BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

85 related articles for article (PubMed ID: 38654040)

  • 21. BMS-986158, a Small Molecule Inhibitor of the Bromodomain and Extraterminal Domain Proteins, in Patients with Selected Advanced Solid Tumors: Results from a Phase 1/2a Trial.
    Hilton J; Cristea M; Postel-Vinay S; Baldini C; Voskoboynik M; Edenfield W; Shapiro GI; Cheng ML; Vuky J; Corr B; Das S; Apfel A; Xu K; Kozicki M; Ünsal-Kaçmaz K; Hammell A; Wang G; Ravindran P; Kollia G; Esposito O; Coker S; Diamond JR
    Cancers (Basel); 2022 Aug; 14(17):. PubMed ID: 36077617
    [TBL] [Abstract][Full Text] [Related]  

  • 22. SynergyFinder 3.0: an interactive analysis and consensus interpretation of multi-drug synergies across multiple samples.
    Ianevski A; Giri AK; Aittokallio T
    Nucleic Acids Res; 2022 Jul; 50(W1):W739-W743. PubMed ID: 35580060
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The novel BET inhibitor UM-002 reduces glioblastoma cell proliferation and invasion.
    Jermakowicz AM; Rybin MJ; Suter RK; Sarkaria JN; Zeier Z; Feng Y; Ayad NG
    Sci Rep; 2021 Dec; 11(1):23370. PubMed ID: 34862404
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences.
    Perez-Riverol Y; Bai J; Bandla C; García-Seisdedos D; Hewapathirana S; Kamatchinathan S; Kundu DJ; Prakash A; Frericks-Zipper A; Eisenacher M; Walzer M; Wang S; Brazma A; Vizcaíno JA
    Nucleic Acids Res; 2022 Jan; 50(D1):D543-D552. PubMed ID: 34723319
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design.
    Gavai AV; Norris D; Delucca G; Tortolani D; Tokarski JS; Dodd D; O'Malley D; Zhao Y; Quesnelle C; Gill P; Vaccaro W; Huynh T; Ahuja V; Han WC; Mussari C; Harikrishnan L; Kamau M; Poss M; Sheriff S; Yan C; Marsilio F; Menard K; Wen ML; Rampulla R; Wu DR; Li J; Zhang H; Li P; Sun D; Yip H; Traeger SC; Zhang Y; Mathur A; Zhang H; Huang C; Yang Z; Ranasinghe A; Everlof G; Raghavan N; Tye CK; Wee S; Hunt JT; Vite G; Westhouse R; Lee FY
    J Med Chem; 2021 Oct; 64(19):14247-14265. PubMed ID: 34543572
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mechanisms of temozolomide resistance in glioblastoma - a comprehensive review.
    Singh N; Miner A; Hennis L; Mittal S
    Cancer Drug Resist; 2021; 4(1):17-43. PubMed ID: 34337348
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Drug resistance and combating drug resistance in cancer.
    Wang X; Zhang H; Chen X
    Cancer Drug Resist; 2019; 2(2):141-160. PubMed ID: 34322663
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The synergy of BET inhibitors with aurora A kinase inhibitors in MYCN-amplified neuroblastoma is heightened with functional TP53.
    Yi JS; Sias-Garcia O; Nasholm N; Hu X; Iniguez AB; Hall MD; Davis M; Guha R; Moreno-Smith M; Barbieri E; Duong K; Koach J; Qi J; Bradner JE; Stegmaier K; Weiss WA; Gustafson WC
    Neoplasia; 2021 Jun; 23(6):624-633. PubMed ID: 34107377
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Achieving clinical success with BET inhibitors as anti-cancer agents.
    Shorstova T; Foulkes WD; Witcher M
    Br J Cancer; 2021 Apr; 124(9):1478-1490. PubMed ID: 33723398
    [TBL] [Abstract][Full Text] [Related]  

