164 related articles for article (PubMed ID: 38706891)
1. Inhibition of esophageal cancer progression through HACE1-TRIP12 interaction and associated RAC1 ubiquitination and degradation.
Hu Y; Zhu Z; Xu Y; Zaman MF; Ge Y; Hu J; Tang X
J Cancer; 2024; 15(10):3114-3127. PubMed ID: 38706891
[No Abstract] [Full Text] [Related]
2. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.
Turgu B; Zhang F; El-Naggar A; Negri GL; Kogler M; Tortola L; Johnson F; Ng T; Li A; Yapp D; Lockwood W; Martinez D; Maris JM; Daugaard M; Penninger JM; Hughes CS; Sorensen PH
Oncogene; 2021 Mar; 40(11):1988-2001. PubMed ID: 33603169
[TBL] [Abstract][Full Text] [Related]
3. HACE1 negatively regulates neuroinflammation through ubiquitylating and degrading Rac1 in Parkinson's disease models.
Zang CX; Wang L; Yang HY; Shang JM; Liu H; Zhang ZH; Ju C; Yuan FY; Li FY; Bao XQ; Zhang D
Acta Pharmacol Sin; 2022 Feb; 43(2):285-294. PubMed ID: 34593974
[TBL] [Abstract][Full Text] [Related]
4. The tumour suppressor HACE1 controls cell migration by regulating Rac1 degradation.
Castillo-Lluva S; Tan CT; Daugaard M; Sorensen PH; Malliri A
Oncogene; 2013 Mar; 32(13):1735-42. PubMed ID: 22614015
[TBL] [Abstract][Full Text] [Related]
5. The E3 ubiquitin-ligase HACE1 catalyzes the ubiquitylation of active Rac1.
Torrino S; Visvikis O; Doye A; Boyer L; Stefani C; Munro P; Bertoglio J; Gacon G; Mettouchi A; Lemichez E
Dev Cell; 2011 Nov; 21(5):959-65. PubMed ID: 22036506
[TBL] [Abstract][Full Text] [Related]
6. Oxygen sensor FIH inhibits HACE1-dependent ubiquitination of Rac1 to enhance metastatic potential in breast cancer cells.
Kim I; Shin SH; Lee JE; Park JW
Oncogene; 2019 May; 38(19):3651-3666. PubMed ID: 30659265
[TBL] [Abstract][Full Text] [Related]
7. Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization.
Singh S; Machida S; Tulsian NK; Choong YK; Ng J; Shankar S; Liu Y; Chandiramani KV; Shi J; Sivaraman J
Adv Sci (Weinh); 2023 Sep; 10(27):e2207672. PubMed ID: 37537642
[TBL] [Abstract][Full Text] [Related]
8. Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.
Andrio E; Lotte R; Hamaoui D; Cherfils J; Doye A; Daugaard M; Sorensen PH; Bost F; Ruimy R; Mettouchi A; Lemichez E
Sci Rep; 2017 Mar; 7():44779. PubMed ID: 28317937
[TBL] [Abstract][Full Text] [Related]
9. Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination.
Acosta MI; Urbach S; Doye A; Ng YW; Boudeau J; Mettouchi A; Debant A; Manser E; Visvikis O; Lemichez E
Sci Rep; 2018 Jan; 8(1):1410. PubMed ID: 29362425
[TBL] [Abstract][Full Text] [Related]
10. The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes.
Turgu B; El-Naggar A; Kogler M; Tortola L; Zhang HF; Hassan M; Lizardo MM; Kung SH; Lam W; Penninger JM; Sorensen PH
EMBO Rep; 2023 Dec; 24(12):e56815. PubMed ID: 37846480
[TBL] [Abstract][Full Text] [Related]
11. Loss of the Tumor Suppressor HACE1 Contributes to Cancer Progression.
Li JC; Chang X; Chen Y; Li XZ; Zhang XL; Yang SM; Hu CJ; Zhang H
Curr Drug Targets; 2019; 20(10):1018-1028. PubMed ID: 30827236
[TBL] [Abstract][Full Text] [Related]
12. HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases.
Kogler M; Tortola L; Negri GL; Leopoldi A; El-Naggar AM; Mereiter S; Gomez-Diaz C; Nitsch R; Tortora D; Kavirayani AM; Gapp BV; Rao S; Uribesalgo I; Hoffmann D; Cikes D; Novatchkova M; Williams DA; Trent JM; Ikeda F; Daugaard M; Hagelkruys A; Sorensen PH; Penninger JM
Cancer Res; 2020 Jul; 80(14):3009-3022. PubMed ID: 32366477
[TBL] [Abstract][Full Text] [Related]
13. Ubiquitylation of active Rac1 by the E3 ubiquitin-ligase HACE1.
Mettouchi A; Lemichez E
Small GTPases; 2012; 3(2):102-6. PubMed ID: 22790197
[TBL] [Abstract][Full Text] [Related]
14. HACE1, an E3 Ubiquitin Protein Ligase, Mitigates Kaposi's Sarcoma-Associated Herpesvirus Infection-Induced Oxidative Stress by Promoting Nrf2 Activity.
Kumar B; Roy A; Asha K; Sharma-Walia N; Ansari MA; Chandran B
J Virol; 2019 May; 93(9):. PubMed ID: 30787155
[TBL] [Abstract][Full Text] [Related]
15. TRIP12 functions as an E3 ubiquitin ligase of APP-BP1.
Park Y; Yoon SK; Yoon JB
Biochem Biophys Res Commun; 2008 Sep; 374(2):294-8. PubMed ID: 18627766
[TBL] [Abstract][Full Text] [Related]
16. Demethylation of the HACE1 gene promoter inhibits the proliferation of human liver cancer cells.
Yu Z; Li Y; Han T; Liu Z
Oncol Lett; 2019 May; 17(5):4361-4368. PubMed ID: 30988809
[TBL] [Abstract][Full Text] [Related]
17. Loss of the E3 ubiquitin ligase HACE1 results in enhanced Rac1 signaling contributing to breast cancer progression.
Goka ET; Lippman ME
Oncogene; 2015 Oct; 34(42):5395-405. PubMed ID: 25659579
[TBL] [Abstract][Full Text] [Related]
18. The E3 ubiquitin ligase thyroid hormone receptor-interacting protein 12 targets pancreas transcription factor 1a for proteasomal degradation.
Hanoun N; Fritsch S; Gayet O; Gigoux V; Cordelier P; Dusetti N; Torrisani J; Dufresne M
J Biol Chem; 2014 Dec; 289(51):35593-604. PubMed ID: 25355311
[TBL] [Abstract][Full Text] [Related]
19. The HECT domain of TRIP12 ubiquitinates substrates of the ubiquitin fusion degradation pathway.
Park Y; Yoon SK; Yoon JB
J Biol Chem; 2009 Jan; 284(3):1540-9. PubMed ID: 19028681
[TBL] [Abstract][Full Text] [Related]
20. HACE1 is a potential tumor suppressor in osteosarcoma.
El-Naggar AM; Clarkson PW; Negri GL; Turgu B; Zhang F; Anglesio MS; Sorensen PH
Cell Death Dis; 2019 Jan; 10(1):21. PubMed ID: 30622235
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]