129 related articles for article (PubMed ID: 38703766)
1. Targeting low levels of MIF expression as a potential therapeutic strategy for ALS.
Alfahel L; Gschwendtberger T; Kozareva V; Dumas L; Gibbs R; Kertser A; Baruch K; Zaccai S; Kahn J; Thau-Habermann N; Eggenschwiler R; Sterneckert J; Hermann A; Sundararaman N; Vaibhav V; Van Eyk JE; Rafuse VF; Fraenkel E; Cantz T; Petri S; Israelson A
Cell Rep Med; 2024 May; 5(5):101546. PubMed ID: 38703766
[TBL] [Abstract][Full Text] [Related]
2. AAV2/9-mediated overexpression of MIF inhibits SOD1 misfolding, delays disease onset, and extends survival in mouse models of ALS.
Leyton-Jaimes MF; Kahn J; Israelson A
Proc Natl Acad Sci U S A; 2019 Jul; 116(29):14755-14760. PubMed ID: 31262807
[TBL] [Abstract][Full Text] [Related]
3. Endogenous macrophage migration inhibitory factor reduces the accumulation and toxicity of misfolded SOD1 in a mouse model of ALS.
Leyton-Jaimes MF; Benaim C; Abu-Hamad S; Kahn J; Guetta A; Bucala R; Israelson A
Proc Natl Acad Sci U S A; 2016 Sep; 113(36):10198-203. PubMed ID: 27551074
[TBL] [Abstract][Full Text] [Related]
4. MIF homolog d-dopachrome tautomerase (D-DT/MIF-2) does not inhibit accumulation and toxicity of misfolded SOD1.
Alaskarov A; Barel S; Bakavayev S; Kahn J; Israelson A
Sci Rep; 2022 Jun; 12(1):9570. PubMed ID: 35688953
[TBL] [Abstract][Full Text] [Related]
5. Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons.
Ting HC; Yang HI; Harn HJ; Chiu IM; Su HL; Li X; Chen MF; Ho TJ; Liu CA; Tsai YJ; Chiou TW; Lin SZ; Chang CY
Cells; 2021 Oct; 10(10):. PubMed ID: 34685754
[TBL] [Abstract][Full Text] [Related]
6. MIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS.
Shvil N; Banerjee V; Zoltsman G; Shani T; Kahn J; Abu-Hamad S; Papo N; Engel S; Bernhagen J; Israelson A
Cell Death Dis; 2018 Jan; 9(2):107. PubMed ID: 29371591
[TBL] [Abstract][Full Text] [Related]
7. Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1.
Israelson A; Ditsworth D; Sun S; Song S; Liang J; Hruska-Plochan M; McAlonis-Downes M; Abu-Hamad S; Zoltsman G; Shani T; Maldonado M; Bui A; Navarro M; Zhou H; Marsala M; Kaspar BK; Da Cruz S; Cleveland DW
Neuron; 2015 Apr; 86(1):218-32. PubMed ID: 25801706
[TBL] [Abstract][Full Text] [Related]
8. Pericytes Extend Survival of ALS SOD1 Mice and Induce the Expression of Antioxidant Enzymes in the Murine Model and in IPSCs Derived Neuronal Cells from an ALS Patient.
Coatti GC; Frangini M; Valadares MC; Gomes JP; Lima NO; Cavaçana N; Assoni AF; Pelatti MV; Birbrair A; de Lima ACP; Singer JM; Rocha FMM; Da Silva GL; Mantovani MS; Macedo-Souza LI; Ferrari MFR; Zatz M
Stem Cell Rev Rep; 2017 Oct; 13(5):686-698. PubMed ID: 28710685
[TBL] [Abstract][Full Text] [Related]
9. Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS.
Foust KD; Salazar DL; Likhite S; Ferraiuolo L; Ditsworth D; Ilieva H; Meyer K; Schmelzer L; Braun L; Cleveland DW; Kaspar BK
Mol Ther; 2013 Dec; 21(12):2148-59. PubMed ID: 24008656
[TBL] [Abstract][Full Text] [Related]
10. Induced pluripotent stem cell-derived motor neurons from amyotrophic lateral sclerosis (ALS) patients carrying different superoxide dismutase 1 mutations recapitulate pathological features of ALS.
