85 related articles for article (PubMed ID: 3870879)
1. Triazene metabolism. V. Chemical and biological properties of N,N-bis-[(1-aryl-3-methyltriazen-3-yl)-methyl]-methylamines: potential prodrugs for the cytotoxic monomethyltriazenes.
Manning HW; Cameron LM; LaFrance RJ; Vaughan K; Rajaraman R
Anticancer Drug Des; 1985 Oct; 1(1):37-43. PubMed ID: 3870879
[TBL] [Abstract][Full Text] [Related]
2. Triazene metabolism. IV. Derivatives of hydroxymethyltriazenes: potential prodrugs for the active metabolites of the anti-tumour triazene, DTIC.
Cameron LM; LaFrance RJ; Hemens CM; Vaughan K; Rajaraman R; Chubb DC; Goddard PM
Anticancer Drug Des; 1985 Oct; 1(1):27-36. PubMed ID: 3870878
[TBL] [Abstract][Full Text] [Related]
3. Triazene metabolism. VI. 3-Azidomethyl-3-alkyl-1-aryltriazenes, a new class of anti-tumour triazene with potential pro-drug applications.
Vaughan K; Nicholas G; Singer RD; Roy M; Gibson NW
Anticancer Drug Des; 1987 Dec; 2(3):279-87. PubMed ID: 3449091
[TBL] [Abstract][Full Text] [Related]
4. Towards an efficient prodrug of the alkylating metabolite monomethyltriazene: synthesis and stability of N-acylamino acid derivatives of triazenes.
Perry Mde J; Carvalho E; Rosa E; Iley J
Eur J Med Chem; 2009 Mar; 44(3):1049-56. PubMed ID: 18687506
[TBL] [Abstract][Full Text] [Related]
5. Triazene metabolism. II. Transportability and enzyme inhibitory characteristics of metabolites of antitumor dimethyltriazenes.
Godin JR; Llanos G; Vaughan K; Renton KW
Can J Physiol Pharmacol; 1981 Dec; 59(12):1239-44. PubMed ID: 7337878
[TBL] [Abstract][Full Text] [Related]
6. Kinetic investigation of the aqueous stability and antitumor activity of a hydrosoluble diaryltriazene, AVIS, related to the antimetastatic agent DM-COOK.
Lassiani L; Ebert C; Nisi C; Varnavas A; Zorzet S; Sava G; Boccù E
Pharmazie; 1990 Oct; 45(10):743-5. PubMed ID: 2089382
[TBL] [Abstract][Full Text] [Related]
7. Triazene drug metabolites. Part 17: Synthesis and plasma hydrolysis of acyloxymethyl carbamate derivatives of antitumour triazenes.
Carvalho E; Francisco AP; Iley J; Rosa E
Bioorg Med Chem; 2000 Jul; 8(7):1719-25. PubMed ID: 10976519
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and cytotoxic effects of hydroxymethyl-3-pyridyl- and 2-chloro-5-pyridyltriazene derivatives.
Grancharov KC; Koch M; Volm M; Kolar GF
Cancer Lett; 1988 Aug; 41(3):271-9. PubMed ID: 3409206
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of self-immolative glucuronide-based prodrugs of a phenol mustard.
Lougerstay-Madec R; Florent JC; Monneret C; Nemati F; Poupon MF
Anticancer Drug Des; 1998 Dec; 13(8):995-1007. PubMed ID: 10335272
[TBL] [Abstract][Full Text] [Related]
10. In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
Quintieri L; Rosato A; Napoli E; Sola F; Geroni C; Floreani M; Zanovello P
Cancer Res; 2000 Jun; 60(12):3232-8. PubMed ID: 10866316
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and anti-cancer activity of 2,6-disubstituted N-methylpiperidine derivatives and their N-oxides.
Henderson ND; Plumb JA; Robins DJ; Workman P
Anticancer Drug Des; 1996 Sep; 11(6):421-38. PubMed ID: 8836108
[TBL] [Abstract][Full Text] [Related]
12. Self-immolative nitrogen mustard prodrugs for suicide gene therapy.
Niculescu-Duvaz D; Niculescu-Duvaz I; Friedlos F; Martin J; Spooner R; Davies L; Marais R; Springer CJ
J Med Chem; 1998 Dec; 41(26):5297-309. PubMed ID: 9857097
[TBL] [Abstract][Full Text] [Related]
13. Triazene metabolism. III. In vitro cytotoxicity towards M21 cells and in vivo antitumour activity of the proposed metabolites of the antitumour 1-aryl-3,3-dimethyltriazenes.
Kohlsmith DJ; Vaughan K; Luner SJ
Can J Physiol Pharmacol; 1984 Apr; 62(4):396-402. PubMed ID: 6733585
[TBL] [Abstract][Full Text] [Related]
14. Isophosphoramide mustard analogues as prodrugs for anticancer gene-directed enzyme-prodrug therapy (GDEPT).
Misiura K; Szymanowicz D; Kuśnierczyk H; Wietrzyk J; Opolski A
Acta Biochim Pol; 2002; 49(1):169-76. PubMed ID: 12136937
[TBL] [Abstract][Full Text] [Related]
15. Phosphoramidate and phosphate prodrugs of (-)-beta-D-(2R,4R)-dioxolane-thymine: synthesis, anti-HIV activity and stability studies.
Liang Y; Narayanasamy J; Schinazi RF; Chu CK
Bioorg Med Chem; 2006 Apr; 14(7):2178-89. PubMed ID: 16314108
[TBL] [Abstract][Full Text] [Related]
16. Doxorubicin prodrugs with reduced cytotoxicity suited for tumour-specific activation.
Desbène S; Van HD; Michel S; Koch M; Tillequin F; Fournier G; Farjaudon N; Monneret C
Anticancer Drug Des; 1998 Dec; 13(8):955-68. PubMed ID: 10335269
[TBL] [Abstract][Full Text] [Related]
17. Prodrugs of hydroxymethylpentamethylmelamine: a principal active metabolite of the antineoplastic agent hexamethylmelamine.
Ghodrati F; Lavoie EJ
Drug Des Discov; 1994 Feb; 11(2):135-47. PubMed ID: 8075301
[TBL] [Abstract][Full Text] [Related]
18. Triazene drug metabolites: part 15. Synthesis and plasma hydrolysis of anticancer triazenes containing amino acid carriers.
Carvalho E; Iley J; Perry MJ; Rosa E
Pharm Res; 1998 Jun; 15(6):931-5. PubMed ID: 9647361
[TBL] [Abstract][Full Text] [Related]
19. Comparative pharmacology of the novel cyclopropylpyrroloindole-prodrug carzelesin in mice, rats, and humans.
van Tellingen O; Nooijen WJ; Schaaf LJ; van der Valk M; van Asperen J; Henrar RE; Beijnen JH
Cancer Res; 1998 Jun; 58(11):2410-6. PubMed ID: 9622082
[TBL] [Abstract][Full Text] [Related]
20. Suicide gene therapy using E. coli beta-galactosidase.
Farquhar D; Pan BF; Sakurai M; Ghosh A; Mullen CA; Nelson JA
Cancer Chemother Pharmacol; 2002 Jul; 50(1):65-70. PubMed ID: 12111114
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]