122 related articles for article (PubMed ID: 38723915)
1. The use of bispyridinium non-oxime analogues for the restoration of nerve agent impaired neuromuscular transmission in rat hemidiaphragms - Structure optimization.
Amend N; Timperley CM; Bird M; Green AC; Worek F; Seeger T
Toxicol Lett; 2024 Jun; 397():42-47. PubMed ID: 38723915
[TBL] [Abstract][Full Text] [Related]
2. Restoration of nerve agent impaired neuromuscular transmission in rat diaphragm by bispyridinium non-oximes - Structure-activity relationships.
Amend N; Timperley CM; Bird M; Green AC; Worek F; Seeger T
Toxicology; 2024 Mar; 503():153741. PubMed ID: 38311098
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological evaluation of novel MB327 analogs as resensitizers for desensitized nicotinic acetylcholine receptors after intoxication with nerve agents.
Bernauer T; Nitsche V; Kaiser J; Gertzen CGW; Höfner G; Niessen KV; Seeger T; Steinritz D; Worek F; Gohlke H; Wanner KT; Paintner FF
Toxicol Lett; 2024 Jun; 397():151-162. PubMed ID: 38759939
[TBL] [Abstract][Full Text] [Related]
4. Affinities of bispyridinium non-oxime compounds to [(3)H]epibatidine binding sites of Torpedo californica nicotinic acetylcholine receptors depend on linker length.
Niessen KV; Seeger T; Tattersall JE; Timperley CM; Bird M; Green C; Thiermann H; Worek F
Chem Biol Interact; 2013 Dec; 206(3):545-54. PubMed ID: 24157926
[TBL] [Abstract][Full Text] [Related]
5. In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2- and 3-regioisomers.
Niessen KV; Seeger T; Rappenglück S; Wein T; Höfner G; Wanner KT; Thiermann H; Worek F
Toxicol Lett; 2018 Sep; 293():190-197. PubMed ID: 29024789
[TBL] [Abstract][Full Text] [Related]
6. Restoration of soman-blocked neuromuscular transmission in human and rat muscle by the bispyridinium non-oxime MB327 in vitro.
Seeger T; Eichhorn M; Lindner M; Niessen KV; Tattersall JE; Timperley CM; Bird M; Green AC; Thiermann H; Worek F
Toxicology; 2012 Apr; 294(2-3):80-4. PubMed ID: 22349640
[TBL] [Abstract][Full Text] [Related]
7. Counteracting desensitization of human α7-nicotinic acetylcholine receptors with bispyridinium compounds as an approach against organophosphorus poisoning.
Scheffel C; Niessen KV; Rappenglück S; Wanner KT; Thiermann H; Worek F; Seeger T
Toxicol Lett; 2018 Sep; 293():149-156. PubMed ID: 29248576
[TBL] [Abstract][Full Text] [Related]
8. New Resensitizers for the Nicotinic Acetylcholine Receptor by Ligand-Based Pharmacophore Modeling.
Wein T; Wanner KT; Rappenglück S; Sichler S; Niessen KV; Seeger T; Worek F; Thiermann H
Curr Comput Aided Drug Des; 2019; 15(1):104-109. PubMed ID: 29968541
[TBL] [Abstract][Full Text] [Related]
9. Evaluation of the Influence of Three Newly Developed Bispyridinium Anti-nicotinic Compounds (MB408, MB442, MB444) on the Efficacy of Antidotal Treatment of Nerve Agent Poisoning in Mice.
Kassa J; Timperley CM; Bird M; Williams RL; Green AC; Tattersall JEH
Basic Clin Pharmacol Toxicol; 2018 Apr; 122(4):429-435. PubMed ID: 29117635
[TBL] [Abstract][Full Text] [Related]
10. Analysis of oxime-induced neuromuscular recovery in guinea pig, rat and man following soman poisoning in vitro.
Smith AP; Van der Wiel HJ; Wolthuis OL
Eur J Pharmacol; 1981 Mar; 70(3):371-9. PubMed ID: 6262099
[TBL] [Abstract][Full Text] [Related]
11. Some benefit from non-oximes MB408, MB442 and MB444 in combination with the oximes HI-6 or obidoxime and atropine in antidoting sarin or cyclosarin poisoned mice.
