BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 38780621)

  • 1. Large-scale mutational analysis identifies UNC93B1 variants that drive TLR-mediated autoimmunity in mice and humans.
    Rael VE; Yano JA; Huizar JP; Slayden LC; Weiss MA; Turcotte EA; Terry JM; Zuo W; Thiffault I; Pastinen T; Farrow EG; Jenkins JL; Becker ML; Wong SC; Stevens AM; Otten C; Allenspach EJ; Bonner DE; Bernstein JA; Wheeler MT; Saxton RA; ; Liu B; Majer O; Barton GM
    J Exp Med; 2024 Aug; 221(8):. PubMed ID: 38780621
    [TBL] [Abstract][Full Text] [Related]  

  • 2. UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major.
    Schamber-Reis BL; Petritus PM; Caetano BC; Martinez ER; Okuda K; Golenbock D; Scott P; Gazzinelli RT
    J Biol Chem; 2013 Mar; 288(10):7127-36. PubMed ID: 23325805
    [TBL] [Abstract][Full Text] [Related]  

  • 3. UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity.
    Majer O; Liu B; Kreuk LSM; Krogan N; Barton GM
    Nature; 2019 Nov; 575(7782):366-370. PubMed ID: 31546246
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing.
    Fukui R; Saitoh S; Matsumoto F; Kozuka-Hata H; Oyama M; Tabeta K; Beutler B; Miyake K
    J Exp Med; 2009 Jun; 206(6):1339-50. PubMed ID: 19451267
    [TBL] [Abstract][Full Text] [Related]  

  • 5. UNC93B1 variants underlie TLR7-dependent autoimmunity.
    Wolf C; Lim EL; Mokhtari M; Kind B; Odainic A; Lara-Villacanas E; Koss S; Mages S; Menzel K; Engel K; Dückers G; Bernbeck B; Schneider DT; Siepermann K; Niehues T; Goetzke CC; Durek P; Minden K; Dörner T; Stittrich A; Szelinski F; Guerra GM; Massoud M; Bieringer M; de Oliveira Mann CC; Beltrán E; Kallinich T; Mashreghi MF; Schmidt SV; Latz E; Klughammer J; Majer O; Lee-Kirsch MA
    Sci Immunol; 2024 Feb; 9(92):eadi9769. PubMed ID: 38207055
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
    Pelka K; Bertheloot D; Reimer E; Phulphagar K; Schmidt SV; Christ A; Stahl R; Watson N; Miyake K; Hacohen N; Haas A; Brinkmann MM; Marshak-Rothstein A; Meissner F; Latz E
    Immunity; 2018 May; 48(5):911-922.e7. PubMed ID: 29768176
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking.
    Fukui R; Saitoh S; Kanno A; Onji M; Shibata T; Ito A; Onji M; Matsumoto M; Akira S; Yoshida N; Miyake K
    Immunity; 2011 Jul; 35(1):69-81. PubMed ID: 21683627
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Polymorphisms and expression of toll-like receptors in autoimmune thyroid diseases.
    Inoue N; Katsumata Y; Watanabe M; Ishido N; Manabe Y; Watanabe A; Masutani R; Hidaka Y; Iwatani Y
    Autoimmunity; 2017 May; 50(3):182-191. PubMed ID: 28013570
    [TBL] [Abstract][Full Text] [Related]  

