikalov S
    J Biol Chem; 2003 Jun; 278(25):22546-54. PubMed ID: 12692136
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Augmented BH4 by gene transfer restores nitric oxide synthase function in hyperglycemic human endothelial cells.
    Cai S; Khoo J; Channon KM
    Cardiovasc Res; 2005 Mar; 65(4):823-31. PubMed ID: 15721862
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling.
    Antoniades C; Shirodaria C; Warrick N; Cai S; de Bono J; Lee J; Leeson P; Neubauer S; Ratnatunga C; Pillai R; Refsum H; Channon KM
    Circulation; 2006 Sep; 114(11):1193-201. PubMed ID: 16940192
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.
    Cai S; Khoo J; Mussa S; Alp NJ; Channon KM
    Diabetologia; 2005 Sep; 48(9):1933-40. PubMed ID: 16034613
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance.
    Bailey J; Shaw A; Fischer R; Ryan BJ; Kessler BM; McCullagh J; Wade-Martins R; Channon KM; Crabtree MJ
    Free Radic Biol Med; 2017 Mar; 104():214-225. PubMed ID: 28104455
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
    Chuaiphichai S; McNeill E; Douglas G; Crabtree MJ; Bendall JK; Hale AB; Alp NJ; Channon KM
    Hypertension; 2014 Sep; 64(3):530-40. PubMed ID: 24777984
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways.
    Crabtree MJ; Tatham AL; Hale AB; Alp NJ; Channon KM
    J Biol Chem; 2009 Oct; 284(41):28128-28136. PubMed ID: 19666465
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Systemic and vascular oxidation limits the efficacy of oral tetrahydrobiopterin treatment in patients with coronary artery disease.
    Cunnington C; Van Assche T; Shirodaria C; Kylintireas I; Lindsay AC; Lee JM; Antoniades C; Margaritis M; Lee R; Cerrato R; Crabtree MJ; Francis JM; Sayeed R; Ratnatunga C; Pillai R; Choudhury RP; Neubauer S; Channon KM
    Circulation; 2012 Mar; 125(11):1356-66. PubMed ID: 22315282
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms for the role of tetrahydrobiopterin in endothelial function and vascular disease.
    Schmidt TS; Alp NJ
    Clin Sci (Lond); 2007 Jul; 113(2):47-63. PubMed ID: 17555404
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of BH
    DuBose LE; Ozemek C; Wick T; Richardson V; Hildreth KL; Moreau KL
    Am J Physiol Heart Circ Physiol; 2022 Nov; 323(5):H975-H982. PubMed ID: 36149770
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cell type-specific recycling of tetrahydrobiopterin by dihydrofolate reductase explains differential effects of 7,8-dihydrobiopterin on endothelial nitric oxide synthase uncoupling.
    Schmidt K; Kolesnik B; Gorren AC; Werner ER; Mayer B
    Biochem Pharmacol; 2014 Aug; 90(3):246-53. PubMed ID: 24863258
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Relationships between nitric oxide-mediated endothelial function, eNOS coupling and blood pressure revealed by eNOS-GTP cyclohydrolase 1 double transgenic mice.
    Adlam D; Bendall JK; De Bono JP; Alp NJ; Khoo J; Nicoli T; Yokoyama M; Kawashima S; Channon KM
    Exp Physiol; 2007 Jan; 92(1):119-26. PubMed ID: 17012144
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression.
    Bendall JK; Alp NJ; Warrick N; Cai S; Adlam D; Rockett K; Yokoyama M; Kawashima S; Channon KM
    Circ Res; 2005 Oct; 97(9):864-71. PubMed ID: 16179591
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Altered plasma versus vascular biopterins in human atherosclerosis reveal relationships between endothelial nitric oxide synthase coupling, endothelial function, and inflammation.
    Antoniades C; Shirodaria C; Crabtree M; Rinze R; Alp N; Cunnington C; Diesch J; Tousoulis D; Stefanadis C; Leeson P; Ratnatunga C; Pillai R; Channon KM
    Circulation; 2007 Dec; 116(24):2851-9. PubMed ID: 18040031
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Integrated redox sensor and effector functions for tetrahydrobiopterin- and glutathionylation-dependent endothelial nitric-oxide synthase uncoupling.
    Crabtree MJ; Brixey R; Batchelor H; Hale AB; Channon KM
    J Biol Chem; 2013 Jan; 288(1):561-9. PubMed ID: 23139420
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.