These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

290 related articles for article (PubMed ID: 38713502)

  • 1. Some mechanistic underpinnings of molecular adaptations of SARS-COV-2 spike protein by integrating candidate adaptive polymorphisms with protein dynamics.
    Ose NJ; Campitelli P; Modi T; Kazan IC; Kumar S; Ozkan SB
    Elife; 2024 May; 12():. PubMed ID: 38713502
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Some mechanistic underpinnings of molecular adaptations of SARS-COV-2 spike protein by integrating candidate adaptive polymorphisms with protein dynamics.
    Ose NJ; Campitelli P; Modi T; Can Kazan I; Kumar S; Banu Ozkan S
    bioRxiv; 2024 Jan; ():. PubMed ID: 37745560
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ensemble-Based Mutational Profiling and Network Analysis of the SARS-CoV-2 Spike Omicron XBB Lineages for Interactions with the ACE2 Receptor and Antibodies: Cooperation of Binding Hotspots in Mediating Epistatic Couplings Underlies Binding Mechanism and Immune Escape.
    Raisinghani N; Alshahrani M; Gupta G; Verkhivker G
    Int J Mol Sci; 2024 Apr; 25(8):. PubMed ID: 38673865
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AlphaFold2 Modeling and Molecular Dynamics Simulations of the Conformational Ensembles for the SARS-CoV-2 Spike Omicron JN.1, KP.2 and KP.3 Variants: Mutational Profiling of Binding Energetics Reveals Epistatic Drivers of the ACE2 Affinity and Escape Hotspots of Antibody Resistance.
    Raisinghani N; Alshahrani M; Gupta G; Verkhivker G
    Viruses; 2024 Sep; 16(9):. PubMed ID: 39339934
    [TBL] [Abstract][Full Text] [Related]  

  • 5. V367F Mutation in SARS-CoV-2 Spike RBD Emerging during the Early Transmission Phase Enhances Viral Infectivity through Increased Human ACE2 Receptor Binding Affinity.
    Ou J; Zhou Z; Dai R; Zhang J; Zhao S; Wu X; Lan W; Ren Y; Cui L; Lan Q; Lu L; Seto D; Chodosh J; Wu J; Zhang G; Zhang Q
    J Virol; 2021 Jul; 95(16):e0061721. PubMed ID: 34105996
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics.
    Barton MI; MacGowan SA; Kutuzov MA; Dushek O; Barton GJ; van der Merwe PA
    Elife; 2021 Aug; 10():. PubMed ID: 34435953
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural Modeling of the SARS-CoV-2 Spike/Human ACE2 Complex Interface can Identify High-Affinity Variants Associated with Increased Transmissibility.
    Gan HH; Twaddle A; Marchand B; Gunsalus KC
    J Mol Biol; 2021 Jul; 433(15):167051. PubMed ID: 33992693
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular insights into the binding interactions and energetics of the omicron spike variant with hACE2 and a neutralizing antibody.
    Kumar V; Shefrin S; Sundar D
    J Struct Biol; 2024 Jun; 216(2):108087. PubMed ID: 38494148
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exploring conformational landscapes and binding mechanisms of convergent evolution for the SARS-CoV-2 spike Omicron variant complexes with the ACE2 receptor using AlphaFold2-based structural ensembles and molecular dynamics simulations.
    Raisinghani N; Alshahrani M; Gupta G; Xiao S; Tao P; Verkhivker G
    Phys Chem Chem Phys; 2024 Jun; 26(25):17720-17744. PubMed ID: 38869513
    [TBL] [Abstract][Full Text] [Related]  

  • 10. AlphaFold2 Predictions of Conformational Ensembles and Atomistic Simulations of the SARS-CoV-2 Spike XBB Lineages Reveal Epistatic Couplings between Convergent Mutational Hotspots that Control ACE2 Affinity.
    Raisinghani N; Alshahrani M; Gupta G; Xiao S; Tao P; Verkhivker G
    J Phys Chem B; 2024 May; 128(19):4696-4715. PubMed ID: 38696745
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Comparative Analysis of SARS-CoV-2 Variants of Concern (VOC) Spike Proteins Interacting with hACE2 Enzyme.
    Chen J; Chen L; Quan H; Lee S; Khan KF; Xie Y; Li Q; Valero M; Dai Z; Xie Y
    Int J Mol Sci; 2024 Jul; 25(15):. PubMed ID: 39125601
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Probing Mechanisms of Binding and Allostery in the SARS-CoV-2 Spike Omicron Variant Complexes with the Host Receptor: Revealing Functional Roles of the Binding Hotspots in Mediating Epistatic Effects and Communication with Allosteric Pockets.
    Verkhivker G; Agajanian S; Kassab R; Krishnan K
    Int J Mol Sci; 2022 Sep; 23(19):. PubMed ID: 36232845
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhanced binding of the N501Y-mutated SARS-CoV-2 spike protein to the human ACE2 receptor: insights from molecular dynamics simulations.
    Luan B; Wang H; Huynh T
    FEBS Lett; 2021 May; 595(10):1454-1461. PubMed ID: 33728680
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets.
    Raghuvamsi PV; Tulsian NK; Samsudin F; Qian X; Purushotorman K; Yue G; Kozma MM; Hwa WY; Lescar J; Bond PJ; MacAry PA; Anand GS
    Elife; 2021 Feb; 10():. PubMed ID: 33554856
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular characterization of interactions between the D614G variant of SARS-CoV-2 S-protein and neutralizing antibodies: A computational approach.
    Kwarteng A; Asiedu E; Sylverken AA; Larbi A; Sakyi SA; Asiedu SO
    Infect Genet Evol; 2021 Jul; 91():104815. PubMed ID: 33774178
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Computational modeling of the effect of five mutations on the structure of the ACE2 receptor and their correlation with infectivity and virulence of some emerged variants of SARS-CoV-2 suggests mechanisms of binding affinity dysregulation.
    Rodriguez JA; Gonzalez J; Arboleda-Bustos CE; Mendoza N; Martinez C; Pinzon A
    Chem Biol Interact; 2022 Dec; 368():110244. PubMed ID: 36336003
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution.
    Zahradník J; Marciano S; Shemesh M; Zoler E; Harari D; Chiaravalli J; Meyer B; Rudich Y; Li C; Marton I; Dym O; Elad N; Lewis MG; Andersen H; Gagne M; Seder RA; Douek DC; Schreiber G
    Nat Microbiol; 2021 Sep; 6(9):1188-1198. PubMed ID: 34400835
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Balancing Functional Tradeoffs between Protein Stability and ACE2 Binding in the SARS-CoV-2 Omicron BA.2, BA.2.75 and XBB Lineages: Dynamics-Based Network Models Reveal Epistatic Effects Modulating Compensatory Dynamic and Energetic Changes.
    Verkhivker G; Alshahrani M; Gupta G
    Viruses; 2023 May; 15(5):. PubMed ID: 37243229
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Computer Simulations and Network-Based Profiling of Binding and Allosteric Interactions of SARS-CoV-2 Spike Variant Complexes and the Host Receptor: Dissecting the Mechanistic Effects of the Delta and Omicron Mutations.
    Verkhivker G; Agajanian S; Kassab R; Krishnan K
    Int J Mol Sci; 2022 Apr; 23(8):. PubMed ID: 35457196
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutations on RBD of SARS-CoV-2 Omicron variant result in stronger binding to human ACE2 receptor.
    Lupala CS; Ye Y; Chen H; Su XD; Liu H
    Biochem Biophys Res Commun; 2022 Jan; 590():34-41. PubMed ID: 34968782
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.