BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 38776963)

  • 1. Bitter taste TAS2R14 activation by intracellular tastants and cholesterol.
    Hu X; Ao W; Gao M; Wu L; Pei Y; Liu S; Wu Y; Zhao F; Sun Q; Liu J; Jiang L; Wang X; Li Y; Tan Q; Cheng J; Yang F; Yang C; Sun J; Hua T; Liu ZJ
    Nature; 2024 May; ():. PubMed ID: 38776963
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bitter taste receptor activation by cholesterol and an intracellular tastant.
    Kim Y; Gumpper RH; Liu Y; Kocak DD; Xiong Y; Cao C; Deng Z; Krumm BE; Jain MK; Zhang S; Jin J; Roth BL
    Nature; 2024 Apr; 628(8008):664-671. PubMed ID: 38600377
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reengineering the ligand sensitivity of the broadly tuned human bitter taste receptor TAS2R14.
    Nowak S; Di Pizio A; Levit A; Niv MY; Meyerhof W; Behrens M
    Biochim Biophys Acta Gen Subj; 2018 Oct; 1862(10):2162-2173. PubMed ID: 30009876
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rational design of agonists for bitter taste receptor TAS2R14: from modeling to bench and back.
    Di Pizio A; Waterloo LAW; Brox R; Löber S; Weikert D; Behrens M; Gmeiner P; Niv MY
    Cell Mol Life Sci; 2020 Feb; 77(3):531-542. PubMed ID: 31236627
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Bitter Taste Receptor TAS2R14 as a Drug Target.
    Waterloo LAW; Löber S; Gmeiner P
    Chimia (Aarau); 2022 May; 76(5):418-424. PubMed ID: 38069713
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of 2-Aminopyrimidines as Potent Agonists for the Bitter Taste Receptor TAS2R14.
    Waterloo L; Hübner H; Fierro F; Pfeiffer T; Brox R; Löber S; Weikert D; Niv MY; Gmeiner P
    J Med Chem; 2023 Mar; 66(5):3499-3521. PubMed ID: 36847646
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The bitter pill: clinical drugs that activate the human bitter taste receptor TAS2R14.
    Levit A; Nowak S; Peters M; Wiener A; Meyerhof W; Behrens M; Niv MY
    FASEB J; 2014 Mar; 28(3):1181-97. PubMed ID: 24285091
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibiting a promiscuous GPCR: iterative discovery of bitter taste receptor ligands.
    Fierro F; Peri L; Hübner H; Tabor-Schkade A; Waterloo L; Löber S; Pfeiffer T; Weikert D; Dingjan T; Margulis E; Gmeiner P; Niv MY
    Cell Mol Life Sci; 2023 Apr; 80(4):114. PubMed ID: 37012410
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Predicted structure and cell signaling of TAS2R14 reveal receptor hyper-flexibility for detecting diverse bitter tastes.
    Tokmakova A; Kim D; Guthrie B; Kim SK; Goddard WA; Liggett SB
    iScience; 2023 Apr; 26(4):106422. PubMed ID: 37096045
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functionally expressed bitter taste receptor TAS2R14 in human epidermal keratinocytes serves as a chemosensory receptor.
    Ho HK; Bigliardi PL; Stelmashenko O; Ramasamy S; Postlethwaite M; Bigliardi-Qi M
    Exp Dermatol; 2021 Feb; 30(2):216-225. PubMed ID: 33253444
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cholecystokinin, gastrin, cholecystokinin/gastrin receptors, and bitter taste receptor TAS2R14: trophoblast expression and signaling.
    Taher S; Borja Y; Cabanela L; Costers VJ; Carson-Marino M; Bailes JC; Dhar B; Beckworth MT; Rabaglino MB; Post Uiterweer ED; Conrad KP
    Am J Physiol Regul Integr Comp Physiol; 2019 May; 316(5):R628-R639. PubMed ID: 30892908
    [TBL] [Abstract][Full Text] [Related]  

  • 12. β2-Adrenergic Receptors Chaperone Trapped Bitter Taste Receptor 14 to the Cell Surface as a Heterodimer and Exert Unidirectional Desensitization of Taste Receptor Function.
    Kim D; Pauer SH; Yong HM; An SS; Liggett SB
    J Biol Chem; 2016 Aug; 291(34):17616-28. PubMed ID: 27342779
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Probing the Binding Pocket of the Broadly Tuned Human Bitter Taste Receptor TAS2R14 by Chemical Modification of Cognate Agonists.
    Karaman R; Nowak S; Di Pizio A; Kitaneh H; Abu-Jaish A; Meyerhof W; Niv MY; Behrens M
    Chem Biol Drug Des; 2016 Jul; 88(1):66-75. PubMed ID: 26825540
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural basis for strychnine activation of human bitter taste receptor TAS2R46.
    Xu W; Wu L; Liu S; Liu X; Cao X; Zhou C; Zhang J; Fu Y; Guo Y; Wu Y; Tan Q; Wang L; Liu J; Jiang L; Fan Z; Pei Y; Yu J; Cheng J; Zhao S; Hao X; Liu ZJ; Hua T
    Science; 2022 Sep; 377(6612):1298-1304. PubMed ID: 36108005
    [TBL] [Abstract][Full Text] [Related]  

  • 15. G Protein-Coupled Receptors in Taste Physiology and Pharmacology.
    Ahmad R; Dalziel JE
    Front Pharmacol; 2020; 11():587664. PubMed ID: 33390961
    [TBL] [Abstract][Full Text] [Related]  

  • 16.
    Dunkel A; Hofmann T; Di Pizio A
    J Agric Food Chem; 2020 Sep; 68(38):10414-10423. PubMed ID: 32027492
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case.
    Di Pizio A; Kruetzfeldt LM; Cheled-Shoval S; Meyerhof W; Behrens M; Niv MY
    Sci Rep; 2017 Aug; 7(1):8223. PubMed ID: 28811548
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Blocking taste receptor activation of gustducin inhibits gustatory responses to bitter compounds.
    Ming D; Ninomiya Y; Margolskee RF
    Proc Natl Acad Sci U S A; 1999 Aug; 96(17):9903-8. PubMed ID: 10449792
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BitterDB database analysis plus cell stiffness screening identify flufenamic acid as the most potent TAS2R14-based relaxant of airway smooth muscle cells for therapeutic bronchodilation.
    Ni K; Che B; Gu R; Wang C; Xu H; Li H; Cen S; Luo M; Deng L
    Theranostics; 2024; 14(4):1744-1763. PubMed ID: 38389834
    [No Abstract]   [Full Text] [Related]  

  • 20. The steroid glycoside H.g.-12 from Hoodia gordonii activates the human bitter receptor TAS2R14 and induces CCK release from HuTu-80 cells.
    Le Nevé B; Foltz M; Daniel H; Gouka R
    Am J Physiol Gastrointest Liver Physiol; 2010 Dec; 299(6):G1368-75. PubMed ID: 20930049
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.