These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 38737295)

  • 1. Unraveling the Connection: Cholesterol, Calcium Signaling, and Neurodegeneration.
    Casas M; Dickson EJ
    Neurosci Insights; 2024; 19():26331055241252772. PubMed ID: 38737295
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NPC1-dependent alterations in K
    Casas M; Murray KD; Hino K; Vierra NC; Simó S; Trimmer JS; Dixon RE; Dickson EJ
    Nat Commun; 2023 Jul; 14(1):4553. PubMed ID: 37507375
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hepatitis C Virus Replication Depends on Endosomal Cholesterol Homeostasis.
    Stoeck IK; Lee JY; Tabata K; Romero-Brey I; Paul D; Schult P; Lohmann V; Kaderali L; Bartenschlager R
    J Virol; 2018 Jan; 92(1):. PubMed ID: 29046459
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Niemann-Pick Type C Disease Reveals a Link between Lysosomal Cholesterol and PtdIns(4,5)P
    Vivas O; Tiscione SA; Dixon RE; Ory DS; Dickson EJ
    Cell Rep; 2019 May; 27(9):2636-2648.e4. PubMed ID: 31141688
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular dynamics study with mutation shows that N-terminal domain structural re-orientation in Niemann-Pick type C1 is required for proper alignment of cholesterol transport.
    Yoon HJ; Jeong H; Lee HH; Jang S
    J Neurochem; 2021 Mar; 156(6):967-978. PubMed ID: 32880929
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C.
    Davis OB; Shin HR; Lim CY; Wu EY; Kukurugya M; Maher CF; Perera RM; Ordonez MP; Zoncu R
    Dev Cell; 2021 Feb; 56(3):260-276.e7. PubMed ID: 33308480
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1.
    Prabhu AV; Kang I; De Pace R; Wassif CA; Fujiwara H; Kell P; Jiang X; Ory DS; Bonifacino JS; Ward ME; Porter FD
    BMC Biol; 2021 Oct; 19(1):218. PubMed ID: 34592985
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium.
    Lloyd-Evans E; Morgan AJ; He X; Smith DA; Elliot-Smith E; Sillence DJ; Churchill GC; Schuchman EH; Galione A; Platt FM
    Nat Med; 2008 Nov; 14(11):1247-55. PubMed ID: 18953351
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantitative, Label-Free Proteomics in the Symptomatic Niemann-Pick, Type C1 Mouse Model Using Standard Flow Liquid Chromatography and Thermal Focusing Electrospray Ionization.
    Pergande MR; Nguyen TTA; Haney-Ball C; Davidson CD; Cologna SM
    Proteomics; 2019 May; 19(9):e1800432. PubMed ID: 30888112
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endo-lysosomal dysfunction and neuronal-glial crosstalk in Niemann-Pick type C disease.
    Malara M; Prestel M; Tahirovic S
    Philos Trans R Soc Lond B Biol Sci; 2024 Apr; 379(1899):20220388. PubMed ID: 38368932
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Niemann-Pick C1 protein: obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization.
    Watari H; Blanchette-Mackie EJ; Dwyer NK; Glick JM; Patel S; Neufeld EB; Brady RO; Pentchev PG; Strauss JF
    Proc Natl Acad Sci U S A; 1999 Feb; 96(3):805-10. PubMed ID: 9927649
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The point mutation of the cholesterol trafficking membrane protein NPC1 may affect its proper function in more than a single step: Molecular dynamics simulation study.
    Yoon HJ; Jeong J; Kim G; Lee HH; Jang S
    Comput Biol Chem; 2022 Aug; 99():107725. PubMed ID: 35850050
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Different Trafficking Phenotypes of Niemann-Pick C1 Gene Mutations Correlate with Various Alterations in Lipid Storage, Membrane Composition and Miglustat Amenability.
    Brogden G; Shammas H; Walters F; Maalouf K; Das AM; Naim HY; Rizk S
    Int J Mol Sci; 2020 Mar; 21(6):. PubMed ID: 32204338
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting defective sphingosine kinase 1 in Niemann-Pick type C disease with an activator mitigates cholesterol accumulation.
    Newton J; Palladino END; Weigel C; Maceyka M; Gräler MH; Senkal CE; Enriz RD; Marvanova P; Jampilek J; Lima S; Milstien S; Spiegel S
    J Biol Chem; 2020 Jul; 295(27):9121-9133. PubMed ID: 32385114
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impaired Retromer Function in Niemann-Pick Type C Disease Is Dependent on Intracellular Cholesterol Accumulation.
    Dominko K; Rastija A; Sobocanec S; Vidatic L; Meglaj S; Lovincic Babic A; Hutter-Paier B; Colombo AV; Lichtenthaler SF; Tahirovic S; Hecimovic S
    Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948052
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Localization of Niemann-Pick C1 protein in astrocytes: implications for neuronal degeneration in Niemann- Pick type C disease.
    Patel SC; Suresh S; Kumar U; Hu CY; Cooney A; Blanchette-Mackie EJ; Neufeld EB; Patel RC; Brady RO; Patel YC; Pentchev PG; Ong WY
    Proc Natl Acad Sci U S A; 1999 Feb; 96(4):1657-62. PubMed ID: 9990080
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Niemann-Pick C1 functions independently of Niemann-Pick C2 in the initial stage of retrograde transport of membrane-impermeable lysosomal cargo.
    Goldman SD; Krise JP
    J Biol Chem; 2010 Feb; 285(7):4983-94. PubMed ID: 20007703
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1.
    Mundy DI; Lopez AM; Posey KS; Chuang JC; Ramirez CM; Scherer PE; Turley SD
    Biochim Biophys Acta; 2014 Jul; 1841(7):995-1002. PubMed ID: 24747682
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation of the Potential Role of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Niemann-Pick Disease, Type C1.
    Cawley NX; Lyons AT; Abebe D; Wassif CA; Porter FD
    Int J Mol Sci; 2020 Mar; 21(7):. PubMed ID: 32244519
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Disease-associated mutations in Niemann-Pick type C1 alter ER calcium signaling and neuronal plasticity.
    Tiscione SA; Vivas O; Ginsburg KS; Bers DM; Ory DS; Santana LF; Dixon RE; Dickson EJ
    J Cell Biol; 2019 Dec; 218(12):4141-4156. PubMed ID: 31601621
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.