Liu WC; Liu N; Wang Y; Huang C; Li YF; Wang H; Li XG; Deng M
Chin Med J (Engl); 2021 Oct; 134(20):2457-2464. PubMed ID: 34669638
[TBL] [Abstract][Full Text] [Related]
11. Targeting of monomer/misfolded SOD1 as a therapeutic strategy for amyotrophic lateral sclerosis.
Liu HN; Tjostheim S; Dasilva K; Taylor D; Zhao B; Rakhit R; Brown M; Chakrabartty A; McLaurin J; Robertson J
J Neurosci; 2012 Jun; 32(26):8791-9. PubMed ID: 22745481
[TBL] [Abstract][Full Text] [Related]
12. Wild-type Cu/Zn-superoxide dismutase is misfolded in cerebrospinal fluid of sporadic amyotrophic lateral sclerosis.
Tokuda E; Takei YI; Ohara S; Fujiwara N; Hozumi I; Furukawa Y
Mol Neurodegener; 2019 Nov; 14(1):42. PubMed ID: 31744522
[TBL] [Abstract][Full Text] [Related]
13. Misfolded SOD1 is not a primary component of sporadic ALS.
Da Cruz S; Bui A; Saberi S; Lee SK; Stauffer J; McAlonis-Downes M; Schulte D; Pizzo DP; Parone PA; Cleveland DW; Ravits J
Acta Neuropathol; 2017 Jul; 134(1):97-111. PubMed ID: 28247063
[TBL] [Abstract][Full Text] [Related]
14. Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis.
Bhinge A; Namboori SC; Zhang X; VanDongen AMJ; Stanton LW
Stem Cell Reports; 2017 Apr; 8(4):856-869. PubMed ID: 28366453
[TBL] [Abstract][Full Text] [Related]
15. Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis.
Pokrishevsky E; Grad LI; Yousefi M; Wang J; Mackenzie IR; Cashman NR
PLoS One; 2012; 7(4):e35050. PubMed ID: 22493728
[TBL] [Abstract][Full Text] [Related]
16. Increased surface P2X4 receptors by mutant SOD1 proteins contribute to ALS pathogenesis in SOD1-G93A mice.
Bertin E; Martinez A; Fayoux A; Carvalho K; Carracedo S; Fernagut PO; Koch-Nolte F; Blum D; Bertrand SS; Boué-Grabot E
Cell Mol Life Sci; 2022 Jul; 79(8):431. PubMed ID: 35852606
[TBL] [Abstract][Full Text] [Related]
17. Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.
Hadano S; Mitsui S; Pan L; Otomo A; Kubo M; Sato K; Ono S; Onodera W; Abe K; Chen X; Koike M; Uchiyama Y; Aoki M; Warabi E; Yamamoto M; Ishii T; Yanagawa T; Shang HF; Yoshii F
Hum Mol Genet; 2016 Aug; 25(15):3321-3340. PubMed ID: 27439389
[TBL] [Abstract][Full Text] [Related]
18. The inhibitory effects of MIF on accumulation of canine degenerative myelopathy-associated mutant SOD1 aggregation.
Nomura S; Kobatake Y; Takashima S; Kamishina H; Urushitani M; Nishii N
Res Vet Sci; 2022 Oct; 147():7-11. PubMed ID: 35364344
[TBL] [Abstract][Full Text] [Related]
19. Misfolded SOD1 Accumulation and Mitochondrial Association Contribute to the Selective Vulnerability of Motor Neurons in Familial ALS: Correlation to Human Disease.
Abu-Hamad S; Kahn J; Leyton-Jaimes MF; Rosenblatt J; Israelson A
ACS Chem Neurosci; 2017 Oct; 8(10):2225-2234. PubMed ID: 28715630
[TBL] [Abstract][Full Text] [Related]
20. Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations.
Bursch F; Kalmbach N; Naujock M; Staege S; Eggenschwiler R; Abo-Rady M; Japtok J; Guo W; Hensel N; Reinhardt P; Boeckers TM; Cantz T; Sterneckert J; Van Den Bosch L; Hermann A; Petri S; Wegner F
Hum Mol Genet; 2019 Sep; 28(17):2835-2850. PubMed ID: 31108504
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]