BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 38754805)

  • 21. Genotoxicity assessments of N-nitrosoethylisopropylamine (NEIPA) and N-nitrosodiisopropylamine (NDIPA) in the C57BL/6J mouse.
    Ye Q; Geng X; Jiang H; Qin C; Wu H; Wang S; Wen H
    Mutat Res Genet Toxicol Environ Mutagen; 2024; 896():503763. PubMed ID: 38821676
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Use of less-than-lifetime (LTL) durational limits for nitrosamines: Case study of N-Nitrosodiethylamine (NDEA).
    Bercu JP; Masuda-Herrera M; Johnson G; Czich A; Glowienke S; Kenyon M; Thomas R; Ponting DJ; White A; Cross K; Waechter F; Rodrigues MAC
    Regul Toxicol Pharmacol; 2021 Jul; 123():104926. PubMed ID: 33862169
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Current status and prospects of development of analytical methods for determining nitrosamine and N-nitroso impurities in pharmaceuticals.
    Wichitnithad W; Nantaphol S; Noppakhunsomboon K; Thitikornpong W; Rojsitthisak P
    Talanta; 2023 Mar; 254():124102. PubMed ID: 36470020
    [TBL] [Abstract][Full Text] [Related]  

  • 24. MELANOMA AND DYSPLASTIC NEVI DEVELOPMENT AFTER RANITIDINE/RILMENIDINE/МOXONIDINE, LERCANIDIPINE, ROSUVASTATIN AND VERAPAMIL/TRANDOLAPRIL - NEW DATA/CASE SERIES. THE POTENTIAL ROLE OF NITROSAMINE/NDSRIS CONTAMINATION IN POLYMEDICATION AS SUBSTANTIAL SKIN CANCER TRIGGERING FACTOR.
    Tchernev G; Naydekova N
    Georgian Med News; 2023 Nov; (344):152-158. PubMed ID: 38236117
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Mutagenic impurities in pharmaceuticals: A critical assessment of the cohort of concern with a focus on N-nitrosamines.
    Snodin DJ
    Regul Toxicol Pharmacol; 2023 Jun; 141():105403. PubMed ID: 37116739
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Meeting Report: N-Nitrosamine Impurity Control Strategies in the Pharmaceutical and Biotechnology Industries.
    Roberts SW; Lennard A; Mohan G; Bernstein J; Cauchon NS; Cole S; Curristin N; Huynh-Ba K; Kolz CN; Murti C; Tang K
    AAPS J; 2021 Jul; 23(4):94. PubMed ID: 34258657
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Tolerability of risk: A commentary on the nitrosamine contamination issue.
    Elder DP; Johnson GE; Snodin DJ
    J Pharm Sci; 2021 Jun; 110(6):2311-2328. PubMed ID: 33705731
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The Landscape of Potential Small and Drug Substance Related Nitrosamines in Pharmaceuticals.
    Schlingemann J; Burns MJ; Ponting DJ; Martins Avila C; Romero NE; Jaywant MA; Smith GF; Ashworth IW; Simon S; Saal C; Wilk A
    J Pharm Sci; 2023 May; 112(5):1287-1304. PubMed ID: 36402198
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A deep dive into historical Ames study data for N-nitrosamine compounds.
    Tennant RE; Ponting DJ; Thresher A
    Regul Toxicol Pharmacol; 2023 Sep; 143():105460. PubMed ID: 37495012
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Potentially mutagenic impurities: analysis of structural classes and carcinogenic potencies of chemical intermediates in pharmaceutical syntheses supports alternative methods to the default TTC for calculating safe levels of impurities.
    Galloway SM; Vijayaraj Reddy M; McGettigan K; Gealy R; Bercu J
    Regul Toxicol Pharmacol; 2013 Aug; 66(3):326-35. PubMed ID: 23688841
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mutagenic impurities in pharmaceuticals: a critique of the derivation of the cancer TTC (Threshold of Toxicological Concern) and recommendations for structural-class-based limits.
    Snodin DJ; McCrossen SD
    Regul Toxicol Pharmacol; 2013 Nov; 67(2):299-316. PubMed ID: 23988886
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Determination of compound-specific acceptable daily intakes for 11 mutagenic carcinogens used in pharmaceutical synthesis.
    Ellis P; Kenyon M; Dobo K
    Regul Toxicol Pharmacol; 2013 Mar; 65(2):201-13. PubMed ID: 23228434
    [TBL] [Abstract][Full Text] [Related]  

  • 33. NITROSAMINES IN COMMONLY PRESCRIBED ANTIHYPERTENSIVES AND THE (UN)CONTROLLED DRUG-INDUCED SKIN CANCER: SIMULTANEOUS DEVELOPMENT OF CUTANEOUS MELANOMA AND MULTIPLE BCC AFTER CONCOMITANT ADMINISTRATION OF BISOPROLOL AND FUROSEMIDE.
    Tchernev G
    Georgian Med News; 2023 Sep; (342):149-151. PubMed ID: 37991971
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Bumetanide as a Model NDSRI Substrate: N-nitrosobumetanide Impurity Formation and its Inhibition in Bumetanide Tablets.
    Shakleya D; Asmelash B; Alayoubi A; Abrigo N; Mohammad A; Wang J; Zhang J; Yang J; Marzan TA; Li D; Shaklah M; Alsharif FM; Desai S; Faustino PJ; Ashraf M; O'Connor T; Vera M; Raw A; Sayeed VA; Keire D
    J Pharm Sci; 2023 Dec; 112(12):3075-3087. PubMed ID: 37364772
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450s.
    Li X; He X; Le Y; Guo X; Bryant MS; Atrakchi AH; McGovern TJ; Davis-Bruno KL; Keire DA; Heflich RH; Mei N
    Arch Toxicol; 2022 Nov; 96(11):3077-3089. PubMed ID: 35882637
    [TBL] [Abstract][Full Text] [Related]  

  • 36. What Makes a Potent Nitrosamine? Statistical Validation of Expert-Derived Structure-Activity Relationships.
    Thomas R; Tennant RE; Oliveira AAF; Ponting DJ
    Chem Res Toxicol; 2022 Nov; 35(11):1997-2013. PubMed ID: 36302501
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Regulatory Experiences with Root Causes and Risk Factors for Nitrosamine Impurities in Pharmaceuticals.
    Horne S; Vera MD; Nagavelli LR; Sayeed VA; Heckman L; Johnson D; Berger D; Yip YY; Krahn CL; Sizukusa LO; Rocha NFM; Bream RN; Ludwig J; Keire DA; Condran G
    J Pharm Sci; 2023 May; 112(5):1166-1182. PubMed ID: 36599405
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Nitrosamine Impurities in Angiotensin Receptor Blockers.
    Shephard EA; Nawarskas JJ
    Cardiol Rev; 2020; 28(5):262-265. PubMed ID: 32467427
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Strategies for Assessing Acceptable Intakes for Novel
    Ponting DJ; Dobo KL; Kenyon MO; Kalgutkar AS
    J Med Chem; 2022 Dec; 65(23):15584-15607. PubMed ID: 36441966
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Nitrosamine Contamination in Pharmaceuticals: Threat, Impact, and Control.
    Tuesuwan B; Vongsutilers V
    J Pharm Sci; 2021 Sep; 110(9):3118-3128. PubMed ID: 33989680
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.