BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 38722298)

  • 1. Charcot-Marie-Tooth type 2A in vivo models: Current updates.
    Abati E; Rizzuti M; Anastasia A; Comi GP; Corti S; Rizzo F
    J Cell Mol Med; 2024 May; 28(9):e18293. PubMed ID: 38722298
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitochondrial Dysfunction and Pharmacodynamics of Mitofusin Activation in Murine Charcot-Marie-Tooth Disease Type 2A.
    Franco A; Dang X; Zhang L; Molinoff PB; Dorn GW
    J Pharmacol Exp Ther; 2022 Nov; 383(2):137-148. PubMed ID: 36507849
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A.
    Franco A; Dang X; Walton EK; Ho JN; Zablocka B; Ly C; Miller TM; Baloh RH; Shy ME; Yoo AS; Dorn GW
    Elife; 2020 Oct; 9():. PubMed ID: 33074106
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitochondrial fusion and function in Charcot-Marie-Tooth type 2A patient fibroblasts with mitofusin 2 mutations.
    Amiott EA; Lott P; Soto J; Kang PB; McCaffery JM; DiMauro S; Abel ED; Flanigan KM; Lawson VH; Shaw JM
    Exp Neurol; 2008 May; 211(1):115-27. PubMed ID: 18316077
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MFN2-related neuropathies: Clinical features, molecular pathogenesis and therapeutic perspectives.
    Stuppia G; Rizzo F; Riboldi G; Del Bo R; Nizzardo M; Simone C; Comi GP; Bresolin N; Corti S
    J Neurol Sci; 2015 Sep; 356(1-2):7-18. PubMed ID: 26143526
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy.
    Das R; Maity S; Das P; Kamal IM; Chakrabarti S; Chakrabarti O
    Mitochondrion; 2024 Jan; 74():101825. PubMed ID: 38092249
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A mutation associated with CMT2A neuropathy causes defects in Fzo1 GTP hydrolysis, ubiquitylation, and protein turnover.
    Amiott EA; Cohen MM; Saint-Georges Y; Weissman AM; Shaw JM
    Mol Biol Cell; 2009 Dec; 20(23):5026-35. PubMed ID: 19812251
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MFN2 mutations in Charcot-Marie-Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics.
    Larrea D; Pera M; Gonnelli A; Quintana-Cabrera R; Akman HO; Guardia-Laguarta C; Velasco KR; Area-Gomez E; Dal Bello F; De Stefani D; Horvath R; Shy ME; Schon EA; Giacomello M
    Hum Mol Genet; 2019 Jun; 28(11):1782-1800. PubMed ID: 30649465
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Charcot-Marie-tooth disease type 2A: An update on pathogenesis and therapeutic perspectives.
    Alberti C; Rizzo F; Anastasia A; Comi G; Corti S; Abati E
    Neurobiol Dis; 2024 Apr; 193():106467. PubMed ID: 38452947
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combined RNA interference and gene replacement therapy targeting MFN2 as proof of principle for the treatment of Charcot-Marie-Tooth type 2A.
    Rizzo F; Bono S; Ruepp MD; Salani S; Ottoboni L; Abati E; Melzi V; Cordiglieri C; Pagliarani S; De Gioia R; Anastasia A; Taiana M; Garbellini M; Lodato S; Kunderfranco P; Cazzato D; Cartelli D; Lonati C; Bresolin N; Comi G; Nizzardo M; Corti S
    Cell Mol Life Sci; 2023 Nov; 80(12):373. PubMed ID: 38007410
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model.
    Zhou Y; Carmona S; Muhammad AKMG; Bell S; Landeros J; Vazquez M; Ho R; Franco A; Lu B; Dorn GW; Wang S; Lutz CM; Baloh RH
    J Clin Invest; 2019 Mar; 129(4):1756-1771. PubMed ID: 30882371
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased mitochondrial fusion in a autosomal recessive CMT2A family with mitochondrial GTPase mitofusin 2 mutations.
    Codron P; Chevrollier A; Kane MS; Echaniz-Laguna A; Latour P; Reynier P; Bonneau D; Verny C; Procaccio V; Lenaers G; Cassereau J
    J Peripher Nerv Syst; 2016 Dec; 21(4):365-369. PubMed ID: 27706887
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Natural history of Charcot-Marie-Tooth disease type 2A: a large international multicentre study.
    Pipis M; Feely SME; Polke JM; Skorupinska M; Perez L; Shy RR; Laura M; Morrow JM; Moroni I; Pisciotta C; Taroni F; Vujovic D; Lloyd TE; Acsadi G; Yum SW; Lewis RA; Finkel RS; Herrmann DN; Day JW; Li J; Saporta M; Sadjadi R; Walk D; Burns J; Muntoni F; Ramchandren S; Horvath R; Johnson NE; Züchner S; Pareyson D; Scherer SS; Rossor AM; Shy ME; Reilly MM;
    Brain; 2020 Dec; 143(12):3589-3602. PubMed ID: 33415332
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aberrant Mitochondrial Dynamics and Exacerbated Response to Neuroinflammation in a Novel Mouse Model of CMT2A.
    Stavropoulos F; Sargiannidou I; Potamiti L; Kagiava A; Panayiotidis MI; Bae JH; Yeom SC; Lee JY; Kleopa KA
    Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34769001
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MITOL-mediated DRP1 ubiquitylation and degradation promotes mitochondrial hyperfusion in a CMT2A-linked MFN2 mutant.
    Das R; Kamal IM; Das S; Chakrabarti S; Chakrabarti O
    J Cell Sci; 2022 Jan; 135(2):. PubMed ID: 34870686
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of mitofusin 2 mutations in the physiopathology of Charcot-Marie-Tooth disease type 2A.
    Cartoni R; Martinou JC
    Exp Neurol; 2009 Aug; 218(2):268-73. PubMed ID: 19427854
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A human mitofusin 2 mutation can cause mitophagic cardiomyopathy.
    Franco A; Li J; Kelly DP; Hershberger RE; Marian AJ; Lewis RM; Song M; Dang X; Schmidt AD; Mathyer ME; Edwards JR; Strong CG; Dorn GW
    Elife; 2023 Nov; 12():. PubMed ID: 37910431
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitofusin 1 overexpression rescues the abnormal mitochondrial dynamics caused by the Mitofusin 2 K357T mutation in vitro.
    Stavropoulos F; Georgiou E; Schiza N; Bell S; Baloh RH; Kleopa KA; Sargiannidou I
    J Peripher Nerv Syst; 2023 Sep; 28(3):329-340. PubMed ID: 37220142
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Charcot-Marie Tooth Disease Mutation R94Q in MFN2 Decreases ATP Production but Increases Mitochondrial Respiration under Conditions of Mild Oxidative Stress.
    Wolf C; Zimmermann R; Thaher O; Bueno D; Wüllner V; Schäfer MKE; Albrecht P; Methner A
    Cells; 2019 Oct; 8(10):. PubMed ID: 31640251
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations.
    Baloh RH; Schmidt RE; Pestronk A; Milbrandt J
    J Neurosci; 2007 Jan; 27(2):422-30. PubMed ID: 17215403
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.