BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 38664416)

  • 21. Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
    Lasko LM; Jakob CG; Edalji RP; Qiu W; Montgomery D; Digiammarino EL; Hansen TM; Risi RM; Frey R; Manaves V; Shaw B; Algire M; Hessler P; Lam LT; Uziel T; Faivre E; Ferguson D; Buchanan FG; Martin RL; Torrent M; Chiang GG; Karukurichi K; Langston JW; Weinert BT; Choudhary C; de Vries P; Van Drie JH; McElligott D; Kesicki E; Marmorstein R; Sun C; Cole PA; Rosenberg SH; Michaelides MR; Lai A; Bromberg KD
    Nature; 2017 Oct; 550(7674):128-132. PubMed ID: 28953875
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors.
    Yang Y; Zhang R; Li Z; Mei L; Wan S; Ding H; Chen Z; Xing J; Feng H; Han J; Jiang H; Zheng M; Luo C; Zhou B
    J Med Chem; 2020 Feb; 63(3):1337-1360. PubMed ID: 31910017
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Protein lysine acetyltransferase CBP/p300: A promising target for small molecules in cancer treatment.
    Gou P; Zhang W
    Biomed Pharmacother; 2024 Feb; 171():116130. PubMed ID: 38215693
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Epstein-Barr Virus Nuclear Antigen Leader Protein Coactivates EP300.
    Wang C; Zhou H; Xue Y; Liang J; Narita Y; Gerdt C; Zheng AY; Jiang R; Trudeau S; Peng CW; Gewurz BE; Zhao B
    J Virol; 2018 May; 92(9):. PubMed ID: 29467311
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Targeting Lineage-specific MITF Pathway in Human Melanoma Cell Lines by A-485, the Selective Small-molecule Inhibitor of p300/CBP.
    Wang R; He Y; Robinson V; Yang Z; Hessler P; Lasko LM; Lu X; Bhathena A; Lai A; Uziel T; Lam LT
    Mol Cancer Ther; 2018 Dec; 17(12):2543-2550. PubMed ID: 30266801
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mechanism of action and therapeutic efficacy of Aurora kinase B inhibition in MYC overexpressing medulloblastoma.
    Diaz RJ; Golbourn B; Faria C; Picard D; Shih D; Raynaud D; Leadly M; MacKenzie D; Bryant M; Bebenek M; Smith CA; Taylor MD; Huang A; Rutka JT
    Oncotarget; 2015 Feb; 6(5):3359-74. PubMed ID: 25739120
    [TBL] [Abstract][Full Text] [Related]  

  • 27. PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma.
    Singh AR; Joshi S; Zulcic M; Alcaraz M; Garlich JR; Morales GA; Cho YJ; Bao L; Levy ML; Newbury R; Malicki D; Messer K; Crawford J; Durden DL
    PLoS One; 2016; 11(3):e0150836. PubMed ID: 26938241
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Development of Selective CBP/P300 Benzoxazepine Bromodomain Inhibitors.
    Popp TA; Tallant C; Rogers C; Fedorov O; Brennan PE; Müller S; Knapp S; Bracher F
    J Med Chem; 2016 Oct; 59(19):8889-8912. PubMed ID: 27673482
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Medulloblastoma stem cells.
    Fan X; Eberhart CG
    J Clin Oncol; 2008 Jun; 26(17):2821-7. PubMed ID: 18539960
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A Novel Combination Approach Targeting an Enhanced Protein Synthesis Pathway in MYC-driven (Group 3) Medulloblastoma.
    Chaturvedi NK; Kling MJ; Griggs CN; Kesherwani V; Shukla M; McIntyre EM; Ray S; Liu Y; McGuire TR; Sharp JG; Band H; Joshi SS; Coulter DW
    Mol Cancer Ther; 2020 Jun; 19(6):1351-1362. PubMed ID: 32371591
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Recent Advances in the Development of CBP/p300 Bromodomain Inhibitors.
    Xiong Y; Zhang M; Li Y
    Curr Med Chem; 2020; 27(33):5583-5598. PubMed ID: 31364510
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Oncogenic EP300 can be targeted with inhibitors of aldo-keto reductases.
    Mahmud Z; Asaduzzaman M; Kumar U; Masrour N; Jugov R; Coombes RC; Shousha S; Hu Y; Lam EW; Yagüe E
    Biochem Pharmacol; 2019 May; 163():391-403. PubMed ID: 30862505
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734.
    Spriano F; Gaudio E; Cascione L; Tarantelli C; Melle F; Motta G; Priebe V; Rinaldi A; Golino G; Mensah AA; Aresu L; Zucca E; Pileri S; Witcher M; Brown B; Wahlestedt C; Giles F; Stathis A; Bertoni F
    Blood Adv; 2020 Sep; 4(17):4124-4135. PubMed ID: 32882003
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer.
    Jin L; Garcia J; Chan E; de la Cruz C; Segal E; Merchant M; Kharbanda S; Raisner R; Haverty PM; Modrusan Z; Ly J; Choo E; Kaufman S; Beresini MH; Romero FA; Magnuson S; Gascoigne KE
    Cancer Res; 2017 Oct; 77(20):5564-5575. PubMed ID: 28819026
    [TBL] [Abstract][Full Text] [Related]  

  • 35. BET bromodomain protein inhibition is a therapeutic option for medulloblastoma.
    Henssen A; Thor T; Odersky A; Heukamp L; El-Hindy N; Beckers A; Speleman F; Althoff K; Schäfers S; Schramm A; Sure U; Fleischhack G; Eggert A; Schulte JH
    Oncotarget; 2013 Nov; 4(11):2080-95. PubMed ID: 24231268
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Characteristics of anticancer activity of CBP/p300 inhibitors - Features of their classes, intracellular targets and future perspectives of their application in cancer treatment.
    Strachowska M; Robaszkiewicz A
    Pharmacol Ther; 2024 May; 257():108636. PubMed ID: 38521246
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.
    Kasper LH; Fukuyama T; Lerach S; Chang Y; Xu W; Wu S; Boyd KL; Brindle PK
    PLoS One; 2013; 8(12):e82684. PubMed ID: 24340053
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Current development of CBP/p300 inhibitors in the last decade.
    He ZX; Wei BF; Zhang X; Gong YP; Ma LY; Zhao W
    Eur J Med Chem; 2021 Jan; 209():112861. PubMed ID: 33045661
    [TBL] [Abstract][Full Text] [Related]  

  • 39. EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma.
    Durbin AD; Wang T; Wimalasena VK; Zimmerman MW; Li D; Dharia NV; Mariani L; Shendy NAM; Nance S; Patel AG; Shao Y; Mundada M; Maxham L; Park PMC; Sigua LH; Morita K; Conway AS; Robichaud AL; Perez-Atayde AR; Bikowitz MJ; Quinn TR; Wiest O; Easton J; Schönbrunn E; Bulyk ML; Abraham BJ; Stegmaier K; Look AT; Qi J
    Cancer Discov; 2022 Mar; 12(3):730-751. PubMed ID: 34772733
    [TBL] [Abstract][Full Text] [Related]  

  • 40. EP300 as a Molecular Integrator of Fibrotic Transcriptional Programs.
    Rubio K; Molina-Herrera A; Pérez-González A; Hernández-Galdámez HV; Piña-Vázquez C; Araujo-Ramos T; Singh I
    Int J Mol Sci; 2023 Aug; 24(15):. PubMed ID: 37569677
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.