BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 38731416)

  • 1. Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy-
    Roth HG; Das M; Sulima A; Luo D; Kaska S; Prisinzano TE; Kerr AT; Jacobson AE; Rice KC
    Molecules; 2024 Apr; 29(9):. PubMed ID: 38731416
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans.
    Lutz JA; Sulima A; Gutman ES; Bow EW; Luo D; Kaska S; Prisinzano TE; Paronis CA; Bergman J; Imler GH; Kerr AT; Jacobson AE; Rice KC
    Molecules; 2023 Jun; 28(12):. PubMed ID: 37375350
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A MOR Antagonist with High Potency and Antagonist Efficacy among Diastereomeric C9-Alkyl-Substituted
    Chambers DR; Sulima A; Luo D; Prisinzano TE; Jacobson AE; Rice KC
    Molecules; 2023 Jul; 28(14):. PubMed ID: 37513283
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Journey through Diastereomeric Space: The Design, Synthesis, In Vitro and In Vivo Pharmacological Activity, and Molecular Modeling of Novel Potent Diastereomeric MOR Agonists and Antagonists.
    Chambers DR; Sulima A; Luo D; Prisinzano TE; Goldberg A; Xie B; Shi L; Paronis CA; Bergman J; Nassehi N; Selley DE; Imler GH; Jacobson AE; Rice KC
    Molecules; 2022 Sep; 27(19):. PubMed ID: 36234992
    [TBL] [Abstract][Full Text] [Related]  

  • 5. G-Protein biased opioid agonists: 3-hydroxy-
    Gutman ES; Bow E; Li F; Sulima A; Kaska S; Crowley R; Prisinzano TE; Lee YS; Hassan SA; Imler GH; Deschamps JR; Jacobson AE; Rice KC
    RSC Med Chem; 2020 Aug; 11(8):896-904. PubMed ID: 33479684
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans.
    Li F; Kopajtic TA; Katz JL; Luo D; Prisinzano TE; Imler GH; Deschamps JR; Jacobson AE; Rice KC
    Molecules; 2022 Dec; 27(24):. PubMed ID: 36557961
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Probes for narcotic receptor mediated phenomena. 34. Synthesis and structure-activity relationships of a potent mu-agonist delta-antagonist and an exceedingly potent antinociceptive in the enantiomeric C9-substituted 5-(3-hydroxyphenyl)-N-phenylethylmorphan series.
    Hiebel AC; Lee YS; Bilsky E; Giuvelis D; Deschamps JR; Parrish DA; Aceto MD; May EL; Harris LS; Coop A; Dersch CM; Partilla JS; Rothman RB; Cheng K; Jacobson AE; Rice KC
    J Med Chem; 2007 Aug; 50(16):3765-76. PubMed ID: 17625813
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Probes for narcotic receptor mediated phenomena. 44. Synthesis of an N-substituted 4-hydroxy-5-(3-hydroxyphenyl)morphan with high affinity and selective μ-antagonist activity.
    Iyer MR; Lee YS; Deschamps JR; Dersch CM; Rothman RB; Jacobson AE; Rice KC
    Eur J Med Chem; 2012 Apr; 50():44-54. PubMed ID: 22341895
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Opioid ligands with mixed properties from substituted enantiomeric N-phenethyl-5-phenylmorphans. Synthesis of a micro-agonist delta-antagonist and delta-inverse agonists.
    Cheng K; Kim IJ; Lee MJ; Adah SA; Raymond TJ; Bilsky EJ; Aceto MD; May EL; Harris LS; Coop A; Dersch CM; Rothman RB; Jacobson AE; Rice KC
    Org Biomol Chem; 2007 Apr; 5(8):1177-1190. PubMed ID: 17406716
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent MOR Agonists from 2'-Hydroxy-5,9-dimethyl-
    Das M; Ward GW; Sulima A; Luo D; Prisinzano TE; Imler GH; Kerr AT; Jacobson AE; Rice KC
    Molecules; 2023 Nov; 28(23):. PubMed ID: 38067439
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study.
