These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 38744987)

  • 1. The β-subunit of tryptophan synthase is a latent tyrosine synthase.
    Almhjell PJ; Johnston KE; Porter NJ; Kennemur JL; Bhethanabotla VC; Ducharme J; Arnold FH
    Nat Chem Biol; 2024 Aug; 20(8):1086-1093. PubMed ID: 38744987
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of β-Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase.
    Herger M; van Roye P; Romney DK; Brinkmann-Chen S; Buller AR; Arnold FH
    J Am Chem Soc; 2016 Jul; 138(27):8388-91. PubMed ID: 27355405
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB.
    Michalska K; Wellington S; Maltseva N; Jedrzejczak R; Selem-Mojica N; Rosas-Becerra LR; Barona-Gómez F; Hung DT; Joachimiak A
    Protein Sci; 2021 Sep; 30(9):1904-1918. PubMed ID: 34107106
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reactions of O-acyl-L-serines with tryptophanase, tyrosine phenol-lyase, and tryptophan synthase.
    Phillips RS
    Arch Biochem Biophys; 1987 Jul; 256(1):302-10. PubMed ID: 3111376
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of tyrosine ring fluorination on rates and equilibria of formation of intermediates in the reactions of carbon-carbon lyases.
    Phillips RS; Von Tersch RL; Secundo F
    Eur J Biochem; 1997 Mar; 244(2):658-63. PubMed ID: 9119037
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Spatial structure and mechanism of tyrosine phenol-lyase and tryptophan indole-lyase].
    Demidkina TV; Anston AA; Faleev NG; Phillips RS; Zakomyrdina LN
    Mol Biol (Mosk); 2009; 43(2):295-308. PubMed ID: 19425498
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tryptophan Synthase Uses an Atypical Mechanism To Achieve Substrate Specificity.
    Buller AR; van Roye P; Murciano-Calles J; Arnold FH
    Biochemistry; 2016 Dec; 55(51):7043-7046. PubMed ID: 27935677
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation.
    Buller AR; Brinkmann-Chen S; Romney DK; Herger M; Murciano-Calles J; Arnold FH
    Proc Natl Acad Sci U S A; 2015 Nov; 112(47):14599-604. PubMed ID: 26553994
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Direct Enzymatic Synthesis of a Deep-Blue Fluorescent Noncanonical Amino Acid from Azulene and Serine.
    Watkins EJ; Almhjell PJ; Arnold FH
    Chembiochem; 2020 Jan; 21(1-2):80-83. PubMed ID: 31513332
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Severing of a hydrogen bond disrupts amino acid networks in the catalytically active state of the alpha subunit of tryptophan synthase.
    Axe JM; O'Rourke KF; Kerstetter NE; Yezdimer EM; Chan YM; Chasin A; Boehr DD
    Protein Sci; 2015 Apr; 24(4):484-94. PubMed ID: 25377949
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes.
    Phillips RS; Demidkina TV; Zakomirdina LN; Bruno S; Ronda L; Mozzarelli A
    J Biol Chem; 2002 Jun; 277(24):21592-7. PubMed ID: 11934889
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Scalable continuous evolution for the generation of diverse enzyme variants encompassing promiscuous activities.
    Rix G; Watkins-Dulaney EJ; Almhjell PJ; Boville CE; Arnold FH; Liu CC
    Nat Commun; 2020 Nov; 11(1):5644. PubMed ID: 33159067
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of aminoacrylate intermediates of pyridoxal-5'-phosphate dependent enzymes.
    Phillips RS; Bauer O
    Methods Enzymol; 2023; 685():199-224. PubMed ID: 37245902
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An Engineered Tryptophan Synthase Opens New Enzymatic Pathways to β-Methyltryptophan and Derivatives.
    Francis D; Winn M; Latham J; Greaney MF; Micklefield J
    Chembiochem; 2017 Feb; 18(4):382-386. PubMed ID: 28005309
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Engineered Biosynthesis of β-Alkyl Tryptophan Analogues.
    Boville CE; Scheele RA; Koch P; Brinkmann-Chen S; Buller AR; Arnold FH
    Angew Chem Int Ed Engl; 2018 Nov; 57(45):14764-14768. PubMed ID: 30215880
    [TBL] [Abstract][Full Text] [Related]  

  • 16. pH dependence of tryptophan synthase catalytic mechanism: I. The first stage, the beta-elimination reaction.
    Schiaretti F; Bettati S; Viappiani C; Mozzarelli A
    J Biol Chem; 2004 Jul; 279(28):29572-82. PubMed ID: 15117965
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tailoring Tryptophan Synthase TrpB for Selective Quaternary Carbon Bond Formation.
    Dick M; Sarai NS; Martynowycz MW; Gonen T; Arnold FH
    J Am Chem Soc; 2019 Dec; 141(50):19817-19822. PubMed ID: 31747522
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tryptophan Synthase: Biocatalyst Extraordinaire.
    Watkins-Dulaney E; Straathof S; Arnold F
    Chembiochem; 2021 Jan; 22(1):5-16. PubMed ID: 32677310
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Site-directed mutagenesis switching a dimethylallyl tryptophan synthase to a specific tyrosine C3-prenylating enzyme.
    Fan A; Zocher G; Stec E; Stehle T; Li SM
    J Biol Chem; 2015 Jan; 290(3):1364-73. PubMed ID: 25477507
    [TBL] [Abstract][Full Text] [Related]  

  • 20. M379A Mutant Tyrosine Phenol-lyase from Citrobacter freundii Has Altered Conformational Dynamics.
    Phillips RS; Jones B; Nash S
    Chembiochem; 2022 Jul; 23(13):e202200028. PubMed ID: 35577764
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.