  • 9. UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes.
    Kim YM; Brinkmann MM; Paquet ME; Ploegh HL
    Nature; 2008 Mar; 452(7184):234-8. PubMed ID: 18305481
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Release from UNC93B1 reinforces the compartmentalized activation of select TLRs.
    Majer O; Liu B; Woo BJ; Kreuk LSM; Van Dis E; Barton GM
    Nature; 2019 Nov; 575(7782):371-374. PubMed ID: 31546247
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Variants Affecting the C-Terminal Tail of UNC93B1 Are Not a Common Risk Factor for Systemic Lupus Erythematosus.
    Kiener S; Ribi C; Keller I; Chizzolini C; Trendelenburg M; Huynh-Do U; von Kempis J; On Behalf Of Swiss Sle Cohort Study Sscs ; Leeb T
    Genes (Basel); 2021 Aug; 12(8):. PubMed ID: 34440442
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus.
    Al-Azab M; Idiiatullina E; Liu Z; Lin M; Hrovat-Schaale K; Xian H; Zhu J; Yang M; Lu B; Zhao Z; Liu Y; Chang J; Li X; Guo C; Liu Y; Wu Q; Chen J; Lan C; Zeng P; Cui J; Gao X; Zhou W; Zhang Y; Zhang Y; Masters SL
    Nat Immunol; 2024 Jun; 25(6):969-980. PubMed ID: 38831104
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cryo-EM structures of Toll-like receptors in complex with UNC93B1.
    Ishida H; Asami J; Zhang Z; Nishizawa T; Shigematsu H; Ohto U; Shimizu T
    Nat Struct Mol Biol; 2021 Feb; 28(2):173-180. PubMed ID: 33432245
    [TBL] [Abstract][Full Text] [Related]  

  • 14. UNC93B1 mediates differential trafficking of endosomal TLRs.
    Lee BL; Moon JE; Shu JH; Yuan L; Newman ZR; Schekman R; Barton GM
    Elife; 2013 Feb; 2():e00291. PubMed ID: 23426999
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection.
    Lafferty EI; Flaczyk A; Angers I; Homer R; d'Hennezel E; Malo D; Piccirillo CA; Vidal SM; Qureshi ST
    Genes Immun; 2014; 15(5):320-32. PubMed ID: 24848930
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gain-of-function human UNC93B1 variants cause systemic lupus erythematosus and chilblain lupus.
    David C; Arango-Franco CA; Badonyi M; Fouchet J; Rice GI; Didry-Barca B; Maisonneuve L; Seabra L; Kechiche R; Masson C; Cobat A; Abel L; Talouarn E; Béziat V; Deswarte C; Livingstone K; Paul C; Malik G; Ross A; Adam J; Walsh J; Kumar S; Bonnet D; Bodemer C; Bader-Meunier B; Marsh JA; Casanova JL; Crow YJ; Manoury B; Frémond ML; Bohlen J; Lepelley A
    J Exp Med; 2024 Aug; 221(8):. PubMed ID: 38869500
    [TBL] [Abstract][Full Text] [Related]  

  • 17. UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA
    Klammer MG; Dzaye O; Wallach T; Krüger C; Gaessler D; Buonfiglioli A; Derkow K; Kettenmann H; Brinkmann MM; Lehnardt S
    Front Immunol; 2021; 12():715774. PubMed ID: 34589086
    [TBL] [Abstract][Full Text] [Related]  

  • 18. UNC93B1 curbs cytosolic DNA signaling by promoting STING degradation.
    He Z; Ye S; Xing Y; Jiu Y; Zhong J
    Eur J Immunol; 2021 Jul; 51(7):1672-1685. PubMed ID: 33837956
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN.
    Pollard KM; Escalante GM; Huang H; Haraldsson KM; Hultman P; Christy JM; Pawar RD; Mayeux JM; Gonzalez-Quintial R; Baccala R; Beutler B; Theofilopoulos AN; Kono DH
    J Immunol; 2017 Dec; 199(11):3739-3747. PubMed ID: 29055005
    [TBL] [Abstract][Full Text] [Related]  

  • 20. N-glycosylation of UNC93B1 at a Specific Asparagine Residue Is Required for TLR9 Signaling.
    Song HS; Park S; Huh JW; Lee YR; Jung DJ; Yang C; Kim SH; Kim HM; Kim YM
    Front Immunol; 2022; 13():875083. PubMed ID: 35874766
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.