133 related articles for article (PubMed ID: 38772503)
1. JNJ-7184, a respiratory syncytial virus inhibitor targeting the connector domain of the viral polymerase.
Bonneux B; Shareef A; Tcherniuk S; Anson B; de Bruyn S; Verheyen N; Thys K; Conceição-Neto N; Van Ginderen M; Kwanten L; Ysebaert N; Vranckx L; Peeters E; Lanckacker E; Gallup JM; Sitthicharoenchai P; Alnajjar S; Ackermann MR; Adhikary S; Bhaumik A; Patrick A; Fung A; Sutto-Ortiz P; Decroly E; Mason SW; Lançois D; Deval J; Jin Z; Eléouët JF; Fearns R; Koul A; Roymans D; Rigaux P; Herschke F
Antiviral Res; 2024 Jul; 227():105907. PubMed ID: 38772503
[TBL] [Abstract][Full Text] [Related]
2. Development of an allosteric inhibitor class blocking RNA elongation by the respiratory syncytial virus polymerase complex.
Cox RM; Toots M; Yoon JJ; Sourimant J; Ludeke B; Fearns R; Bourque E; Patti J; Lee E; Vernachio J; Plemper RK
J Biol Chem; 2018 Oct; 293(43):16761-16777. PubMed ID: 30206124
[TBL] [Abstract][Full Text] [Related]
3. Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate.
Deval J; Hong J; Wang G; Taylor J; Smith LK; Fung A; Stevens SK; Liu H; Jin Z; Dyatkina N; Prhavc M; Stoycheva AD; Serebryany V; Liu J; Smith DB; Tam Y; Zhang Q; Moore ML; Fearns R; Chanda SM; Blatt LM; Symons JA; Beigelman L
PLoS Pathog; 2015 Jun; 11(6):e1004995. PubMed ID: 26098424
[TBL] [Abstract][Full Text] [Related]
4. Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium.
Brookes DW; Coates M; Allen H; Daly L; Constant S; Huang S; Hows M; Davis A; Cass L; Ayrton J; Knowles I; Strong P; Rapeport G; Ito K
Br J Pharmacol; 2018 Jun; 175(12):2520-2534. PubMed ID: 29579332
[TBL] [Abstract][Full Text] [Related]
5. Comparative Therapeutic Potential of ALX-0171 and Palivizumab against Respiratory Syncytial Virus Clinical Isolate Infection of Well-Differentiated Primary Pediatric Bronchial Epithelial Cell Cultures.
Broadbent L; Parke HG; Ferguson LJ; Millar A; Shields MD; Detalle L; Power UF
Antimicrob Agents Chemother; 2020 Jan; 64(2):. PubMed ID: 31767728
[TBL] [Abstract][Full Text] [Related]
6. Preclinical Characterization of PC786, an Inhaled Small-Molecule Respiratory Syncytial Virus L Protein Polymerase Inhibitor.
Coates M; Brookes D; Kim YI; Allen H; Fordyce EAF; Meals EA; Colley T; Ciana CL; Parra GF; Sherbukhin V; Stockwell JA; Thomas JC; Hunt SF; Anderson-Dring L; Onions ST; Cass L; Murray PJ; Ito K; Strong P; DeVincenzo JP; Rapeport G
Antimicrob Agents Chemother; 2017 Sep; 61(9):. PubMed ID: 28652242
[TBL] [Abstract][Full Text] [Related]
7. Direct Inhibition of Cellular Fatty Acid Synthase Impairs Replication of Respiratory Syncytial Virus and Other Respiratory Viruses.
Ohol YM; Wang Z; Kemble G; Duke G
PLoS One; 2015; 10(12):e0144648. PubMed ID: 26659560
[TBL] [Abstract][Full Text] [Related]
8. Verdinexor (KPT-335), a Selective Inhibitor of Nuclear Export, Reduces Respiratory Syncytial Virus Replication
Jorquera PA; Mathew C; Pickens J; Williams C; Luczo JM; Tamir S; Ghildyal R; Tripp RA
J Virol; 2019 Feb; 93(4):. PubMed ID: 30541831
[TBL] [Abstract][Full Text] [Related]
9. GS-5806 Inhibits a Broad Range of Respiratory Syncytial Virus Clinical Isolates by Blocking the Virus-Cell Fusion Process.
