BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 38791291)

  • 1. The Functional Roles of the Src Homology 2 Domain-Containing Inositol 5-Phosphatases SHIP1 and SHIP2 in the Pathogenesis of Human Diseases.
    Müller SM; Jücker M
    Int J Mol Sci; 2024 May; 25(10):. PubMed ID: 38791291
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Therapeutic potential of SH2 domain-containing inositol-5'-phosphatase 1 (SHIP1) and SHIP2 inhibition in cancer.
    Fuhler GM; Brooks R; Toms B; Iyer S; Gengo EA; Park MY; Gumbleton M; Viernes DR; Chisholm JD; Kerr WG
    Mol Med; 2012 Feb; 18(1):65-75. PubMed ID: 22033675
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous leukemia progenitor cells.
    Wisniewski D; Strife A; Swendeman S; Erdjument-Bromage H; Geromanos S; Kavanaugh WM; Tempst P; Clarkson B
    Blood; 1999 Apr; 93(8):2707-20. PubMed ID: 10194451
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2.
    Bradshaw WJ; Kennedy EC; Moreira T; Smith LA; Chalk R; Katis VL; Benesch JLP; Brennan PE; Murphy EJ; Gileadi O
    Structure; 2024 Apr; 32(4):453-466.e6. PubMed ID: 38309262
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SH2-containing inositol 5-phosphatases 1 and 2 in blood platelets: their interactions and roles in the control of phosphatidylinositol 3,4,5-trisphosphate levels.
    Giuriato S; Pesesse X; Bodin S; Sasaki T; Viala C; Marion E; Penninger J; Schurmans S; Erneux C; Payrastre B
    Biochem J; 2003 Nov; 376(Pt 1):199-207. PubMed ID: 12885297
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The SH2 domains of inositol polyphosphate 5-phosphatases SHIP1 and SHIP2 have similar ligand specificity but different binding kinetics.
    Zhang Y; Wavreille AS; Kunys AR; Pei D
    Biochemistry; 2009 Nov; 48(46):11075-83. PubMed ID: 19839650
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small molecule targeting of SHIP1 and SHIP2.
    Kerr WG; Pedicone C; Dormann S; Pacherille A; Chisholm JD
    Biochem Soc Trans; 2020 Feb; 48(1):291-300. PubMed ID: 32049315
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PTEN and Other PtdIns(3,4,5)P
    Csolle MP; Ooms LM; Papa A; Mitchell CA
    Int J Mol Sci; 2020 Dec; 21(23):. PubMed ID: 33276499
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanisms controlling membrane recruitment and activation of the autoinhibited SHIP1 inositol 5-phosphatase.
    Waddell GL; Drew EE; Rupp HP; Hansen SD
    J Biol Chem; 2023 Aug; 299(8):105022. PubMed ID: 37423304
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Overexpression of SH2-Containing Inositol Phosphatase Contributes to Chronic Lymphocytic Leukemia Survival.
    Pal Singh S; de Bruijn MJW; Velaso Gago da Graça C; Corneth OBJ; Rip J; Stadhouders R; Meijers RWJ; Schurmans S; Kerr WG; Ter Burg J; Eldering E; Langerak AW; Pillai SY; Hendriks RW
    J Immunol; 2020 Jan; 204(2):360-374. PubMed ID: 31836657
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The two SH2-domain-containing inositol 5-phosphatases SHIP1 and SHIP2 are coexpressed in human T lymphocytes.
    Bruyns C; Pesesse X; Moreau C; Blero D; Erneux C
    Biol Chem; 1999; 380(7-8):969-74. PubMed ID: 10494849
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Leukemia-associated mutations in SHIP1 inhibit its enzymatic activity, interaction with the GM-CSF receptor and Grb2, and its ability to inactivate PI3K/AKT signaling.
    Brauer H; Strauss J; Wegner W; Müller-Tidow C; Horstmann M; Jücker M
    Cell Signal; 2012 Nov; 24(11):2095-101. PubMed ID: 22820502
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The termination of PI3K signalling by SHIP1 and SHIP2 inositol 5-phosphatases.
    Backers K; Blero D; Paternotte N; Zhang J; Erneux C
    Adv Enzyme Regul; 2003; 43():15-28. PubMed ID: 12791379
    [No Abstract]   [Full Text] [Related]  

  • 14. Preclinical Evaluation of a Novel SHIP1 Phosphatase Activator for Inhibition of PI3K Signaling in Malignant B Cells.
    Lemm EA; Valle-Argos B; Smith LD; Richter J; Gebreselassie Y; Carter MJ; Karolova J; Svaton M; Helman K; Weston-Bell NJ; Karydis L; Williamson CT; Lenz G; Pettigrew J; Harwig C; Stevenson FK; Cragg M; Forconi F; Steele AJ; Cross J; Mackenzie L; Klener P; Packham G
    Clin Cancer Res; 2020 Apr; 26(7):1700-1711. PubMed ID: 31831562
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase, SHIP2.
    Suwa A; Yamamoto T; Sawada A; Minoura K; Hosogai N; Tahara A; Kurama T; Shimokawa T; Aramori I
    Br J Pharmacol; 2009 Oct; 158(3):879-87. PubMed ID: 19694723
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Src Homology 2 Domain-Containing Inositol 5'-Phosphatase Ameliorates High Glucose-Induced Extracellular Matrix Deposition via the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway in Renal Tubular Epithelial Cells.
    Li F; Li L; Hao J; Liu S; Duan H
    J Cell Biochem; 2017 Aug; 118(8):2271-2284. PubMed ID: 28075049
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SHIP2 is recruited to the cell membrane upon macrophage colony-stimulating factor (M-CSF) stimulation and regulates M-CSF-induced signaling.
    Wang Y; Keogh RJ; Hunter MG; Mitchell CA; Frey RS; Javaid K; Malik AB; Schurmans S; Tridandapani S; Marsh CB
    J Immunol; 2004 Dec; 173(11):6820-30. PubMed ID: 15557176
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SHIP inhibition mediates select TREM2-induced microglial functions.
    Ramakrishnan GS; Berry WL; Pacherille A; Kerr WG; Chisholm JD; Pedicone C; Humphrey MB
    Mol Immunol; 2024 Jun; 170():35-45. PubMed ID: 38613944
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SHIP1 and its role for innate immune regulation-Novel targets for immunotherapy.
    Yeoh WJ; Krebs P
    Eur J Immunol; 2023 Dec; 53(12):e2350446. PubMed ID: 37742135
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Src homology 2 domain-containing inositol-5-phosphatase 1 (SHIP1) negatively regulates TLR4-mediated LPS response primarily through a phosphatase activity- and PI-3K-independent mechanism.
    An H; Xu H; Zhang M; Zhou J; Feng T; Qian C; Qi R; Cao X
    Blood; 2005 Jun; 105(12):4685-92. PubMed ID: 15701712
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.