198 related articles for article (PubMed ID: 38741019)
21. Atypical ubiquitination by E3 ligase WWP1 inhibits the proteasome-mediated degradation of mutant huntingtin.
Lin L; Jin Z; Tan H; Xu Q; Peng T; Li H
Brain Res; 2016 Jul; 1643():103-12. PubMed ID: 27107943
[TBL] [Abstract][Full Text] [Related]
22. Mutant Huntingtin Is Cleared from the Brain via Active Mechanisms in Huntington Disease.
Caron NS; Banos R; Yanick C; Aly AE; Byrne LM; Smith ED; Xie Y; Smith SEP; Potluri N; Findlay Black H; Casal L; Ko S; Cheung D; Kim H; Seong IS; Wild EJ; Song JJ; Hayden MR; Southwell AL
J Neurosci; 2021 Jan; 41(4):780-796. PubMed ID: 33310753
[TBL] [Abstract][Full Text] [Related]
23. Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.
Wellington CL; Ellerby LM; Gutekunst CA; Rogers D; Warby S; Graham RK; Loubser O; van Raamsdonk J; Singaraja R; Yang YZ; Gafni J; Bredesen D; Hersch SM; Leavitt BR; Roy S; Nicholson DW; Hayden MR
J Neurosci; 2002 Sep; 22(18):7862-72. PubMed ID: 12223539
[TBL] [Abstract][Full Text] [Related]
24. Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.
Onur TS; Laitman A; Zhao H; Keyho R; Kim H; Wang J; Mair M; Wang H; Li L; Perez A; de Haro M; Wan YW; Allen G; Lu B; Al-Ramahi I; Liu Z; Botas J
Elife; 2021 Apr; 10():. PubMed ID: 33871358
[TBL] [Abstract][Full Text] [Related]
25. Development of mAb-based polyglutamine-dependent and polyglutamine length-independent huntingtin quantification assays with cross-site validation.
Fischer DF; Dijkstra S; Lo K; Suijker J; Correia ACP; Naud P; Poirier M; Tessari MA; Boogaard I; Flynn G; Visser M; Lamers MBAC; McAllister G; Munoz-Sanjuan I; Macdonald D
PLoS One; 2022; 17(4):e0266812. PubMed ID: 35395060
[TBL] [Abstract][Full Text] [Related]
26. Pathogenic cellular phenotypes are germline transmissible in a transgenic primate model of Huntington's disease.
Putkhao K; Kocerha J; Cho IK; Yang J; Parnpai R; Chan AW
Stem Cells Dev; 2013 Apr; 22(8):1198-205. PubMed ID: 23190281
[TBL] [Abstract][Full Text] [Related]
27. Mutant Huntingtin stalls ribosomes and represses protein synthesis in a cellular model of Huntington disease.
Eshraghi M; Karunadharma PP; Blin J; Shahani N; Ricci EP; Michel A; Urban NT; Galli N; Sharma M; Ramírez-Jarquín UN; Florescu K; Hernandez J; Subramaniam S
Nat Commun; 2021 Mar; 12(1):1461. PubMed ID: 33674575
[TBL] [Abstract][Full Text] [Related]
28. Analysis of mutant and total huntingtin expression in Huntington's disease murine models.
Fodale V; Pintauro R; Daldin M; Altobelli R; Spiezia MC; Bisbocci M; Macdonald D; Bresciani A
Sci Rep; 2020 Dec; 10(1):22137. PubMed ID: 33335120
[TBL] [Abstract][Full Text] [Related]
29. Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease.
Reddy PH; Charles V; Williams M; Miller G; Whetsell WO; Tagle DA
Philos Trans R Soc Lond B Biol Sci; 1999 Jun; 354(1386):1035-45. PubMed ID: 10434303
[TBL] [Abstract][Full Text] [Related]
30. Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates.