Perron M; Stray K; Kinkade A; Theodore D; Lee G; Eisenberg E; Sangi M; Gilbert BE; Jordan R; Piedra PA; Toms GL; Mackman R; Cihlar T
Antimicrob Agents Chemother; 2015 Dec; 60(3):1264-73. PubMed ID: 26666922
[TBL] [Abstract][Full Text] [Related]
10. Characterization of a respiratory syncytial virus L protein inhibitor.
Tiong-Yip CL; Aschenbrenner L; Johnson KD; McLaughlin RE; Fan J; Challa S; Xiong H; Yu Q
Antimicrob Agents Chemother; 2014 Jul; 58(7):3867-73. PubMed ID: 24777090
[TBL] [Abstract][Full Text] [Related]
11. Respiratory Syncytial Virus Inhibitor AZ-27 Differentially Inhibits Different Polymerase Activities at the Promoter.
Noton SL; Nagendra K; Dunn EF; Mawhorter ME; Yu Q; Fearns R
J Virol; 2015 Aug; 89(15):7786-98. PubMed ID: 25995255
[TBL] [Abstract][Full Text] [Related]
12. A Novel Live Attenuated Respiratory Syncytial Virus Vaccine Candidate with Mutations in the L Protein SAM Binding Site and the G Protein Cleavage Site Is Protective in Cotton Rats and a Rhesus Macaque.
Jenkins T; Wang R; Harder O; Xue M; Chen P; Corry J; Walker C; Teng M; Mejias A; Ramilo O; Niewiesk S; Li J; Peeples ME
J Virol; 2021 Jan; 95(3):. PubMed ID: 33177201
[TBL] [Abstract][Full Text] [Related]
13. Respiratory syncytial virus-A dynamics and the effects of lumicitabine, a nucleoside viral replication inhibitor, in experimentally infected humans.
Patel K; Kirkpatrick CM; Nieforth KA; Chanda S; Zhang Q; McClure M; Fry J; Symons JA; Blatt LM; Beigelman L; DeVincenzo JP; Huntjens DR; Smith PF
J Antimicrob Chemother; 2019 Feb; 74(2):442-452. PubMed ID: 30376079
[TBL] [Abstract][Full Text] [Related]
14. Respiratory syncytial virus entry inhibitors targeting the F protein.
Sun Z; Pan Y; Jiang S; Lu L
Viruses; 2013 Jan; 5(1):211-25. PubMed ID: 23325327
[TBL] [Abstract][Full Text] [Related]
15. Antiviral Activity of Oral JNJ-53718678 in Healthy Adult Volunteers Challenged With Respiratory Syncytial Virus: A Placebo-Controlled Study.
Stevens M; Rusch S; DeVincenzo J; Kim YI; Harrison L; Meals EA; Boyers A; Fok-Seang J; Huntjens D; Lounis N; Mari N K; Remmerie B; Roymans D; Koul A; Verloes R
J Infect Dis; 2018 Jul; 218(5):748-756. PubMed ID: 29684148
[TBL] [Abstract][Full Text] [Related]
16. New antiviral approaches for respiratory syncytial virus and other mononegaviruses: Inhibiting the RNA polymerase.
Fearns R; Deval J
Antiviral Res; 2016 Oct; 134():63-76. PubMed ID: 27575793
[TBL] [Abstract][Full Text] [Related]
17. Design and validation of small interfering RNA on respiratory syncytial virus M2-2 gene: A potential approach in RNA interference on viral replication.
Chin VK; Atika Aziz NA; Hudu SA; Harmal NS; Syahrilnizam A; Jalilian FA; Zamberi S
J Virol Methods; 2016 Oct; 236():117-125. PubMed ID: 27432115
[TBL] [Abstract][Full Text] [Related]
18. Delivery of ALX-0171 by inhalation greatly reduces respiratory syncytial virus disease in newborn lambs.
Larios Mora A; Detalle L; Gallup JM; Van Geelen A; Stohr T; Duprez L; Ackermann MR
MAbs; 2018 Jul; 10(5):778-795. PubMed ID: 29733750
[TBL] [Abstract][Full Text] [Related]
19. Identification of Non-Nucleoside Inhibitors of the Respiratory Syncytial Virus Polymerase Complex.
Jiménez-Somarribas A; Mao S; Yoon JJ; Weisshaar M; Cox RM; Marengo JR; Mitchell DG; Morehouse ZP; Yan D; Solis I; Liotta DC; Natchus MG; Plemper RK
J Med Chem; 2017 Mar; 60(6):2305-2325. PubMed ID: 28245119
[TBL] [Abstract][Full Text] [Related]
20. Cyclopiazonic acid, an inhibitor of calcium-dependent ATPases with antiviral activity against human respiratory syncytial virus.
Cui R; Wang Y; Wang L; Li G; Lan K; Altmeyer R; Zou G
Antiviral Res; 2016 Aug; 132():38-45. PubMed ID: 27210812
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
