These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 38762979)

  • 1. Synthesis and biological evaluation of orally active anti-Trypanosoma agents.
    Salem FM; Martin WR; Zhao X; Adbus Sayeed SK; Ighneim S; Greene M; Mohamed E; Orahoske CM; Zhang W; Li B; Su B
    Bioorg Med Chem; 2024 Jun; 107():117751. PubMed ID: 38762979
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lead optimization of selective tubulin inhibitors as anti-trypanosomal agents.
    Zhao A; Li Y; Orahoske CM; Schnur B; Sabbagh A; Zhang W; Li B; Su B
    Bioorg Med Chem; 2019 Apr; 27(8):1517-1528. PubMed ID: 30833159
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of selective tubulin inhibitors as anti-trypanosomal agents.
    Bobba V; Nanavaty V; Idippily ND; Zhao A; Li B; Su B
    Bioorg Med Chem; 2017 Jun; 25(12):3215-3222. PubMed ID: 28428042
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Orally Active and Selective Tubulin Inhibitors as Anti-Trypanosome Agents.
    Nanavaty V; Lama R; Sandhu R; Zhong B; Kulman D; Bobba V; Zhao A; Li B; Su B
    PLoS One; 2016; 11(1):e0146289. PubMed ID: 26771307
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of selective tubulin inhibitors as potential anti-trypanosomal agents.
    Lama R; Sandhu R; Zhong B; Li B; Su B
    Bioorg Med Chem Lett; 2012 Sep; 22(17):5508-16. PubMed ID: 22850214
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Optimization of physicochemical properties for 4-anilinoquinazoline inhibitors of trypanosome proliferation.
    Woodring JL; Bachovchin KA; Brady KG; Gallerstein MF; Erath J; Tanghe S; Leed SE; Rodriguez A; Mensa-Wilmot K; Sciotti RJ; Pollastri MP
    Eur J Med Chem; 2017 Dec; 141():446-459. PubMed ID: 29049963
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of imidamide analogs as selective anti-trypanosomal agents.
    Bobba V; Li Y; Afrin M; Dano R; Zhang W; Li B; Su B
    Bioorg Med Chem; 2022 May; 61():116740. PubMed ID: 35396128
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals.
    Veerman J; van den Bergh T; Orrling KM; Jansen C; Cos P; Maes L; Chatelain E; Ioset JR; Edink EE; Tenor H; Seebeck T; de Esch I; Leurs R; Sterk GJ
    Bioorg Med Chem; 2016 Apr; 24(7):1573-81. PubMed ID: 26935942
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Brain-Penetrant Triazolopyrimidine and Phenylpyrimidine Microtubule Stabilizers as Potential Leads to Treat Human African Trypanosomiasis.
    Monti L; Wang SC; Oukoloff K; Smith AB; Brunden KR; Caffrey CR; Ballatore C
    ChemMedChem; 2018 Sep; 13(17):1751-1754. PubMed ID: 29969537
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel pyrrolobenzoxaboroles: design, synthesis, and biological evaluation against Trypanosoma brucei.
    Wu P; Zhang J; Meng Q; Nare B; Jacobs RT; Zhou H
    Eur J Med Chem; 2014 Jun; 81():59-75. PubMed ID: 24826816
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis.
    Klug DM; Mavrogiannaki EM; Forbes KC; Silva L; Diaz-Gonzalez R; Pérez-Moreno G; Ceballos-Pérez G; Garcia-Hernández R; Bosch-Navarrete C; Cordón-Obras C; Gómez-Liñán C; Saura A; Momper JD; Martinez-Martinez MS; Manzano P; Syed A; El-Sakkary N; Caffrey CR; Gamarro F; Ruiz-Perez LM; Gonzalez Pacanowska D; Ferrins L; Navarro M; Pollastri MP
    J Med Chem; 2021 Jul; 64(13):9404-9430. PubMed ID: 34156862
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of halo-nitrobenzamides with potential application against human African trypanosomiasis.
    Hwang JY; Smithson D; Connelly M; Maier J; Zhu F; Guy KR
    Bioorg Med Chem Lett; 2010 Jan; 20(1):149-52. PubMed ID: 19963377
    [TBL] [Abstract][Full Text] [Related]  