Herrmann F; Hessmann M; Schaertl S; Berg-Rosseburg K; Brown CJ; Bursow G; Chiki A; Ebneth A; Gehrmann M; Hoeschen N; Hotze M; Jahn S; Johnson PD; Khetarpal V; Kiselyov A; Kottig K; Ladewig S; Lashuel H; Letschert S; Mills MR; Petersen K; Prime ME; Scheich C; Schmiedel G; Wityak J; Liu L; Dominguez C; Muñoz-Sanjuán I; Bard JA
Sci Rep; 2021 Sep; 11(1):17977. PubMed ID: 34504195
[TBL] [Abstract][Full Text] [Related]
31. 14-3-3zeta is indispensable for aggregate formation of polyglutamine-expanded huntingtin protein.
Omi K; Hachiya NS; Tanaka M; Tokunaga K; Kaneko K
Neurosci Lett; 2008 Jan; 431(1):45-50. PubMed ID: 18078716
[TBL] [Abstract][Full Text] [Related]
32. Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects.
Hakim-Eshed V; Boulos A; Cohen-Rosenzweig C; Yu-Taeger L; Ziv T; Kwon YT; Riess O; Phuc Nguyen HH; Ziv NE; Ciechanover A
Proc Natl Acad Sci U S A; 2020 Aug; 117(31):18661-18669. PubMed ID: 32675242
[TBL] [Abstract][Full Text] [Related]
33. Ellagic acid rescues motor and cognitive deficits in the R6/2 mouse model of Huntington's disease by lowering mutant huntingtin protein.
Sun X; Zhu J; Sun XY; Ji M; Yu XL; Liu RT
Food Funct; 2020 Feb; 11(2):1334-1348. PubMed ID: 32043503
[TBL] [Abstract][Full Text] [Related]
34. The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients.
Koyuncu S; Saez I; Lee HJ; Gutierrez-Garcia R; Pokrzywa W; Fatima A; Hoppe T; Vilchez D
Nat Commun; 2018 Jul; 9(1):2886. PubMed ID: 30038412
[TBL] [Abstract][Full Text] [Related]
35. Artificial miRNAs targeting CAG repeat expansion in ORFs cause rapid deadenylation and translation inhibition of mutant transcripts.
Ciesiolka A; Stroynowska-Czerwinska A; Joachimiak P; Ciolak A; Kozlowska E; Michalak M; Dabrowska M; Olejniczak M; Raczynska KD; Zielinska D; Wozna-Wysocka M; Krzyzosiak WJ; Fiszer A
Cell Mol Life Sci; 2021 Feb; 78(4):1577-1596. PubMed ID: 32696070
[TBL] [Abstract][Full Text] [Related]
36. CAG RNAs induce DNA damage and apoptosis by silencing
Peng S; Guo P; Lin X; An Y; Sze KH; Lau MHY; Chen ZS; Wang Q; Li W; Sun JK; Ma SY; Chan TF; Lau KF; Ngo JCK; Kwan KM; Wong CH; Lam SL; Zimmerman SC; Tuccinardi T; Zuo Z; Au-Yeung HY; Chow HM; Chan HYE
Proc Natl Acad Sci U S A; 2021 May; 118(19):. PubMed ID: 33947817
[TBL] [Abstract][Full Text] [Related]
37. Aggregation landscapes of Huntingtin exon 1 protein fragments and the critical repeat length for the onset of Huntington's disease.
Chen M; Wolynes PG
Proc Natl Acad Sci U S A; 2017 Apr; 114(17):4406-4411. PubMed ID: 28400517
[TBL] [Abstract][Full Text] [Related]
38. Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes.
Chou SY; Weng JY; Lai HL; Liao F; Sun SH; Tu PH; Dickson DW; Chern Y
J Neurosci; 2008 Mar; 28(13):3277-90. PubMed ID: 18367595
[TBL] [Abstract][Full Text] [Related]
39. HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington's disease mice.
Chen L; Qin Y; Guo T; Zhu W; Lin J; Xing T; Duan X; Zhang Y; Ruan E; Li X; Yin P; Li S; Li XJ; Yang S
Cell Death Dis; 2024 May; 15(5):337. PubMed ID: 38744826
[TBL] [Abstract][Full Text] [Related]
40. A toxic mutant huntingtin species is resistant to selective autophagy.
Fu Y; Wu P; Pan Y; Sun X; Yang H; Difiglia M; Lu B
Nat Chem Biol; 2017 Nov; 13(11):1152-1154. PubMed ID: 28869595
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]