These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 38646883)

  • 21. Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors.
    Brosey CA; Houl JH; Katsonis P; Balapiti-Modarage LPF; Bommagani S; Arvai A; Moiani D; Bacolla A; Link T; Warden LS; Lichtarge O; Jones DE; Ahmed Z; Tainer JA
    Prog Biophys Mol Biol; 2021 Aug; 163():171-186. PubMed ID: 33636189
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Binding Adaptation of GS-441524 Diversifies Macro Domains and Downregulates SARS-CoV-2 de-MARylation Capacity.
    Tsika AC; Gallo A; Fourkiotis NK; Argyriou AI; Sreeramulu S; Löhr F; Rogov VV; Richter C; Linhard V; Gande SL; Altincekic N; Krishnathas R; Elamri I; Schwalbe H; Wollenhaupt J; Weiss MS; Spyroulias GA
    J Mol Biol; 2022 Aug; 434(16):167720. PubMed ID: 35839840
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mutation of highly conserved residues in loop 2 of the coronavirus macrodomain demonstrates that enhanced ADP-ribose binding is detrimental to infection.
    Kerr CM; Pfannenstiel JJ; Alhammad YM; Roy A; O'Connor JJ; Ghimire R; Khattabi R; Shrestha R; McDonald PR; Gao P; Johnson DK; More S; Channappanavar R; Fehr AR
    bioRxiv; 2024 Jan; ():. PubMed ID: 38260573
    [TBL] [Abstract][Full Text] [Related]  

  • 24. On the molecular structure of Remdesivir for the treatment of Covid-19.
    Sheikholeslami SM; Jahanbani A; Shao Z
    Comput Methods Biomech Biomed Engin; 2021 Jul; 24(9):995-1002. PubMed ID: 33356621
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus.
    Gordon CJ; Tchesnokov EP; Feng JY; Porter DP; Götte M
    J Biol Chem; 2020 Apr; 295(15):4773-4779. PubMed ID: 32094225
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses.
    Artese A; Svicher V; Costa G; Salpini R; Di Maio VC; Alkhatib M; Ambrosio FA; Santoro MM; Assaraf YG; Alcaro S; Ceccherini-Silberstein F
    Drug Resist Updat; 2020 Dec; 53():100721. PubMed ID: 33132205
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Boceprevir, Calpain Inhibitors II and XII, and GC-376 Have Broad-Spectrum Antiviral Activity against Coronaviruses.
    Hu Y; Ma C; Szeto T; Hurst B; Tarbet B; Wang J
    ACS Infect Dis; 2021 Mar; 7(3):586-597. PubMed ID: 33645977
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Crystal structure and biochemical activity of the macrodomain from rubella virus p150.
    Stoll GA; Nikolopoulos N; Zhai H; Zhang L; Douse CH; Modis Y
    J Virol; 2024 Feb; 98(2):e0177723. PubMed ID: 38289106
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective.
    Seifert M; Bera SC; van Nies P; Kirchdoerfer RN; Shannon A; Le TT; Meng X; Xia H; Wood JM; Harris LD; Papini FS; Arnold JJ; Almo S; Grove TL; Shi PY; Xiang Y; Canard B; Depken M; Cameron CE; Dulin D
    Elife; 2021 Oct; 10():. PubMed ID: 34617885
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
    de Wit E; Feldmann F; Cronin J; Jordan R; Okumura A; Thomas T; Scott D; Cihlar T; Feldmann H
    Proc Natl Acad Sci U S A; 2020 Mar; 117(12):6771-6776. PubMed ID: 32054787
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Compounds with Therapeutic Potential against Novel Respiratory 2019 Coronavirus.
    Martinez MA
    Antimicrob Agents Chemother; 2020 Apr; 64(5):. PubMed ID: 32152082
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites.
    Shannon A; Le NT; Selisko B; Eydoux C; Alvarez K; Guillemot JC; Decroly E; Peersen O; Ferron F; Canard B
    Antiviral Res; 2020 Jun; 178():104793. PubMed ID: 32283108
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The conserved macrodomains of the non-structural proteins of Chikungunya virus and other pathogenic positive strand RNA viruses function as mono-ADP-ribosylhydrolases.
    Eckei L; Krieg S; Bütepage M; Lehmann A; Gross A; Lippok B; Grimm AR; Kümmerer BM; Rossetti G; Lüscher B; Verheugd P
    Sci Rep; 2017 Feb; 7():41746. PubMed ID: 28150709
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV-2 nsp3.
    Frick DN; Virdi RS; Vuksanovic N; Dahal N; Silvaggi NR
    Biochemistry; 2020 Jul; 59(28):2608-2615. PubMed ID: 32578982
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Macro Domain from Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Is an Efficient ADP-ribose Binding Module: CRYSTAL STRUCTURE AND BIOCHEMICAL STUDIES.
    Cho CC; Lin MH; Chuang CY; Hsu CH
    J Biol Chem; 2016 Mar; 291(10):4894-902. PubMed ID: 26740631
    [TBL] [Abstract][Full Text] [Related]  

  • 36. RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery.
    Zhu W; Chen CZ; Gorshkov K; Xu M; Lo DC; Zheng W
    SLAS Discov; 2020 Dec; 25(10):1141-1151. PubMed ID: 32660307
    [TBL] [Abstract][Full Text] [Related]  

  • 37. ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence.
    McPherson RL; Abraham R; Sreekumar E; Ong SE; Cheng SJ; Baxter VK; Kistemaker HA; Filippov DV; Griffin DE; Leung AK
    Proc Natl Acad Sci U S A; 2017 Feb; 114(7):1666-1671. PubMed ID: 28143925
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Off-Target
    Xu Y; Barauskas O; Kim C; Babusis D; Murakami E; Kornyeyev D; Lee G; Stepan G; Perron M; Bannister R; Schultz BE; Sakowicz R; Porter D; Cihlar T; Feng JY
    Antimicrob Agents Chemother; 2021 Jan; 65(2):. PubMed ID: 33229429
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Conformational plasticity of the VEEV macro domain is important for binding of ADP-ribose.
    Makrynitsa GI; Ntonti D; Marousis KD; Birkou M; Matsoukas MT; Asami S; Bentrop D; Papageorgiou N; Canard B; Coutard B; Spyroulias GA
    J Struct Biol; 2019 Apr; 206(1):119-127. PubMed ID: 30825649
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice.
    Schäfer A; Martinez DR; Won JJ; Meganck RM; Moreira FR; Brown AJ; Gully KL; Zweigart MR; Conrad WS; May SR; Dong S; Kalla R; Chun K; Du Pont V; Babusis D; Tang J; Murakami E; Subramanian R; Barrett KT; Bleier BJ; Bannister R; Feng JY; Bilello JP; Cihlar T; Mackman RL; Montgomery SA; Baric RS; Sheahan TP
    Sci Transl Med; 2022 May; 14(643):eabm3410. PubMed ID: 35315683
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.