  • 13. From on-target to off-target activity: identification and optimisation of Trypanosoma brucei GSK3 inhibitors and their characterisation as anti-Trypanosoma brucei drug discovery lead molecules.
    Woodland A; Grimaldi R; Luksch T; Cleghorn LA; Ojo KK; Van Voorhis WC; Brenk R; Frearson JA; Gilbert IH; Wyatt PG
    ChemMedChem; 2013 Jul; 8(7):1127-37. PubMed ID: 23776181
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of trypanosome alternative oxidase without its N-terminal mitochondrial targeting signal (ΔMTS-TAO) by cationic and non-cationic 4-hydroxybenzoate and 4-alkoxybenzaldehyde derivatives active against T. brucei and T. congolense.
    Ebiloma GU; Ayuga TD; Balogun EO; Gil LA; Donachie A; Kaiser M; Herraiz T; Inaoka DK; Shiba T; Harada S; Kita K; de Koning HP; Dardonville C
    Eur J Med Chem; 2018 Apr; 150():385-402. PubMed ID: 29544150
    [TBL] [Abstract][Full Text] [Related]  

  • 15. African trypanosomiasis: Synthesis & SAR enabling novel drug discovery of ubiquinol mimics for trypanosome alternative oxidase.
    West RA; O'Doherty OG; Askwith T; Atack J; Beswick P; Laverick J; Paradowski M; Pennicott LE; Rao SPS; Williams G; Ward SE
    Eur J Med Chem; 2017 Dec; 141():676-689. PubMed ID: 29107420
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Anti-trypanosomal activity of doubly modified salinomycin derivatives.
    Antoszczak M; Steverding D; Sulik M; Janczak J; Huczyński A
    Eur J Med Chem; 2019 Jul; 173():90-98. PubMed ID: 30986574
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors.
    Brand S; Cleghorn LA; McElroy SP; Robinson DA; Smith VC; Hallyburton I; Harrison JR; Norcross NR; Spinks D; Bayliss T; Norval S; Stojanovski L; Torrie LS; Frearson JA; Brenk R; Fairlamb AH; Ferguson MA; Read KD; Wyatt PG; Gilbert IH
    J Med Chem; 2012 Jan; 55(1):140-52. PubMed ID: 22148754
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bistacrines as potential antitrypanosomal agents.
    Schmidt I; Göllner S; Fuß A; Stich A; Kucharski A; Schirmeister T; Katzowitsch E; Bruhn H; Miliu A; Krauth-Siegel RL; Holzgrabe U
    Bioorg Med Chem; 2017 Aug; 25(16):4526-4531. PubMed ID: 28698054
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hit-to-Lead Optimization of Benzoxazepinoindazoles As Human African Trypanosomiasis Therapeutics.
    Klug DM; Tschiegg L; Diaz R; Rojas-Barros D; Perez-Moreno G; Ceballos G; García-Hernández R; Martinez-Martinez MS; Manzano P; Ruiz LM; Caffrey CR; Gamarro F; Pacanowska DG; Ferrins L; Navarro M; Pollastri MP
    J Med Chem; 2020 Mar; 63(5):2527-2546. PubMed ID: 31670951
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel 1,2-dihydroquinazolin-2-ones: Design, synthesis, and biological evaluation against Trypanosoma brucei.
    Pham T; Walden M; Butler C; Diaz-Gonzalez R; Pérez-Moreno G; Ceballos-Pérez G; Gomez-Pérez V; García-Hernández R; Zecca H; Krakoff E; Kopec B; Ichire O; Mackenzie C; Pitot M; Ruiz LM; Gamarro F; González-Pacanowska D; Navarro M; Dounay AB
    Bioorg Med Chem Lett; 2017 Aug; 27(16):3629-3635. PubMed ID: 28729055
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.