These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 38772136)

  • 1. Novel 4-triazole phenyl amide (4-TPA) molecules: Potent promoters of α-synuclein fibril disassembly.
    Qiu C; Wei R; Bian J; Lin X; Bai T; He J; Guo X; Chu Y
    Eur J Med Chem; 2024 Jul; 273():116490. PubMed ID: 38772136
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson's disease.
    Vittorio S; Adornato I; Gitto R; Peña-Díaz S; Ventura S; De Luca L
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):1727-1735. PubMed ID: 32924648
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of styrylaniline derivatives as novel alpha-synuclein aggregates ligands.
    Bian J; Liu YQ; He J; Lin X; Qiu CY; Yu WB; Shen Y; Zhu ZY; Ye DY; Wang J; Chu Y
    Eur J Med Chem; 2021 Dec; 226():113887. PubMed ID: 34624824
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects.
    AlNajjar YT; Gabr M; ElHady AK; Salah M; Wilms G; Abadi AH; Becker W; Abdel-Halim M; Engel M
    Eur J Med Chem; 2022 Jan; 227():113911. PubMed ID: 34710745
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 1-Indanone and 1,3-indandione Derivatives as Ligands for Misfolded α-Synuclein Aggregates.
    Sun X; Admane P; Starosolski ZA; Eriksen JL; Annapragada AV; Tanifum EA
    ChemMedChem; 2022 Jan; 17(2):e202100611. PubMed ID: 34704363
    [TBL] [Abstract][Full Text] [Related]  

  • 6. C9-Functionalized Doxycycline Analogs as Drug Candidates to Prevent Pathological α-Synuclein Aggregation and Neuroinflammation in Parkinson's Disease Degeneration.
    Rose C; Tomas-Grau RH; Zabala B; Michel PP; Brunel JM; Chehín R; Raisman-Vozari R; Ferrié L; Figadère B
    ChemMedChem; 2024 Jun; 19(12):e202300597. PubMed ID: 38526011
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and structure-activity evaluation of novel 2-pyridone-based inhibitors of α-synuclein aggregation with potentially improved BBB permeability.
    Mahía A; Peña-Díaz S; Navarro S; José Galano-Frutos J; Pallarés I; Pujols J; Díaz-de-Villegas MD; Gálvez JA; Ventura S; Sancho J
    Bioorg Chem; 2021 Dec; 117():105472. PubMed ID: 34775206
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel multifunctional dopamine D
    Luo D; Sharma H; Yedlapudi D; Antonio T; Reith MEA; Dutta AK
    Bioorg Med Chem; 2016 Nov; 24(21):5088-5102. PubMed ID: 27591013
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In silico drug repositioning of FDA-approved drugs to predict new inhibitors for alpha-synuclein aggregation.
    Jafaripour SS; Gharaghani S; Nazarshodeh E; Haider S; Saboury AA
    Comput Biol Chem; 2020 Oct; 88():107308. PubMed ID: 32650066
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacological inhibition and knockdown of O-GlcNAcase reduces cellular internalization of α-synuclein preformed fibrils.
    Tavassoly O; Yue J; Vocadlo DJ
    FEBS J; 2021 Jan; 288(2):452-470. PubMed ID: 32365408
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, immunocytochemistry evaluation, and molecular docking investigation of several 4-aminopyridine derivatives as potential neuroprotective agents for treating Parkinson's disease.
    Li S; Wei D; Mao Z; Chen L; Yan X; Li Y; Dong S; Wang D
    Bioorg Chem; 2017 Aug; 73():63-75. PubMed ID: 28618343
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Multi-target-directed triazole derivatives as promising agents for the treatment of Alzheimer's disease.
    Kaur A; Mann S; Kaur A; Priyadarshi N; Goyal B; Singhal NK; Goyal D
    Bioorg Chem; 2019 Jun; 87():572-584. PubMed ID: 30928879
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro inhibition of α-Synuclein aggregation and disaggregation of preformed fibers by polyphenol hybrids with 2-conjugated benzothiazole.
    Zhao YD; Zhang W; Xing LZ; Xu J; Shi WM; Zhang YX
    Bioorg Med Chem Lett; 2024 Jun; 105():129752. PubMed ID: 38631541
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Complex of EGCG with Cu(II) Suppresses Amyloid Aggregation and Cu(II)-Induced Cytotoxicity of α-Synuclein.
    Teng Y; Zhao J; Ding L; Ding Y; Zhou P
    Molecules; 2019 Aug; 24(16):. PubMed ID: 31416122
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Anethole attenuates motor dysfunctions, striatal neuronal activity deficiency and blood brain barrier permeability by decreasing striatal α-synuclein and oxidative stress in rotenone-induced Parkinson's disease of male rats.
    Moradi Vastegani S; Khoshnam SE; Ghafouri S; Bakhtiari N; Farbood Y; Sarkaki A
    PLoS One; 2023; 18(11):e0294612. PubMed ID: 37972114
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CMT-3 targets different α-synuclein aggregates mitigating their toxic and inflammogenic effects.
    González-Lizárraga F; Ploper D; Ávila CL; Socías SB; Dos-Santos-Pereira M; Machín B; Del-Bel E; Michel PP; Pietrasanta LI; Raisman-Vozari R; Chehín R
    Sci Rep; 2020 Nov; 10(1):20258. PubMed ID: 33219264
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Unravelling the potency of triazole analogues for inhibiting α-synuclein fibrillogenesis and
    Maqbool M; Gadhavi J; Singh A; Hivare P; Gupta S; Hoda N
    Org Biomol Chem; 2021 Feb; 19(7):1589-1603. PubMed ID: 33527970
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deciphering the anti-Parkinson's activity of sulphated polysaccharides from Chlamydomonas reinhardtii on the α-Synuclein mutants A30P, A53T, E46K, E57K and E35K.
    Panigrahi GP; Rane AR; Vavilala SL; Choudhary S
    J Biochem; 2019 Dec; 166(6):463-474. PubMed ID: 31385584
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthetic Peucedanocoumarin IV Prevents α-Synuclein Neurotoxicity in an Animal Model of Parkinson's Disease.
    Kim H; Maeng HJ; Kim JH; Yoon JH; Oh Y; Paek SM; Lee Y
    Int J Mol Sci; 2022 Aug; 23(15):. PubMed ID: 35955753
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Swertiamarin from Enicostemma littorale, counteracts PD associated neurotoxicity via enhancement α-synuclein suppressive genes and SKN-1/NRF-2 activation through MAPK pathway.
    Pandey T; Shukla A; Trivedi M; Khan F; Pandey R
    Bioorg Chem; 2021 Mar; 108():104655. PubMed ID: 33548732
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.