166 related articles for article (PubMed ID: 38782989)
1. Impact of secretin receptor homo-dimerization on natural ligand binding.
Harikumar KG; Piper SJ; Christopoulos A; Wootten D; Sexton PM; Miller LJ
Nat Commun; 2024 May; 15(1):4390. PubMed ID: 38782989
[TBL] [Abstract][Full Text] [Related]
2. Mapping spatial approximations between the amino terminus of secretin and each of the extracellular loops of its receptor using cysteine trapping.
Dong M; Xu X; Ball AM; Makhoul JA; Lam PC; Pinon DI; Orry A; Sexton PM; Abagyan R; Miller LJ
FASEB J; 2012 Dec; 26(12):5092-105. PubMed ID: 22964305
[TBL] [Abstract][Full Text] [Related]
3. Use of Cysteine Trapping to Map Spatial Approximations between Residues Contributing to the Helix N-capping Motif of Secretin and Distinct Residues within Each of the Extracellular Loops of Its Receptor.
Dong M; Lam PC; Orry A; Sexton PM; Christopoulos A; Abagyan R; Miller LJ
J Biol Chem; 2016 Mar; 291(10):5172-84. PubMed ID: 26740626
[TBL] [Abstract][Full Text] [Related]
4. Spatial approximation between secretin residue five and the third extracellular loop of its receptor provides new insight into the molecular basis of natural agonist binding.
Dong M; Lam PC; Pinon DI; Sexton PM; Abagyan R; Miller LJ
Mol Pharmacol; 2008 Aug; 74(2):413-22. PubMed ID: 18467541
[TBL] [Abstract][Full Text] [Related]
5. Lactam constraints provide insights into the receptor-bound conformation of secretin and stabilize a receptor antagonist.
Dong M; Te JA; Xu X; Wang J; Pinon DI; Storjohann L; Bordner AJ; Miller LJ
Biochemistry; 2011 Sep; 50(38):8181-92. PubMed ID: 21851058
[TBL] [Abstract][Full Text] [Related]
6. Fluorescence resonance energy transfer analysis of secretin docking to its receptor: mapping distances between residues distributed throughout the ligand pharmacophore and distinct receptor residues.
Harikumar KG; Lam PC; Dong M; Sexton PM; Abagyan R; Miller LJ
J Biol Chem; 2007 Nov; 282(45):32834-43. PubMed ID: 17827151
[TBL] [Abstract][Full Text] [Related]
7. Molecular basis of secretin docking to its intact receptor using multiple photolabile probes distributed throughout the pharmacophore.
Dong M; Lam PC; Pinon DI; Hosohata K; Orry A; Sexton PM; Abagyan R; Miller LJ
J Biol Chem; 2011 Jul; 286(27):23888-99. PubMed ID: 21566140
[TBL] [Abstract][Full Text] [Related]
8. Structure and dynamics of the active Gs-coupled human secretin receptor.
Dong M; Deganutti G; Piper SJ; Liang YL; Khoshouei M; Belousoff MJ; Harikumar KG; Reynolds CA; Glukhova A; Furness SGB; Christopoulos A; Danev R; Wootten D; Sexton PM; Miller LJ
Nat Commun; 2020 Aug; 11(1):4137. PubMed ID: 32811827
[TBL] [Abstract][Full Text] [Related]
9. Ligand binding and activation of the secretin receptor, a prototypic family B G protein-coupled receptor.
Miller LJ; Dong M; Harikumar KG
Br J Pharmacol; 2012 May; 166(1):18-26. PubMed ID: 21542831
[TBL] [Abstract][Full Text] [Related]
10. Functional importance of a structurally distinct homodimeric complex of the family B G protein-coupled secretin receptor.
Gao F; Harikumar KG; Dong M; Lam PC; Sexton PM; Christopoulos A; Bordner A; Abagyan R; Miller LJ
Mol Pharmacol; 2009 Aug; 76(2):264-74. PubMed ID: 19429716
[TBL] [Abstract][Full Text] [Related]
11. Structure and Function of Cross-class Complexes of G Protein-coupled Secretin and Angiotensin 1a Receptors.
Harikumar KG; Augustine ML; Lee LT; Chow BK; Miller LJ
J Biol Chem; 2016 Aug; 291(33):17332-44. PubMed ID: 27330080
[TBL] [Abstract][Full Text] [Related]
12. Structural basis of natural ligand binding and activation of the Class II G-protein-coupled secretin receptor.
Miller LJ; Dong M; Harikumar KG; Gao F
Biochem Soc Trans; 2007 Aug; 35(Pt 4):709-12. PubMed ID: 17635130
[TBL] [Abstract][Full Text] [Related]
13. Spatial intensity distribution analysis quantifies the extent and regulation of homodimerization of the secretin receptor.
Ward RJ; Pediani JD; Harikumar KG; Miller LJ; Milligan G
Biochem J; 2017 May; 474(11):1879-1895. PubMed ID: 28424368
[TBL] [Abstract][Full Text] [Related]
14. Coexpressed Class B G Protein-Coupled Secretin and GLP-1 Receptors Self- and Cross-Associate: Impact on Pancreatic Islets.
Harikumar KG; Lau S; Sexton PM; Wootten D; Miller LJ
Endocrinology; 2017 Jun; 158(6):1685-1700. PubMed ID: 28368447
[TBL] [Abstract][Full Text] [Related]
15. Elucidation of the active conformation of the amino terminus of receptor-bound secretin using intramolecular disulfide bond constraints.
Dong M; Pinon DI; Bordner AJ; Miller LJ
Bioorg Med Chem Lett; 2010 Oct; 20(20):6040-4. PubMed ID: 20813522
[TBL] [Abstract][Full Text] [Related]
16. Structure of the human secretin receptor coupled to an engineered heterotrimeric G protein.
Fukuhara S; Kobayashi K; Kusakizako T; Iida W; Kato M; Shihoya W; Nureki O
Biochem Biophys Res Commun; 2020 Dec; 533(4):861-866. PubMed ID: 33008599
[TBL] [Abstract][Full Text] [Related]
17. Interaction among four residues distributed through the secretin pharmacophore and a focused region of the secretin receptor amino terminus.
Dong M; Zang M; Pinon DI; Li Z; Lybrand TP; Miller LJ
Mol Endocrinol; 2002 Nov; 16(11):2490-501. PubMed ID: 12403838
[TBL] [Abstract][Full Text] [Related]
18. Importance of each residue within secretin for receptor binding and biological activity.
Dong M; Le A; Te JA; Pinon DI; Bordner AJ; Miller LJ
Biochemistry; 2011 Apr; 50(14):2983-93. PubMed ID: 21388146
[TBL] [Abstract][Full Text] [Related]
19. Molecular basis of association of receptor activity-modifying protein 3 with the family B G protein-coupled secretin receptor.
Harikumar KG; Simms J; Christopoulos G; Sexton PM; Miller LJ
Biochemistry; 2009 Dec; 48(49):11773-85. PubMed ID: 19886671
[TBL] [Abstract][Full Text] [Related]
20. Spatial approximation between two residues in the mid-region of secretin and the amino terminus of its receptor. Incorporation of seven sets of such constraints into a three-dimensional model of the agonist-bound secretin receptor.
Dong M; Li Z; Zang M; Pinon DI; Lybrand TP; Miller LJ
J Biol Chem; 2003 Nov; 278(48):48300-12. PubMed ID: 14500709
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