    Truong PM; Hassan SA; Lee YS; Kopajtic TA; Katz JL; Chadderdon AM; Traynor JR; Deschamps JR; Jacobson AE; Rice KC
    Bioorg Med Chem; 2017 Apr; 25(8):2406-2422. PubMed ID: 28314512
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Intriguing Effects of Substituents in the
    Wang M; Irvin TC; Herdman CA; Hanna RD; Hassan SA; Lee YS; Kaska S; Crowley RS; Prisinzano TE; Withey SL; Paronis CA; Bergman J; Inan S; Geller EB; Adler MW; Kopajtic TA; Katz JL; Chadderdon AM; Traynor JR; Jacobson AE; Rice KC
    Molecules; 2020 Jun; 25(11):. PubMed ID: 32517185
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Probes for narcotic receptor mediated phenomena. 48. C7- and C8-substituted 5-phenylmorphan opioids from diastereoselective alkylation.
    Lim HJ; Dersch CM; Rothman RB; Deschamps JR; Jacobson AE; Rice KC
    Eur J Med Chem; 2013 Sep; 67():335-43. PubMed ID: 23880358
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Probes for narcotic receptor mediated phenomena. 43. Synthesis of the ortho-a and para-a, and improved synthesis and optical resolution of the ortho-b and para-b oxide-bridged phenylmorphans: compounds with moderate to low opioid-receptor affinity.
    Li F; Folk JE; Cheng K; Kurimura M; Deck JA; Deschamps JR; Rothman RB; Dersch CM; Jacobson AE; Rice KC
    Bioorg Med Chem; 2011 Jul; 19(14):4330-7. PubMed ID: 21684752
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, Synthesis, and Structure-Activity Relationship Exploration of Alkyl/Phenylalkyl Piperidine Analogues as Novel Highly Potent and Selective μ Opioid Receptor Agonists.
    Huang H; Li X; Guo W; Zhu C; Qian Y; Shen Q; Xu X; Li W; Wang Y; Fu W
    ACS Chem Neurosci; 2021 Jan; 12(2):285-299. PubMed ID: 32852933
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Probes for narcotic receptor mediated phenomena. 41. Unusual inverse μ-agonists and potent μ-opioid antagonists by modification of the N-substituent in enantiomeric 5-(3-hydroxyphenyl)morphans.
    Cheng K; Lee YS; Rothman RB; Dersch CM; Bittman RW; Jacobson AE; Rice KC
    J Med Chem; 2011 Feb; 54(4):957-69. PubMed ID: 21247164
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans.
    Zezula J; Singer L; Przybył AK; Hashimoto A; Dersch CM; Rothman RB; Deschamps J; Lee YS; Jacobson AE; Rice KC
    Org Biomol Chem; 2008 Aug; 6(16):2868-83. PubMed ID: 18688479
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and Structure-Activity Relationships of 5'-Aryl-14-alkoxypyridomorphinans: Identification of a μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects.
    Vekariya RH; Lei W; Ray A; Saini SK; Zhang S; Molnar G; Barlow D; Karlage KL; Bilsky EJ; Houseknecht KL; Largent-Milnes TM; Streicher JM; Ananthan S
    J Med Chem; 2020 Jul; 63(14):7663-7694. PubMed ID: 32530286
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N-Phenethyl Substitution in 14-Methoxy-N-methylmorphinan-6-ones Turns Selective µ Opioid Receptor Ligands into Dual µ/δ Opioid Receptor Agonists.
    Dumitrascuta M; Bermudez M; Ben Haddou T; Guerrieri E; Schläfer L; Ritsch A; Hosztafi S; Lantero A; Kreutz C; Massotte D; Schmidhammer H; Wolber G; Spetea M
    Sci Rep; 2020 Mar; 10(1):5653. PubMed ID: 32221355
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Highly potent and selective phenylmorphan-based inverse agonists of the opioid delta receptor.
    Thomas JB; Zhang L; Navarro HA; Carroll FI
    J Med Chem; 2006 Sep; 49(18):5597-609. PubMed ID: 16942033
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.