These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 387780)

  • 1. Primary structure and properties of an inactive mutant aspartate transcarbamoylase.
    Wall KA; Schachman HK
    J Biol Chem; 1979 Dec; 254(23):11917-26. PubMed ID: 387780
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Peptide-protein interaction markedly alters the functional properties of the catalytic subunit of aspartate transcarbamoylase.
    Zhou BB; Schachman HK
    Protein Sci; 1993 Jan; 2(1):103-12. PubMed ID: 8443583
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Long range effects of amino acid substitutions in the catalytic chain of aspartate transcarbamoylase. Localized replacements in the carboxyl-terminal alpha-helix cause marked alterations in allosteric properties and intersubunit interactions.
    Peterson CB; Schachman HK
    J Biol Chem; 1992 Feb; 267(4):2443-50. PubMed ID: 1733944
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Three of the six possible intersubunit stabilizing interactions involving Glu-239 are sufficient for restoration of the homotropic and heterotropic properties of Escherichia coli aspartate transcarbamoylase.
    Sakash JB; Chan RS; Tsuruta H; Kantrowitz ER
    J Biol Chem; 2000 Jan; 275(2):752-8. PubMed ID: 10625604
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pyridoxal 5'-phosphate, a fluorescent probe in the active site of aspartate transcarbamylase.
    Kempe TD; Stark GR
    J Biol Chem; 1975 Sep; 250(17):6861-9. PubMed ID: 239951
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Function of threonine-55 in the carbamoyl phosphate binding site of Escherichia coli aspartate transcarbamoylase.
    Xu W; Kantrowitz ER
    Biochemistry; 1989 Dec; 28(26):9937-43. PubMed ID: 2515892
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The regulatory subunit of Escherichia coli aspartate carbamoyltransferase may influence homotropic cooperativity and heterotropic interactions by a direct interaction with the loop containing residues 230-245 of the catalytic chain.
    Newton CJ; Kantrowitz ER
    Proc Natl Acad Sci U S A; 1990 Mar; 87(6):2309-13. PubMed ID: 2179954
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Arginine 54 in the active site of Escherichia coli aspartate transcarbamoylase is critical for catalysis: a site-specific mutagenesis, NMR, and X-ray crystallographic study.
    Stebbins JW; Robertson DE; Roberts MF; Stevens RC; Lipscomb WN; Kantrowitz ER
    Protein Sci; 1992 Nov; 1(11):1435-46. PubMed ID: 1303763
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Site-specific substitutions of the Tyr-165 residue in the catalytic chain of aspartate transcarbamoylase promotes a T-state preference in the holoenzyme.
    Wales ME; Hoover TA; Wild JR
    J Biol Chem; 1988 May; 263(13):6109-14. PubMed ID: 3283120
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regeneration of active enzyme by formation of hybrids from inactive derivatives: implications for active sites shared between polypeptide chains of aspartate transcarbamoylase.
    Robey EA; Schachman HK
    Proc Natl Acad Sci U S A; 1985 Jan; 82(2):361-5. PubMed ID: 3881763
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aspartate transcarbamoylase containing circularly permuted catalytic polypeptide chains.
    Yang YR; Schachman HK
    Proc Natl Acad Sci U S A; 1993 Dec; 90(24):11980-4. PubMed ID: 8265657
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A 70-amino acid zinc-binding polypeptide from the regulatory chain of aspartate transcarbamoylase forms a stable complex with the catalytic subunit leading to markedly altered enzyme activity.
    Markby DW; Zhou BB; Schachman HK
    Proc Natl Acad Sci U S A; 1991 Dec; 88(23):10568-72. PubMed ID: 1961722
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of Asp222 in the catalytic mechanism of Escherichia coli aspartate aminotransferase: the amino acid residue which enhances the function of the enzyme-bound coenzyme pyridoxal 5'-phosphate.
    Yano T; Kuramitsu S; Tanase S; Morino Y; Kagamiyama H
    Biochemistry; 1992 Jun; 31(25):5878-87. PubMed ID: 1610831
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Negative complementation in aspartate transcarbamylase. Analysis of hybrid enzyme molecules containing different arrangements of polypeptide chains from wild-type and inactive mutant catalytic subunits.
    Eisenstein E; Han MS; Woo TS; Ritchey JM; Gibbons I; Yang YR; Schachman HK
    J Biol Chem; 1992 Nov; 267(31):22148-55. PubMed ID: 1429567
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vivo formation of active aspartate transcarbamoylase from complementing fragments of the catalytic polypeptide chains.
    Yang YR; Schachman HK
    Protein Sci; 1993 Jun; 2(6):1013-23. PubMed ID: 8318886
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A loop involving catalytic chain residues 230-245 is essential for the stabilization of both allosteric forms of Escherichia coli aspartate transcarbamylase.
    Middleton SA; Stebbins JW; Kantrowitz ER
    Biochemistry; 1989 Feb; 28(4):1617-26. PubMed ID: 2655696
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Changes in stability and allosteric properties of aspartate transcarbamoylase resulting from amino acid substitutions in the zinc-binding domain of the regulatory chains.
    Eisenstein E; Markby DW; Schachman HK
    Proc Natl Acad Sci U S A; 1989 May; 86(9):3094-8. PubMed ID: 2566165
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An aspartate transcarbamylase lacking catalytic subunit interactions. Study of conformational changes by ultraviolet absorbance and circular dichroism spectroscopy.
    Kerbiriou D; Hervé G
    J Biol Chem; 1977 May; 252(9):2881-90. PubMed ID: 323258
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Function of serine-52 and serine-80 in the catalytic mechanism of Escherichia coli aspartate transcarbamoylase.
    Xu W; Kantrowitz ER
    Biochemistry; 1991 Mar; 30(9):2535-42. PubMed ID: 1900434
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of amino acid substitutions on the catalytic and regulatory properties of aspartate transcarbamoylase.
    Robey EA; Wente SR; Markby DW; Flint A; Yang YR; Schachman HK
    Proc Natl Acad Sci U S A; 1986 Aug; 83(16):5934-8. PubMed ID: 3526345
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.