Kassa J; Timperley CM; Bird M; Williams RL; Green AC; Tattersall JEH
Toxicology; 2018 Sep; 408():95-100. PubMed ID: 30005893
[TBL] [Abstract][Full Text] [Related]
12. Functional basis for dose-dependent antagonism of rat and rabbit neuromuscular transmission by the bis-pyridinium oxime MMB4.
Machamer JB; Apland JP; Winner BM; Wolfe SE; Pagarigan KT; Bounader KM; Kasten SA; Adler M; McNutt PM
Arch Toxicol; 2020 Nov; 94(11):3877-3891. PubMed ID: 32691075
[TBL] [Abstract][Full Text] [Related]
13. Interaction of bispyridinium compounds with the orthosteric binding site of human α7 and Torpedo californica nicotinic acetylcholine receptors (nAChRs).
Niessen KV; Tattersall JE; Timperley CM; Bird M; Green C; Seeger T; Thiermann H; Worek F
Toxicol Lett; 2011 Sep; 206(1):100-4. PubMed ID: 21703337
[TBL] [Abstract][Full Text] [Related]
14. Prophylactic potential of memantine against soman poisoning in rats.
Stojiljković MP; Škrbić R; Jokanović M; Bokonjić D; Kilibarda V; Vulović M
Toxicology; 2019 Mar; 416():62-74. PubMed ID: 30682440
[TBL] [Abstract][Full Text] [Related]
15. Searching for putative binding sites of the bispyridinium compound MB327 in the nicotinic acetylcholine receptor.
Wein T; Höfner G; Rappenglück S; Sichler S; Niessen KV; Seeger T; Worek F; Thiermann H; Wanner KT
Toxicol Lett; 2018 Sep; 293():184-189. PubMed ID: 29097222
[TBL] [Abstract][Full Text] [Related]
16. A novel binding site in the nicotinic acetylcholine receptor for MB327 can explain its allosteric modulation relevant for organophosphorus-poisoning treatment.
Kaiser J; Gertzen CGW; Bernauer T; Höfner G; Niessen KV; Seeger T; Paintner FF; Wanner KT; Worek F; Thiermann H; Gohlke H
Toxicol Lett; 2023 Jan; 373():160-171. PubMed ID: 36503818
[TBL] [Abstract][Full Text] [Related]
17. Electrophysiological investigation of the effect of structurally different bispyridinium non-oxime compounds on human α7-nicotinic acetylcholine receptor activity-An in vitro structure-activity analysis.
Scheffel C; Niessen KV; Rappenglück S; Wanner KT; Thiermann H; Worek F; Seeger T
Toxicol Lett; 2018 Sep; 293():157-166. PubMed ID: 29191791
[TBL] [Abstract][Full Text] [Related]
18. On the mechanism whereby HI-6 improves neuromuscular function after oxime-resistant acetylcholinesterase inhibition and subsequent impairment of neuromuscular transmission.
Melchers BP; Van der Laaken AL; Van Helden HP
Eur J Pharmacol; 1991 Aug; 200(2-3):331-7. PubMed ID: 1664331
[TBL] [Abstract][Full Text] [Related]
19. Synthesis of a Series of Structurally Diverse MB327 Derivatives and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor.
Rappenglück S; Sichler S; Höfner G; Wein T; Niessen KV; Seeger T; Paintner FF; Worek F; Thiermann H; Wanner KT
ChemMedChem; 2018 Sep; 13(17):1806-1816. PubMed ID: 29974635
[TBL] [Abstract][Full Text] [Related]
20. Pyridinium oximes as cholinesterase reactivators. Structure-activity relationship and efficacy in the treatment of poisoning with organophosphorus compounds.
Jokanović M; Prostran M
Curr Med Chem; 2009; 16(17):2177-88. PubMed ID: 19519385
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]