  • 30. FGF/FGFR signaling in health and disease.
    Xie Y; Su N; Yang J; Tan Q; Huang S; Jin M; Ni Z; Zhang B; Zhang D; Luo F; Chen H; Sun X; Feng JQ; Qi H; Chen L
    Signal Transduct Target Ther; 2020 Sep; 5(1):181. PubMed ID: 32879300
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Role of exosomes in malignant glioma: microRNAs and proteins in pathogenesis and diagnosis.
    Ghaemmaghami AB; Mahjoubin-Tehran M; Movahedpour A; Morshedi K; Sheida A; Taghavi SP; Mirzaei H; Hamblin MR
    Cell Commun Signal; 2020 Aug; 18(1):120. PubMed ID: 32746854
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Genomic and Phenotypic Characterization of a Broad Panel of Patient-Derived Xenografts Reflects the Diversity of Glioblastoma.
    Vaubel RA; Tian S; Remonde D; Schroeder MA; Mladek AC; Kitange GJ; Caron A; Kollmeyer TM; Grove R; Peng S; Carlson BL; Ma DJ; Sarkar G; Evers L; Decker PA; Yan H; Dhruv HD; Berens ME; Wang Q; Marin BM; Klee EW; Califano A; LaChance DH; Eckel-Passow JE; Verhaak RG; Sulman EP; Burns TC; Meyer FB; O'Neill BP; Tran NL; Giannini C; Jenkins RB; Parney IF; Sarkaria JN
    Clin Cancer Res; 2020 Mar; 26(5):1094-1104. PubMed ID: 31852831
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Toward understanding the origin and evolution of cellular organisms.
    Kanehisa M
    Protein Sci; 2019 Nov; 28(11):1947-1951. PubMed ID: 31441146
    [TBL] [Abstract][Full Text] [Related]  

  • 34. BET Inhibition as a Rational Therapeutic Strategy for Invasive Lobular Breast Cancer.
    Walsh L; Haley KE; Moran B; Mooney B; Tarrant F; Madden SF; Di Grande A; Fan Y; Das S; Rueda OM; Dowling CM; Varešlija D; Chin SF; Linn S; Young LS; Jirström K; Crown JP; Bernards R; Caldas C; Gallagher WM; O'Connor DP; Ní Chonghaile T
    Clin Cancer Res; 2019 Dec; 25(23):7139-7150. PubMed ID: 31409615
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer.
    Suo L; Chang X; Xu N; Ji H
    Front Endocrinol (Lausanne); 2019; 10():370. PubMed ID: 31263453
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Intrinsic Resistance to MEK Inhibition through BET Protein-Mediated Kinome Reprogramming in NF1-Deficient Ovarian Cancer.
    Kurimchak AM; Shelton C; Herrera-Montávez C; Duncan KE; Chernoff J; Duncan JS
    Mol Cancer Res; 2019 Aug; 17(8):1721-1734. PubMed ID: 31043489
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma.
    Chua V; Orloff M; Teh JL; Sugase T; Liao C; Purwin TJ; Lam BQ; Terai M; Ambrosini G; Carvajal RD; Schwartz G; Sato T; Aplin AE
    EMBO Mol Med; 2019 Feb; 11(2):. PubMed ID: 30610113
    [TBL] [Abstract][Full Text] [Related]  

  • 38. TAS-120 Cancer Target Binding: Defining Reactivity and Revealing the First Fibroblast Growth Factor Receptor 1 (FGFR1) Irreversible Structure.
    Kalyukina M; Yosaatmadja Y; Middleditch MJ; Patterson AV; Smaill JB; Squire CJ
    ChemMedChem; 2019 Feb; 14(4):494-500. PubMed ID: 30600916
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Drug and disease signature integration identifies synergistic combinations in glioblastoma.
    Stathias V; Jermakowicz AM; Maloof ME; Forlin M; Walters W; Suter RK; Durante MA; Williams SL; Harbour JW; Volmar CH; Lyons NJ; Wahlestedt C; Graham RM; Ivan ME; Komotar RJ; Sarkaria JN; Subramanian A; Golub TR; Schürer SC; Ayad NG
    Nat Commun; 2018 Dec; 9(1):5315. PubMed ID: 30552330
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Structure, activation and dysregulation of fibroblast growth factor receptor kinases: perspectives for clinical targeting.
    Farrell B; Breeze AL
    Biochem Soc Trans; 2018 Dec; 46(6):1753-1770. PubMed ID: 30545934
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.